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Autor:
Rong-Chi Huang, Hsin-Yi Lin
Publikováno v:
Biomedical Journal. 45:143-154
Background The central clock of the suprachiasmatic nucleus (SCN) controls the metabolism of glucose and is sensitive to glucose shortage. However, it is only beginning to be understood how metabolic signals such as glucose availability regulate the
Autor:
Thijs ten Doesschate, Anouk E. Muller, Irene A.M. Groenewegen, Kelly Hendriks, T.N. Platteel, Suzanne E. Geerlings, Andy I.M. Hoepelman, Evelien C. van der Hout, Cornelis H. van Werkhoven, Marc J. M. Bonten
Publikováno v:
Clinical Microbiology and Infection, 28(2), 248-254. Elsevier Ltd.
Clinical microbiology and infection. Elsevier Limited
Clinical microbiology and infection. Elsevier Limited
Objectives: Guidelines do not distinguish between 50 mg or 100 mg nitrofurantoin as daily prophylaxis for recurrent urinary tract infection (UTI), although 50 mg might have a better safety profile. Our objective was to compare the effectiveness and s
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 1, Pp 107-113 (2022)
Background The emergence of concurrent levofloxacin- and trimethoprim/sulfamethoxazole (TMP/SMX)-resistant Stenotrophomonas maltophilia (LTSRSM) in Taiwan is becoming a serious problem, but clinical data analysis on this has not been reported. Method
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 21:130-149
Arachidonic acids and its metabolites modulate plenty of ligand-gated, voltage-dependent ion channels, and metabolically regulated potassium channels including ATP-sensitive potassium channels (KATP). KATP channels are hetero-multimeric complexes of
Autor:
Francesca Ragusa, Alessandro Antonelli, Gilda Varricchi, Poupak Fallahi, Maria Rosaria Galdiero, Giusy Elia, Salvatore Benvenga, Silvia Martina Ferrari, Sabrina Rosaria Paparo
Publikováno v:
Seminars in Cancer Biology. 79:180-196
Thyroid cancer (TC) is the eighth most frequently diagnosed cancer worldwide with a rising incidence in the past 20 years. Surgery is the primary strategy of therapy for patients with medullary TC (MTC) and differentiated TC (DTC). In DTC patients, r
Autor:
Yi Tzu Lee, Feng Huei Lin, Ying shih Su, Yu Min Huang, Yung Chih Wang, Shu Wei Huang, Ming Tsung Sun, Wen Sen Lee, Ming-Hsien Chiang, Ya Sung Yang, Shian Chiuan Tzeng
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 55, Iss 1, Pp 51-59 (2022)
Background Tigecycline is an antibiotic that well tolerated for treating complicated infections. It has received attention as an anti-cancer agent and expected to solve two major obstacles, sides effects that accompany chemotherapy and drug resistanc
Autor:
Veronica Falcone, Georg Pfeiler, Zsuzsanna Bago-Horvath, Christian F. Singer, Anja Catic, Christine Deutschmann, Lenka Grula, Myriam Stolz, E Reiser
Publikováno v:
Clinical Breast Cancer. 22:149-160
Background Neoadjuvant chemotherapy (NAC) in combination with anti-HER2 treatment is standard of care in patients with early HER2 positive breast cancer. Preoperative radiological evaluation is mandatory for defining the extent of surgery. In this st
Publikováno v:
BMJ Case Rep
A 75-year-old man was admitted with a 3-month history of worsening diarrhoea and weight loss. He was on long-term immunosuppression following cardiac transplantation. Investigations revealed herpes simplex oesophagitis and stool samples were positive
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-6 (2018)
Objective Tegaserod is a 5-hydroxytryptamine type 4 (5-HT4) receptor agonist, formerly used in treating constipation predominant irritable bowel syndrome, which desensitizes 5-HT4 receptors in rat oesophagus and colon in vitro. Desensitization of 5-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c038d0b77514f3b8f3530f940cff3886
Autor:
Louis B. Nabors, David A. Reardon, John Simes, Lisa Roberts-Rapp, Ho-Jin Lee, Nicholas Butowski, Tobias Walbert, Andrew B. Lassman, Helen Wheeler, Priya Kumthekar, Andrew M. Scott, Peter Ansell, Tom Mikkelsen, Marta Penas-Prado, Kyriakos P. Papadopoulos, Martin J. van den Bent, Earle Bain, Zarnie Lwin, Erica Gomez, David Maag, Ryan Merrell, Hui K Gan, Hao Xiong, Kyle D. Holen
Publikováno v:
Cancer Chemotherapy & Pharmacology, 80(6), 1209-1217. Springer-Verlag
Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology
Purpose Patients with recurrent glioblastoma (rGBM) have a poor prognosis. Epidermal growth factor receptor (EGFR) gene amplification is present in ~ 50% of glioblastomas (GBMs). Depatuxizumab mafodotin (depatux-m), formerly ABT-414, is an antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff65c6833473b7cdb380bda35882ca5