Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jiri Bartek"'
Autor:
Andrea Daniela Maier, Tiit Mathiesen, Jiri Bartek, Fredrika Svahn, Jan Zedenius, Christian Mirian, Helle Broholm, Adam Stenman, Marianne Juhler
Publikováno v:
Brain Pathology
Purpose: TERT promoter mutation (TERTpMut) has a strong association to recurrence and has been suggested to act as a driver mutation for malignant transformation of WHO grade I and II meningiomas. TERTpMut has been investigated in selected high‐gra
Autor:
Zdenek Hodny, Jirina Bartkova, Mariam Gachechiladze, Dana Simkova, Martin Mistrik, Dusana Majera, Jan Bouchal, Jana Steigerova, Karel Cwiertka, Jan Gursky, Gabriela Korinkova, Zdenek Skrott, Daniela Kurfürstová, Jiri Bartek
Publikováno v:
The Prostate. 79:352-362
Background Castration-resistant prostate cancer (PCa) represents a serious health challenge. Based on mechanistically-supported rationale we explored new therapeutic options based on clinically available drugs with anticancer effects, including inhib
Autor:
Thomas Skoglund, Roger Henriksson, Isabelle Rydén, Øyvind Salvesen, Anja Smits, Asgeir Store Jakola, Sasha Gulati, Göran Hesselager, Erik Thurin, Jiri Bartek
Publikováno v:
Cancer Medicine, Vol 10, Iss 9, Pp 2967-2977 (2021)
Cancer Medicine
Cancer Medicine
Background Meningioma is the most common primary intracranial tumor and surgery is the main treatment modality. As death from lack of tumor control is rare, other outcome measures like anxiety, depression and post‐operative epilepsy are becoming in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f09275e425043beb65ffe5793726f04
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-182158
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-182158
Autor:
Zlatko Dembic, Siniša Volarević, Slađana Bursać, Ines Orsolic, Irena Drmic Hofman, Jiri Bartek, Deana Jurada, Ivana Mihalek
Publikováno v:
Oncogene
Volume 39
Issue 17
Volume 39
Issue 17
Perturbations in ribosome biogenesis have been associated with cancer. Such aberrations activate p53 through the RPL5/RPL11/5S rRNA complex-mediated inhibition of HDM2. Studies using animal models have suggested that this signaling pathway might cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57d47f36aa0267560b68dda91b7cf2b5
https://repository.medri.uniri.hr/islandora/object/medri:3505/datastream/FILE0
https://repository.medri.uniri.hr/islandora/object/medri:3505/datastream/FILE0
Autor:
Jesper V. Olsen, Diego Iglesias-Gato, Kim Hjorth-Jensen, Apolinar Maya-Mendoza, Jiri Bartek, Nanna Dalgaard, Amilcar Flores-Morales, Jón Otti Sigurðsson
Publikováno v:
Nucleic Acids Research
Hjorth-Jensen, K, Maya-Mendoza, A, Dalgaard, N, Sigurðsson, J O, Bartek, J, Iglesias-Gato, D, Olsen, J V & Flores-Morales, A 2018, ' SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability ', Nucleic Acids Research, vol. 46, no. 18, pp. 9484-9495 . https://doi.org/10.1093/nar/gky719
Hjorth-Jensen, K, Maya-Mendoza, A, Dalgaard, N, Sigurðsson, J O, Bartek, J, Iglesias-Gato, D, Olsen, J V & Flores-Morales, A 2018, ' SPOP promotes transcriptional expression of DNA repair and replication factors to prevent replication stress and genomic instability ', Nucleic Acids Research, vol. 46, no. 18, pp. 9484-9495 . https://doi.org/10.1093/nar/gky719
Mutations in SPOP, the gene most frequently point-mutated in primary prostate cancer, are associated with a high degree of genomic instability and deficiency in homologous recombination repair of DNA but the underlying mechanisms behind this defect a
Autor:
