Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Craig J. Goergen"'
Publikováno v:
Frontiers in Cardiovascular Medicine
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Thoracic aortic aneurysm (TAA) is a focal enlargement of the thoracic aorta, but the etiology of this disease is not fully understood. Previous work suggests that various genetic syndromes, congenital defects such as bicuspid aortic valve, hypertensi
Autor:
Craig J. Goergen, Gurneet S Sangha, Matthias Trenner, Andrea Acuna, Lars Maegdefessel, Alycia G. Berman, Hans-Henning Eckstein, Albert Busch, Evan H. Phillips
Publikováno v:
J Vasc Res
Reduced lower-limb blood flow has been shown to lead to asymmetrical abdominal aortic aneurysms (AAAs) but the mechanism of action is not fully understood. Therefore, small animal ultrasound (Vevo2100, FUJIFILM VisualSonics) was used to longitudinall
Angiotensin II Infusion Does Not Cause Abdominal Aortic Aneurysms in Apolipoprotein E-Deficient Rats
Autor:
Tamara L. Kinzer-Ursem, Craig J. Goergen, Mandy S Chang, Evan H. Phillips, Sydney N Gorman, Karin F.K. Ejendal, A Nicole Blaize, Hamna J. Qureshi
The apolipoprotein E-deficient (apoE-/-) mouse model has advanced our understanding of cardiovascular disease mechanisms and experimental therapeutics. This spontaneous model recapitulates aspects of human atherosclerosis, and allows for the developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1659102b7f1edea147ae39323f2891c2
https://europepmc.org/articles/PMC5829005/
https://europepmc.org/articles/PMC5829005/
Publikováno v:
APL Bioengineering, Vol 2, Iss 4, Pp 046106-046106-22 (2018)
APL Bioengineering
APL Bioengineering
We report here on the early pathology of a well-established murine model of dissecting abdominal aortic aneurysms (AAAs). Continuous infusion of angiotensin II (AngII) into apolipoprotein E-deficient mice induces the formation of aortic dissection an
Development and growth trends in angiotensin II-induced murine dissecting abdominal aortic aneurysms
Autor:
Craig J. Goergen, Bruce A. Craig, Amelia R. Adelsperger, Hilda S. Ibriga, Evan H. Phillips, Michael P. Murphy, Linden A. Green
Publikováno v:
Physiological Reports
Abdominal aortic aneurysms are pathological dilations that can suddenly rupture, causing more than 15,000 deaths in the U.S. annually. Current treatment focuses on observation until an aneurysm's size warrants surgical intervention. Thus, there is a