Zobrazeno 1 - 6
of 6
pro vyhledávání: '"David L. Huso"'
Publikováno v:
Blood. 131:323-327
The stromal signals that promote B lymphopoiesis remain poorly understood. Hedgehog (Hh) signaling promotes B lymphopoiesis in a non-cell-autonomous fashion in vitro, and depletion of the Hh effector Smoothened (Smo) from stromal cells is associated
Autor:
Michael Koo, James Turkson, David L. Huso, Tait Huso, Patrick T. Gunning, Lingling Xian, Guosheng Liu, Brent D. G. Page, Amy Belton, Li Z. Luo, Linda M.S. Resar
Publikováno v:
Leukemia & Lymphoma. 57:2681-2684
Despite dramatic improvements in treatment and survival, acute lymphoid malignancies remain the leading cause of death in children with cancer and a highly lethal malignancy in adults.[1] Acute lym...
Autor:
Robert A. Casero, Franck Housseau, Cynthia L. Sears, Sara W. Van Meerbeke, David L. Huso, Christina E. DeStefano Shields, Hao Wang, Heather M. O'Hagan
BACKGROUND Chronic inflammation and composition of the colon microbiota have been associated with colorectal cancer in humans. The human commensal enterotoxigenic Bacteroides fragilis (ETBF) is linked to both inflammatory bowel disease and colorectal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62ad187a1d4759ea3cb2aae9338cc5b
https://europepmc.org/articles/PMC4907405/
https://europepmc.org/articles/PMC4907405/
Autor:
Jamunarani Vadivelu, David L. Huso, Ausama A. Malik, Elizabeth C. Wick, Kellie N. Smith, Jane W. Wanyiri, Drew M. Pardoll, Cynthia L. Sears, Shaoguang Wu, Sudipto Ganguly, Nicolas J. Llosa, Ada Tam, Hongni Fan, Franck Housseau, Sara W. Van Meerbeke, April Camilla Roslani, Xinqun Wu, Thevambiga Iyadorai
IL17-producing Th17 cells, generated through a STAT3-dependent mechanism, have been shown to promote carcinogenesis in many systems, including microbe-driven colon cancer. Additional sources of IL17, such as γδ T cells, become available under infla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87717b07cd19af2a98a001e5904f8520
https://europepmc.org/articles/PMC4873376/
https://europepmc.org/articles/PMC4873376/
Autor:
Hongni Fan, Cynthia L. Sears, Christine M. Dejea, Shaoguang Wu, Benjamin B. Finard, Abby L. Geis, Xinqun Wu, Christina E. DeStefano Shields, David L. Huso, Elizabeth C. Wick, Kai Fu, June L. Chan, Ada J. Tam, Sara W. Van Meerbeke, Liam Chung, Fengyi Wan, Florencia McAllister, Erik Thiele Orberg, Payam Fathi, Andriana Lebid, Franck Housseau, Drew M. Pardoll, Jie Chen, Paul Metz, Sudipto Ganguly
Publikováno v:
Cell host & microbe, vol 23, iss 2
Summary Pro-carcinogenic bacteria have the potential to initiate and/or promote colon cancer, in part via immune mechanisms that are incompletely understood. Using Apc Min mice colonized with the human pathobiont enterotoxigenic Bacteroides fragilis
Publikováno v:
Blood. 128:2647-2647
Introduction: Nuclear chromatin structure is a key determinant of stem cell function and cell fate, although factors that regulate this are only beginning to emerge. While High Mobility Group A1(HMGA1) chromatin remodeling proteins are among the most