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Publikováno v:
BMJ case reports. 14(7)
Immune checkpoint inhibitors (ICIs) are associated with a variety of immune-related adverse events (irAEs), but haematological irAEs are rare. We report a case of presumed complement-mediated thrombotic microangiopathy (CM-TMA) in a 78-year-old man w
Publikováno v:
Nutr Neurosci
Diets high in saturated fat (HFD) disrupt dopamine neurotransmission, whereas fasting alters tonic and phasic dopamine release to drive motivation and food consumption. However, functional compartments in the nucleus accumbens (NAc) influencing these
Autor:
Mª Queralt Gorgas, Benito Almirante, Alfonso Ayora, Andrés Antón, Juliana Esperalba, Xavier Vidal, Cristina Aguilera, Esteban Ribera, Manuel Alonso, Antònia Agustí, Elena Guillén, Meritxell Espuga, Cristina Andrés
Publikováno v:
Enfermedades Infecciosas y Microbiología Clínica
Enfermedades Infecciosas Y Microbiologia Clinica
Enfermedades Infecciosas Y Microbiologia Clinica
Objectives To assess the efficacy and safety of hydroxychloroquine (HCQ) compared with no treatment in healthcare workers with mild SARS-CoV-2 infection. Methods Prospective, non-randomized study. All health professionals with confirmed COVID-19 betw
Autor:
Chim C. Lang, Jasper Tromp, R. A. de Boer, Peter van der Meer, Kenneth Dickstein, Adriaan A. Voors, Marco Metra, George Markousis-Mavrogenis, Dirk J. van Veldhuisen, Wouter Ouwerkerk, S.D. Anker, Joao Pedro Fereirra, Nilesh J. Samani, John G.F. Cleland, Gerasimos Filippatos
Publikováno v:
Cardiovascular Research (CVR)
Cardiovascular Research, 118(8), 1964-1977. Oxford University Press
Cardiovascular research, 118(8), 1964-1977. Oxford University Press
Cardiovascular Research, 118(8), 1964-1977. Oxford University Press
Cardiovascular research, 118(8), 1964-1977. Oxford University Press
Aims The exploration of novel immunomodulatory interventions to improve outcome in heart failure (HF) is hampered by the complexity/redundancies of inflammatory pathways, which remain poorly understood. We thus aimed to investigate the associations b
Publikováno v:
BMJ Case Rep
Statin-induced necrotising autoimmune myopathy (SINAM), a rare complication of statin use, presents with significant proximal muscle weakness and raised creatine kinase (CK) levels (50–100 times). This is different from other musculoskeletal condit
Publikováno v:
BMJ Case Rep
This case report describes a young man with a history of lymphoedema and long-standing gastrointestinal symptoms since childhood. After undergoing extensive investigations, he was diagnosed with primary intestinal lymphangiectasia (IL). The patient
Autor:
Abdulrazaq Bidemi Nafiu, Abdulbasit Amin, Bamidele Victor Owoyele, Adedamola Bayo-Olugbami, Olalekan M. Ogundele, Charles C. Lee
Publikováno v:
Nutr Neurosci
BACKGROUND: L-DOPA, the predominant therapy for Parkinson’s disease (PD) is associated with motor deficits after prolonged use. The nigrostriatal tract, a primary target of neurodegeneration in PD, contains abundant Vitamin-D receptors, suggesting
Publikováno v:
Biomedical Journal. 45:387-395
Background Nitrite stimulates insulin secretion from pancreatic β-cells; however, the underlying mechanisms have not been completely addressed. The aim of this study is to determine effect of nitrite on gene expression of SNARE proteins involved in
Publikováno v:
Journal of Clinical Densitometry. 25:223-229
The aim of the study was to determine the effect of pregabalin as monotherapy on biochemical markers and bone mineral density. 40 patients diagnosed with neuropathic pain or fibromyalgia syndrome who were using pregabalin for at least 6 months and ag
Autor:
Tzu-Chan Wu, Wen-Long Hu, Yu-Chiang Hung, Chun-Ting Liu, Meng-Chang Tsai, Szu-Ying Wu, Chun-En Kuo
Publikováno v:
Biomedical Journal. 45:414-423
The incidence of opioid use disorder (OUD) is increasing worldwide, and the opioid-related overdose crisis is currently a major global challenge. This study investigated the effects of adjuvant laser meridian massage (LMM) in men with OUD undergoing