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Autor:
François Pinquie, Alain Morel, Benjamin Morvan, Jérémy Sandrini, Olivier Molinier, Alexis B. Cortot, Camille Guguen, Louise-Marie Chevalier
Publikováno v:
Clinical Lung Cancer. 23:e131-e134
Clinical Practice Points • What is already known about this subject? • Resistance mechanisms to osimertinib in T790M positive NSCLC patients are multiple and heterogeneous, combining de novo EGFR alterations (C797S mutation), EGFR-independent mec
Autor:
Daniel M. Berney, Jonathan Shamash, T. Oliver, Anju Sahdev, S. J. Harland, Andrew Gogbashian, Constantine Alifrangis, Gordon J. S. Rustin, Samita Agarwal, Marina Milic, Sarah Duncan, Sara Stoneham, Shafi Chowdhury, Anand Sharma, Michelle Lockley, Peter Wilson
Publikováno v:
European Journal of Cancer. 164:105-113
Background Radiotherapy and cisplatin-based combination chemotherapy are accepted standard-of-care treatments for metastatic seminoma with excellent survival outcomes but with established short- and long-term morbidity. Carboplatin monotherapy may be
Publikováno v:
BMJ Case Rep
A 75-year-old man was admitted with a 3-month history of worsening diarrhoea and weight loss. He was on long-term immunosuppression following cardiac transplantation. Investigations revealed herpes simplex oesophagitis and stool samples were positive
Autor:
Louis B. Nabors, David A. Reardon, John Simes, Lisa Roberts-Rapp, Ho-Jin Lee, Nicholas Butowski, Tobias Walbert, Andrew B. Lassman, Helen Wheeler, Priya Kumthekar, Andrew M. Scott, Peter Ansell, Tom Mikkelsen, Marta Penas-Prado, Kyriakos P. Papadopoulos, Martin J. van den Bent, Earle Bain, Zarnie Lwin, Erica Gomez, David Maag, Ryan Merrell, Hui K Gan, Hao Xiong, Kyle D. Holen
Publikováno v:
Cancer Chemotherapy & Pharmacology, 80(6), 1209-1217. Springer-Verlag
Cancer Chemotherapy and Pharmacology
Cancer Chemotherapy and Pharmacology
Purpose Patients with recurrent glioblastoma (rGBM) have a poor prognosis. Epidermal growth factor receptor (EGFR) gene amplification is present in ~ 50% of glioblastomas (GBMs). Depatuxizumab mafodotin (depatux-m), formerly ABT-414, is an antibody
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff65c6833473b7cdb380bda35882ca5
Publikováno v:
BMJ Case Rep
A 55-year-old male presented to our emergency department with haematuria and abdominal pain. Investigations including a computed tomography (CT) scan revealed an intraluminal filling defect within the left collecting system, consistent in appearance
Autor:
Scott A. Beatson, Emma Ballard, David M. Whiley, Bryan A. Wee, Laura J. Sherrard, Hanna E. Sidjabat, Keyur A. Dave, Kay A. Ramsay, Keith Grimwood, Scott C. Bell, C. Duplancic, Claire E. Wainwright, Timothy J. Kidd
Publikováno v:
Journal of Cystic Fibrosis. 21:e35-e43
Background: Antimicrobial resistance in cystic fibrosis (CF) Pseudomonas aeruginosa airway infection is complex and often attributed to chromosomal mutations. How these mutations emerge in specific strains or whether particular gene mutations are cli
Autor:
Gulbu Uzel, Hye Sun Kuehn, Christina Tatsi, Thomas A. Fleisher, Yan Su, Julie E. Niemela, Jennifer Stoddard, Maya Lodish, Sergio D. Rosenzweig, Warren J. Leonard, Constantine A. Stratakis, SuJin Hwang, Rosanne Spolski, Steven M. Holland
Publikováno v:
J Allergy Clin Immunol
BACKGROUND: Pediatric endogenous Cushing syndrome is mainly caused by pituitary corticotropin-producing adenomas and most glucocorticoid-dependent effects progressively regress upon tumor removal. Endogenous Cushing syndrome reproduces long-term high
Autor:
Gina Amanda, Wisnu Tafroji, Budi Haryanto, Dianiati Kusumo Sutoyo, Dodi Safari, Erlina Burhan
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 6, Pp 1175-1178 (2021)
Streptococcus pneumoniae is one of the primary causes of community-acquired pneumonia. The vaccine serotypes were dominant and could be isolated in 14% of adult patients, with serotype 3 being the most predominant (25%), followed by 6A, 6B, and 7F. A
Autor:
Kenji Kishimoto, Kunihiko Kobayashi, Daisuke Suzuki, Hirozumi Sano, Satoru Matsushima, Ryoji Kobayashi, Daiki Hori
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 6, Pp 1056-1060 (2021)
Background: Antibiotics have been widely and efficaciously used for febrile neutropenia in pediatric patients. However, reports are scant regarding the risk factors for recurrent fever after discontinuation of antibiotics in a neutropenic state. Here
Autor:
Chia Yu Chi, Ching Chuan Liu, Ching Fen Shen, Pei Jane Tsai, Jiunn Jong Wu, Wei Chun Tsai, Fan Ching Shen, Ya Lan Lin, Yee Shin Lin, Shuying Wang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 6, Pp 1086-1093 (2021)
Background: Group A Streptococcus (GAS) is an important pathogen causing morbidity and mortality worldwide. Surveillance of resistance and emm type has important implication to provide helpful information on the changing GAS epidemiology and empirica