Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Hua Zhang"'
Autor:
Jia-Nan Zhu, Chang Chen, Philip N. Baker, Ting-Li Han, Wei Zhou, Hua Zhang, Hao Chen, Xin Tang
Publikováno v:
Journal of Cellular and Molecular Medicine
The forkhead box O3a protein (FoxO3a) has been reported to regulate tumour invasion and migration, but little is known about the molecular mechanism or its role in trophoblast invasion and migration into the uterus. In this study, we aim to explore i
Autor:
Hailong Wang, Rui Zhang, Yue Xu, Zhenfa Zhang, Shilei Xu, Bin Zhang, Changli Wang, Yulong Chen, Sha Yongsheng, Hua Zhang, Xiaoliang Zhao, Yuan Wang, Jianquan Zhu, Lianmin Zhang
Publikováno v:
Thoracic Cancer, Vol 12, Iss 9, Pp 1291-1302 (2021)
Thoracic Cancer
Thoracic Cancer
Background CITED4 belongs to the CBP/p300‐interacting transactivator with glutamic acid and aspartic acid‐rich tail (CITED) family which is induced by various cytokines and participates in cytokine‐induced proliferation and differentiation. CIT
Publikováno v:
Human Cell. 33:737-749
Bladder cancer (BCa) is one of the most common urinary malignancies in the world. Growing evidence suggests that epithelial-to-mesenchymal transition (EMT) is a major contributor for BCa metastasis. lncRNA small nucleolar RNA host gene 16 (SNHG16) ha
Autor:
Huan Wang, Jin-Cheng Guo, Yuhualei Pan, Jian-Hua Zhang, Yanbing Zhu, Song Wang, Yushang Zhao, Lianhe Zhao, Shaoxin Tao
Publikováno v:
Journal of Cellular Biochemistry. 121:3593-3605
Glioblastoma multiforme (GBM) is a highly malignant brain tumor. We explored the prognostic gene signature in 443 GBM samples by systematic bioinformatics analysis, using GSE16011 with microarray expression and corresponding clinical data from Gene E
Publikováno v:
European Journal of Histochemistry, Vol 65, Iss 3 (2021)
European Journal of Histochemistry : EJH
European Journal of Histochemistry : EJH
The aim of this study was to explore the effects of the lncRNA ENST00000623984 on colorectal cancer. In this study, the expression levels of ENST000000623984 were first examined in tumor tissue and adjacent normal tissue from 40 patients with colorec
Autor:
Yamin Liu, Chao Tong, Yuxiang Bai, Chengyu Huang, Yubin Ding, Chen Zhang, Lei Li, Yuxin Ran, Philip N. Baker, Hao Wang, Hua Zhang, Li Wen, Xuehai Chen, Bin Tan, Jianlin Zhao, Hongbo Qi, Xiaofang Luo, Wei Peng
Publikováno v:
The FASEB Journal. 33:6327-6338
Successful pregnancy requires normal placentation, which largely depends on the tight regulation of proliferation, invasion, and migration of trophoblast cells. Abnormal functioning of trophoblast cells may cause failure of uterine spiral artery remo
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 28:3693-3699
Protein arginine methyltransferase 5 (PRMT5) is an epigenetics related enzyme that has been validated as a promising therapeutic target for human cancer. Up to now, two small molecule PRMT5 inhibitors has been put into phase I clinical trial. In the
Autor:
Hua Zhang, Hua Xie, Hongxing Li, Xiaoqun Xu, Yang Su, Guanglin Chen, Zhongxian Zhu, Lei Peng, Weibing Tang, Zechao Wen, Qiyang Shen, Chunxia Du
Publikováno v:
Journal of Cellular Physiology. 234:10576-10587
It has been suggested that circular RNAs play critical roles in natural growth and disease development. Nevertheless, whether the circular RNAs were related in Hirschsprung's disease (HSCR) remains unknown. Thus, we discovered the cir-CCDC66 was down
Publikováno v:
International Journal of Molecular Medicine
Endothelial dysfunction and diabetic vascular disease induced by chronic hyperglycemia involve complex interactions among high glucose, long non-coding RNAs (lncRNAs), microRNAs (miRNAs or miRs) and the Ser/Thr kinase AKT. However, the molecular mech
Autor:
Lin-Quan Tang, Shao-Jun Lin, Ao Zhang, Man-Zhi Li, Sui Jianhua, Li Yuan, Hua Zhang, Li Huiyu, Liu Yanyan, Yu-Ming Zheng, Qian Zhong, Wanli Liu, Zhi-Qiang Ling, Peng Huang, Shi-Bing Li, Yi Xin Zeng, Ming-Fang Ji, Shan Xing, Mu Sheng Zeng, Shuo-Gui Fang
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 9, Pp n/a-n/a (2020)
EMBO Molecular Medicine
EMBO Molecular Medicine
Metabolic reprogramming plays important roles in development and progression of nasopharyngeal carcinoma (NPC), but the underlying mechanism has not been completely defined. In this work, we found INSL5 was elevated in NPC tumor tissue and the plasma