Zobrazeno 1 - 10
of 412
pro vyhledávání: '"Hua Zhang"'
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 38:122-131
Background: Gastric cancer (GC) is a common tumor found worldwide, and cisplatin is the first-line agent for the treatment of GC. However, the resistance to cisplatin is an obstacle. Here, we aim to explore the biological mechanism of long noncoding
Autor:
Zhongliang Guo, Jian Fang, Junhong Zhang, Puyuan Xing, Xiaoli Zhu, Changlu Hu, Yuming Jia, Ming Zhou, Zhiwei Lu, Bin Wang, Ke Wang, Yiping Zhang, Lin Wu, Zhanyu Pan, Yanju Chen, Junquan Yang, Shuhua Han, Yongqian Shu, Lianke Liu, Bingqiang Ni, Yong Liu, Hongming Pan, Rongyu Liu, Shengming Liu, Qian Sun, Feng Ye, Qinhong Zheng, Guojun Zhang, Tiegang Tang, Tianjiang Ma, Jianyong Zhang, Bo Jiang, Mafei Kang, Zhiguo Luo, Wenjuan Lian, Can Wu, Lijun Ma, Zhiyong He, Wensheng Qiu, Dongqing Lv, Zheng Liu, Qisen Guo, Dedong Wu, Ke Xiao, Xia Yuan, Jun Chen, Yan Yu, Yuankai Shi, Guolei Wang, Dongji Chen, Shuyang Zhu, Jianhua Shi, Guolong Liu, Hua Zhang, Hongbing Duan, Bo Qiu, Wangjun Liao, Shumin Wang, Jinsheng Shi, Tienan Yi, Hong Lu, Xueli Yuan, Emei Gao, Yimin Mao, Xicheng Wang, Li Zhao, Xiaohong Wu, Yanqiu Zhao, Yan Wang, Kaijian Lei, Yinghua Ji, Yulong Zheng, Minghong Bi, Manxiang Li, Debin Sun, Yuan Chen
Publikováno v:
Cancer Communications, Vol 41, Iss 9, Pp 889-903 (2021)
Cancer Communications
Cancer Communications
Background Previous studies have demonstrated the preclinical pharmacological and toxicological consistency, and clinical pharmacokinetic equivalence of bevacizumab biosimilar LY01008 with reference bevacizumab (Avastin). This randomized controlled t
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 22, Iss, Pp 1142-1153 (2020)
Molecular Therapy: Nucleic Acids, Vol 22, Iss, Pp 1142-1153 (2020)
Dysregulated expression of microRNAs (miRNAs or miRs) has been implicated in the pathophysiology of type 2 diabetes mellitus (T2DM). However, their underlying role in the complication of detrusor fibrosis remains poorly understood. Therefore, this st
Autor:
Yan-Hong Li, Hua Zhang, Zhong Tingying, Tang Jun, Gai-Fang Yao, Xiao-Yan Chen, Zhong-Qin Huang, Ting-Ting Li, Kang-Di Hu, Sha-Sha Wang, Ke-Ke Sun, Feng Yang, Lan-Ying Hu
Publikováno v:
Journal of Plant Growth Regulation. 40:2548-2559
As a signaling molecule, hydrogen sulfide (H2S) plays an indispensable role in the modulation of ripening and senescence in fruits and vegetables. To explore the role of H2S in regulating metabolism of postharvest tomato, ripening-related physiologic
Autor:
Hua Zhang, Yifan Zhang, Xiao-yun Liu, Jing-Jing Bao, Liyan Miao, Zhendong Chen, Yong Jiang, Dafang Zhong, Jian Meng
Publikováno v:
Acta Pharmacol Sin
Furmonertinib was designed for the treatment of non-small cell lung cancer (NSCLC) patients with EGFR T790M mutation. In this study, we investigated the metabolic disposition and mass balance in humans and tissue distribution in rats. After a single
Autor:
Yan-Yan Chen, Hua Zhang, Zhi-Qiang Liu, Jun-Ting Fan, Hou-Wen Lin, Tian-Yong Hu, Wei-Hua Jiao, Bao-Hui Cheng
Publikováno v:
Journal of Inflammation Research
Tian-Yong Hu,1,* Hua Zhang,1,* Yan-Yan Chen,1 Wei-Hua Jiao,2 Jun-Ting Fan,3 Zhi-Qiang Liu,1 Hou-Wen Lin,2 Bao-Hui Cheng1 1Shenzhen Key Laboratory of ENT, Institute of ENT and Longgang ENT Hospital, Shenzhen, 518172, People’s Republic of China; 2Res
Autor:
Wei-Yue Liang, Ying-Hua Zhang, Yu-Tang Wang, Qing Yuan, Bao-Long Feng, Jia-Yi Yin, Qian Zhou, Dong-Mei Chen
Publikováno v:
Food & Function. 12:1580-1589
Gout is a common inflammatory arthritis associated with various comorbidities, such as cardiovascular disease and metabolic syndrome. Xanthine oxidase inhibitors (XOIs) have emerged as effective substances to control gout. Much attention has been giv
Publikováno v:
Food & Function. 12:3705-3719
Similar to other food contaminants, dietary oxidized soybean oil (OSO) is also a toxic xenobiotic for animal and human nutrition. This research evaluated the effects of maternal OSO exposure during lactation on mammary mitochondrial injury and intest
Autor:
Chuanlei Yang, Jie Xiao, Xinzhong Chen, Yang Li, Jinping Liu, Hua Zhang, Xing Zi Chen, Zhanjie Wei, Weiqiang Chen
Publikováno v:
Drug Design, Development and Therapy. 14:5547-5558
Background Acute lung injury (ALI) is a fatal disease in the absence of pharmacological treatment. Oxidative stress and inflammation are closely related to ALI. Innate immune cells are the main source of reactive oxygen species (ROS). Macrophages pla
Autor:
Hui-En Wang, Wenfei Xue, Qingtao Zhao, Xiaopeng Zhang, Zhonghui Hu, Guo-Chen Duan, Wenbo Wu, Hua Zhang, Lei Yu
Publikováno v:
OncoTargets and therapy
Purpose To study the effect of β-elemene on the radiosensitivity of A549 cell xenograft tumor and potential mechanisms by which β-elemene regulates the expression of hypoxia-inducible factor-1α (HIF-1α) and glucose transporter protein-1 (GLUT-1).