Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Nadine Spielmann"'
Autor:
Juan Antonio Aguilar-Pimentel, Thomas Klopstock, Eckhard Wolf, Carsten B. Schmidt-Weber, Julia Calzada-Wack, Ralph Fingerhut, Lore Becker, Marie Lucienne, Valerie Gailus-Durner, D. Sean Froese, Nadine Spielmann, Wolfgang Wurst, Philipp Mayer-Kuckuk, Birgit Rathkolb, Lillian Garrett, Martin Hrabě de Angelis, Déborah Mathis, Jan Rozman, Matthias R. Baumgartner, Merima Forny, Dirk H. Busch, Irina Treise, Patricia da Silva-Buttkus, Helmut Fuchs, Oana V. Amarie, Sabine M. Hölter
Publikováno v:
Biochimica et biophysica acta / Molecular basis of disease 1866(3), 165622 (2020). doi:10.1016/j.bbadis.2019.165622
Biochim. Biophys. Acta-Mol. Basis Dis. 1866:165622 (2020)
Biochim. Biophys. Acta-Mol. Basis Dis. 1866:165622 (2020)
Isolated methylmalonic aciduria (MMAuria) is primarily caused by deficiency of methylmalonyl-CoA mutase (MMUT or MUT). Biochemically, MUT deficiency results in the accumulation of methylmalonic acid (MMA), propionyl-carnitine (C3) and other metabolit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3c74a41bb0ba27f5045f882d95511bc
Autor:
Nadine Spielmann, Rohollah Babaei, Adrian T. Billeter, Lars Ketscher, Jorge L. Ruas, Tjeerd P. Sijmonsma, Gretchen Wolff, Jan Gronych, Martin Hrabé de Angelis, Alexandros Vegiopoulos, Mathias Heikenwalder, Damir Krunic, Maximilian Schuster, Stephan Herzig, Irem Bayindir-Buchhalter, Beat P. Müller-Stich, Peter Lichter, Sarah Lerch
Publikováno v:
EMBO Molecular Medicine
EMBO Mol. Med. 10:e8613 (2018)
EMBO Molecular Medicine, Vol 10, Iss 8, Pp n/a-n/a (2018)
EMBO Mol. Med. 10:e8613 (2018)
EMBO Molecular Medicine, Vol 10, Iss 8, Pp n/a-n/a (2018)
Most antidiabetic drugs treat disease symptoms rather than adipose tissue dysfunction as a key pathogenic cause in the metabolic syndrome and type 2 diabetes. Pharmacological targeting of adipose tissue through the nuclear receptor PPARg, as exemplif