Filip Novotny, Rastislav Dzijak, Ivan Stepanek, Filip Havel, Andrea Babelova, Michal Sramek, Monika Zarska, Kamil Musilek, Jiri Bartek, Ondrej Novak, J. Proska, Blanka Mrazkova, Monika Ursinyova, Zdenek Hodny, Oldrich Benada, Milan Reiniš, Kamil Kuca
Publikováno v:
Biomaterials
The exceptionally high cellular uptake of gold nanorods (GNRs) bearing cationic surfactants makes them a promising tool for biomedical applications . Given the known specific toxic and stress effects of some preparations of cationic nanoparticles, th
Autor:
Ernest Dodoo, Georges Sinclair, Davide Valentini, Elisabeth Sandberg, Inti-Harvey Peredo, Qingda Meng, Jiri Bartek, Xiaohua Luo, Liu Zhenjiang, Martin Rao, Esther Schoutrop, Markus Maeurer, Thomas Poiret, Anna von Landenberg
Publikováno v:
EBioMedicine
EBioMedicine, Vol 23, Iss C, Pp 20-24 (2017)
EBioMedicine, Vol 23, Iss C, Pp 20-24 (2017)
Background Patients with advanced malignancies, e.g. lung cancer, ovarian cancer or melanoma, frequently present with brain metastases. Clinical presentation and disease progression of cancer is in part shaped by the interaction of the immune system
Autor:
Thomas B.K. Watkins, Emilia L. Lim, Selvaraju Veeriah, István Csabai, Maria Greco, Nicholas McGranahan, Gareth A. Wilson, Stefan Boeing, Zoltan Szallasi, Jiri Bartek, Dhruva Biswas, Dijana Djureinovic, Maise Al Bakir, Allan Hackshaw, Charles Swanton, Christopher Abbosh, Rachel Rosenthal, Crispin T. Hiley, Javier Herrero, Krisztián Papp, Kevin Litchfield, Patrick Micke, Judit Moldvay, Balazs Dome, Arul M. Chinnaiyan, Yin Wu, Linnea La Fleur, Marcin Skrzypski, János Fillinger, Mariam Jamal-Hanjani, Marcin Krzystanek, Johan Botling, Nicolai Juul Birkbak, David Allan Moore, Hans Brunnström
Publikováno v:
Biswas, D, Birkbak, N J, Rosenthal, R, Hiley, C T, Lim, E L, Papp, K, Boeing, S, Krzystanek, M, Djureinovic, D, La Fleur, L, Greco, M, Döme, B, Fillinger, J, Brunnström, H, Wu, Y, Moore, D A, Skrzypski, M, Abbosh, C, Litchfield, K, Al Bakir, M, Watkins, T B K, Veeriah, S, Wilson, G A, Jamal-Hanjani, M, Moldvay, J, Botling, J, Chinnaiyan, A M, Micke, P, Hackshaw, A, Bartek, J, Csabai, I, Szallasi, Z, Herrero, J, McGranahan, N, Swanton, C & TRACERx Consortium 2019, ' A clonal expression biomarker associates with lung cancer mortality ', Nature Medicine, vol. 25, no. 10, pp. 1540-1548 . https://doi.org/10.1038/s41591-019-0595-z
An aim of molecular biomarkers is to stratify patients with cancer into disease subtypes predictive of outcome, improving diagnostic precision beyond clinical descriptors such as tumor stage1. Transcriptomic intratumor heterogeneity (RNA-ITH) has bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2225be7c4547fd49cd0909f53c27198
https://pure.au.dk/portal/da/publications/a-clonal-expression-biomarker-associates-with-lung-cancer-mortality(a2adabfd-14ed-486e-b04b-03d3515e134f).html
https://pure.au.dk/portal/da/publications/a-clonal-expression-biomarker-associates-with-lung-cancer-mortality(a2adabfd-14ed-486e-b04b-03d3515e134f).html
Autor:
Jiri Bartek, Jana Símová, Romana Mikyšková, Lenka Kyjacova, Terezie Imrichova, Olena Sapega, Jana Bieblová, Marie Indrová, Zdenek Hodny, Ivan Stepanek, Milan Reiniš, Jan Bubenik
Publikováno v:
Oncotarget
// Jana Simova 1 , Olena Sapega 1 , Terezie Imrichova 2 , Ivan Stepanek 1 , Lenka Kyjacova 2 , Romana Mikyskova 1 , Marie Indrova 1 , Jana Bieblova 1 , Jan Bubenik 3 , Jiri Bartek 2, 4, 5 , Zdenek Hodny 2 , Milan Reinis 1 1 Immunology Unit, Czech Cen
Publikováno v:
British journal of haematology. 184(2)