Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Quansheng Zhou"'
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1876(1)
Increasing evidence shows that numerous cancer-testis antigens (CTAs) are uniquely overexpressed in various types of cancer and most CTAs are oncogenic. Overexpression of oncogenic CTAs promotes carcinogenesis, cancer metastasis, and drug resistance.
Autor:
Jindan Qi, Shufen Xiang, Tong Zhang, Quansheng Zhou, Mengli Zhang, Yijun Wei, Mei Meng, Jun Yao, Xiaohua Wang, Zhe Zhao
Publikováno v:
Cell Death and Disease, Vol 11, Iss 5, Pp 1-14 (2020)
Cell Death & Disease
Cell Death & Disease
Salvador homolog-1 (SAV1) is a tumor suppressor required for activation of the tumor-suppressive Hippo pathway and inhibition of tumorigenesis. SAV1 is defective in several cancer types. SAV1 deficiency in cells promotes tumorigenesis and cancer meta
Autor:
Zhe Zhao, Tong Zhang, Yingnan Qiao, Mei Meng, Jindan Qi, Xiaohua Wang, Bin Zhang, Quansheng Zhou, Shijie Tan, Mengli Zhang
Publikováno v:
Biochemical Pharmacology. 185:114423
Metastatic melanoma has a very high mortality rate despite the availability of chemotherapy, radiotherapy, and immunotherapy; therefore, more effective therapeutics are needed. The Hippo pathway plays an inhibitory role in melanoma progression, but t
Publikováno v:
Toxicology and applied pharmacology. 388
Gastric cancer ranks as the third leading cause of cancer-related death worldwide. The uncontrolled tumor growth and robust metastasis are key factors to cause the cancer patient death. Mechanistically, aberrant activation of Notch and NF-κB signali
Publikováno v:
Journal of cellular physiology. 234(7)
Metastatic melanoma accounts for 60% of death for skin cancer. Although great efforts have been made to treat the disease, effective drugs against metastatic melanoma still lack at the clinical setting. In the current study, we found that lycorine, a