Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Yu Yan"'
Publikováno v:
Molecular Therapy. Methods & Clinical Development
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 791-802 (2020)
Molecular Therapy: Methods & Clinical Development, Vol 18, Iss, Pp 791-802 (2020)
Transforming growth factor β (TGF-β)/Smad3 signaling plays a central role in chronic heart disease. Here, we report that targeting Smad3 with a Smad3 inhibitor SIS3 in an established mouse model of hypertension significantly improved cardiac dysfun
Autor:
Li‑Jie Zhang, Rong Wen, Hong Yang, Yong‑Ying Qin, Jun‑Lin Yang, Jun Wang, Deng‑Hua Pan, Yu‑Yan Pang, Qin‑Qiao Lai, Yu He, Jing‑Ni Lai, Xiao‑Jiao Li, Lin Shi, Jun Ma, Dong‑Yue Wen, Yun‑Hui Lai, Peng Lin
Publikováno v:
Molecular Medicine Reports
Thyroid cancer (TC) is a frequently occurring malignant tumor with a rising steadily incidence. microRNA (miRNA/miR)-193a-3p is an miRNA that is associated with tumors, playing a crucial role in the genesis and progression of various cancers. However
Autor:
Qin-Sheng Mao, Wan-Jiang Xue, Yang Su, Peng Li, Yi-Lin Hu, Jia-Zhou Liu, Hua Huang, Yu-yan Chen, Ying Feng
Publikováno v:
Journal of Cellular and Molecular Medicine
The mechanism by which miR‐605‐3p regulates hepatocellular carcinoma (HCC) metastasis has not been clarified. In this study, we found that miR‐605‐3p was down‐regulated in HCC and that low miR‐605‐3p expression was associated with tumou
Autor:
Yu Yan, Qiaoling Song, Xiaohan Xu, Lei Zhang, Xinxin Zhang, Yazhuo Zhang, Jie Wang, Chenyang Zhao, Liangliang Lu, Mengyuan Li, Yidan Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
JAK/STAT and NFκB signalling pathways play essential roles in regulating inflammatory responses, which are important pathogenic factors of various serious immune‐related diseases, and function individually or synergistically. To find prodrugs that
Autor:
Jing Su, Xin-Ru Zhong, Li-Chao Zhang, Sihang Yu, Xiao-Yu Yan, Yong Zhang, Liankun Sun, Yanan Liu
Publikováno v:
Journal of Cellular and Molecular Medicine
Increasing evidence suggests that p62/SQSTM1 functions as a signalling centre in cancer. However, the role of p62 in tumour development depends on the interacting factors it recruits and its precise regulatory mechanism remains unclear. In this study
Autor:
Gen Li, Pingchen Zhang, Wei-Shan Zhang, Sheng-Di Chen, Yixi He, Jin Liu, Yu-Yan Tan, Xin Shen, Shi-Shuang Cui, Guiying He
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
Background: The mechanisms of Parkinson's disease (PD) include complicated genetic factors. The roles of newly found risk genes need to be further verified among different ethnicities. In a two-stage meta-analysis, single nucleotide polymorphism (SNP
Autor:
Chen Chen, Guan-Zhi Liu, Yue-Yuan Liao, Chao Chu, Wen-Ling Zheng, Yang Wang, Jia-Wen Hu, Qiong Ma, Ke-Ke Wang, Yu Yan, Yue Yuan, Jian-Jun Mu
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
In the current study, we aimed to identify potential biomarkers for salt sensitivity of blood pressure (SSBP), which may provide a novel insight into the pathogenic mechanisms of salt-sensitive hypertension. Firstly, we conducted weighted gene coexpr
Publikováno v:
Frontiers in Genetics
Frontiers in Genetics, Vol 11 (2020)
Frontiers in Genetics, Vol 11 (2020)
Apis cerana is one of the main honeybee species in artificial farming, which is widely distributed in Asian countries. The genome of A. cerana has been sequenced by several different research groups using second generation sequencing technologies. Ho
Autor:
Yu, Li, Shu, Hong, Zhou, Nian, Xing, Lu, Lv, Meng-Xing, Li, Li, Xie, Yu-Cheng, Zhang, Zhao, Zhang, Li, Xie, Yu-Yan
Publikováno v:
Molecular Medicine Reports
Infantile hemangioma (IH) is one of the most common vascular tumors that occurs during childhood, but its pathogenesis is currently not completely understood. Even though lncRNA nuclear paraspeckle assembly transcript 1 (NEAT1) plays vital roles in t
Publikováno v:
Molecular Medicine Reports
Differential expression of microRNA (miR)-335-5p, a key tumor suppressor, has been detected in pre-eclampsia (PE) placentas. However, the role of miR-335-5p in the pathogenesis of PE and the factor modulating its aberrant expression remain unknown. T