Zobrazeno 1 - 10
of 103
pro vyhledávání: '"621"'
Autor:
Katharine Y. Zhang, Alana De Luca, Bingyang Shi, Adam K. Walker, Justin J. Yerbury, Julie D. Atkin, Marco Morsch, Kelly L. Williams, Stephanie L. Rayner, Shu Yang, Albert Lee, Roger S. Chung, Mark P. Molloy, Hamideh Shahheydari, Ian P. Blair, Vinod Sundaramoorthy, Nicholas J. Cole, Audrey Ragagnin, Serene S. L. Gwee, Emily K. Don
Publikováno v:
Open Biology
Open Biology, Vol 7, Iss 10 (2017)
Open Biology, Vol 7, Iss 10 (2017)
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder that is characterized by progressive weakness, paralysis and muscle loss often resulting in patient death within 3–5 years of diagnosis. Recently, we identified disease-linke
Autor:
Parmvir K. Bahia, Thomas A. Parks, David A. Mitchell, Thomas E. Taylor-Clark, Stanley M. Stevens, Sameer Varma, Katherine R. Stanford
Publikováno v:
The Journal of General Physiology
Electrophiles produced during oxidative stress trigger pain responses by reacting with TRPA1 ion channels on sensory nerves. Bahia et al. show that residue C621 on TRPA1 has remarkable reactivity with electrophiles—more than cellular antioxidants
Autor:
Rohann J.M. Correa, Dorien Autaers, Jan Jonckheere, Louise Cras, Keith Kwan, Kris Thielemans, Hanne Locy, Marian Vanhoeij, Stefanie Brock, Stefaan Verhulst, Karine Breckpot, A. Schiettecatte, Wim Waelput
Publikováno v:
Biomolecules
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 621, p 621 (2021)
Volume 11
Issue 5
Biomolecules, Vol 11, Iss 621, p 621 (2021)
The use of gene expression profiling (GEP) in cancer management is rising, as GEP can be used for disease classification and diagnosis, tailoring treatment to underlying genetic determinants of pharmacological response, monitoring of therapy response
Autor:
Rachel S. Kelly, Natalia Palacios, Katherine L. Tucker, Tammy Scott, Sherman J Bigornia, Jong Soo Lee, Shilpa N Bhupathiraju
Publikováno v:
J Alzheimers Dis
BACKGROUND: Minorities, including mainland Puerto Ricans, are impacted disproportionally by Alzheimer’s disease (AD), dementia, and cognitive decline. Studying blood metabolomics in this population has the potential to probe the biological underpin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd763f752e84026e3dad8420eac84ed0
https://europepmc.org/articles/PMC8061579/
https://europepmc.org/articles/PMC8061579/
Autor:
Susan T. Mayne, Rachael Z. Stolzenberg-Solomon, Melinda L. Irwin, Robert N. Hoover, Steven C. Moore, Mary C. Playdon, Henry J. Thompson, Regina G. Ziegler, Joshua N. Sampson
Publikováno v:
The American Journal of Clinical Nutrition. 106:637-649
Background: The epidemiologic evidence for associations between dietary factors and breast cancer is weak and etiologic mechanisms are often unclear. Exploring the role of dietary biomarkers with metabolomics can potentially facilitate objective diet
Autor:
Mauricio Calderon, Alren O. Vandy, Mukesh Prajapati, Mohamed Vandi, Hamish Mohammed, David Otieno, Rebecca Stretch
Publikováno v:
Emerging Infectious Diseases
Emerging Infectious Diseases, Vol 23, Iss 1, Pp 66-73 (2017)
Emerging Infectious Diseases, Vol 23, Iss 1, Pp 66-73 (2017)
We rapidly assessed the health of Ebola virus disease (EVD) survivors in Kenema, Sierra Leone, by reviewing medical charts of all patients attending the Survivor Clinic of Kenema Government Hospital. Data were abstracted on signs and symptoms at ever
Autor:
Pritam Sinharoy, Daniel J. DelloStritto, Holly C. Cappelli, Ian N. Bratz, Derek S. Damron, Werner J. Geldenhuys, Patrick J. Connell, Charles K. Thodeti, Joseph N. Fahmy
Publikováno v:
Free Radical Biology and Medicine. 101:10-19
We demonstrated previously that TRPV1-dependent regulation of coronary blood flow (CBF) is disrupted in diabetes. Further, we have shown that endothelial TRPV1 is differentially regulated, ultimately leading to the inactivation of TRPV1, when exposed
Publikováno v:
Reproductive Biology and Endocrinology, Vol 17, Iss 1, Pp 1-7 (2019)
Reproductive Biology and Endocrinology : RB&E
Reproductive Biology and Endocrinology : RB&E
The objective of this systematic review was to examine the literature and to compare the effectiveness of letrozole (LE) versus laparoscopic ovarian drilling (LOD) for the induction of ovulation in women with clomiphene citrate (CC)-resistant polycys
Elevated body mass index (BMI) is associated with increased risk of postmenopausal breast cancer. The underlying mechanisms, however, remain elusive.In a nested case-control study of 621 postmenopausal breast cancer case participants and 621 matched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1ed63a6a5e8e1d27efc7953220c7a0
https://europepmc.org/articles/PMC6279286/
https://europepmc.org/articles/PMC6279286/
Autor:
Masood Abu-Halima, Sigrun Nestel, Claudia Staib, Andreas Keller, Irina Nazarenko, Tobias Fehlmann, Eckart Meese, Sebastian Häusler, Christina Backes
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
MicroRNAs (miRNAs) are class of small RNA molecules with major impact on gene regulation. We analyzed the potential of miRNAs secreted from pre-implantation embryos into the embryonic culture media as biomarkers to predict successful pregnancy. Using