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Publikováno v:
BMJ Case Rep
A 75-year-old woman was diagnosed with primary idiopathic thrombocytopenic purpura (ITP). The patient had no history of thrombotic events. We could not administer the standard dose of glucocorticoid because of her old age, and her platelet count did
Autor:
Rong-Chi Huang, Hsin-Yi Lin
Publikováno v:
Biomedical Journal. 45:143-154
Background The central clock of the suprachiasmatic nucleus (SCN) controls the metabolism of glucose and is sensitive to glucose shortage. However, it is only beginning to be understood how metabolic signals such as glucose availability regulate the
Publikováno v:
Nutr Neurosci
High-fat diets are linked with obesity and changes in dopamine neurotransmission. Mounting evidence shows that saturated fat impacts dopamine neurons and their terminal fields, but little is known about the effect a diet high in unsaturated fat has o
Autor:
Gianmarco Bellucci, Ferdinando Nicoletti, Marika Alborghetti, Diego Centonze, Chiara Calderoni, Marco Salvetti, Antonietta Gentile, Ruggero Capra
Publikováno v:
Current Neuropharmacology. 20:107-125
Since COVID-19 has emerged as a word public health problem, attention has been focused on how immune suppressive drugs used for the treatment of autoimmune disorders influence the risk for SARS-CoV-2 infection and the development of the acute respira
Publikováno v:
Biomedical Journal. 44:694-708
Background Pancreatic cancer is one of the most notorious cancers and is known for its highly invasive characteristics, drug resistance, and metastatic progression. Unfortunately, resistance towards gemcitabine develops in many with advanced pancreat
Autor:
Dania Cheaha, Chatchai Wattanapiromsakul, Nifareeda Samerphob, Ekkasit Kumarnsit, Rodiya Manor, Nusaib Sa-ih, Acharaporn Issuriya, Jackapun Kwangjai
Publikováno v:
Biomedical Journal. 44:727-738
Background Citrus essential oil (EO) has been used for mood elevation and sedative hypnotic purposes. However, scientific proofs of its central nervous system (CNS) action remained largely unexplored. This study investigated chemotypes, electrical br
Autor:
Bianca de Oliveira Alves, Mikaela Scatolin, João G.G. Guzatti, Jacir Dal Magro, Jean Felipe Fossá Calisto, J. Vladimir Oliveira, Rafael Martello, Letícia V. Morgan, Maryelen A. Souza, Monica S.Z. Schindler, Liz Girardi Müller, Jaqueline Scapinello
Publikováno v:
Biomedical Journal. 44:S63-S72
Background A. gratissima is a shrub used in folk medicine as analgesic and sedative. However, studies on its antinociceptive activity are scarce. This research aimed to evaluate the antinociceptive effect of a supercritical carbon dioxide (SCCO2) ext
Autor:
Michael J. Vjecha, Alimuddin Zumla, Giovanni Battista Migliori, Jessica Galvin, Adam Zumla, Simon Tiberi
Publikováno v:
International Journal of Infectious Diseases
International Journal of Infectious Diseases, Vol 113, Iss, Pp S96-S99 (2021)
International Journal of Infectious Diseases, Vol 113, Iss, Pp S96-S99 (2021)
The WHO 2020 global TB Report estimates that in 2019 there were an estimated 500,000 cases of multi-drug resistant TB (MDR-TB) of which only 186,772 MDR-TB cases were diagnosed, and positive treatment outcomes were achieved in 57% of them. These data
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 6, Pp 1118-1121 (2021)
Background Arbekacin is a broad-spectrum aminoglycoside with activity against some Gram-positive and Gram-negative bacteria. Methods Arbekacin minimum inhibitory concentration (MIC) values were determined for 296 drug-resistant Gram-negative bacilli,
Autor:
Jin-Yuan Wang, Li-Min Huang, Fu-Yuan Huang, Hsin Chi, Ching-Ying Huang, Yi-Hsuan Tu, Chien-Wei Lee, Nan-Chang Chiu, Yu-Lin Tai, Daniel Tsung-Ning Huang
Publikováno v:
Journal of Microbiology, Immunology and Infection, Vol 54, Iss 5, Pp 876-884 (2021)
Purpose This study aimed to compare the safety and efficacy of clarithromycin-naproxen-oseltamivir combination therapy to that of oseltamivir therapy alone in hospitalized pediatric influenza patients. Methods This prospective, single-blind study inc