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Autor:
Tatiana Gamez, Carlos Vargas, Christian Rolfo, Pilar Archila, Luis Corrales, Oscar Arrieta, Claudio Martin, Jorge Otero, C. Sotelo, Hernán Carranza, Juan Esteban Garcia-Robledo, D. Mayorga, Luisa Ricaurte, Camila Ordóñez-Reyes, Lucia Zatarain Barron, L. Rojas, Rafael Rosell, Luis Mas, Alejandro Ruiz-Patiño, Maritza Bermudez, July Rodriguez, J. Ávila, Andrés F. Cardona, Gonzalo Recondo, Feliciano Barrón
Publikováno v:
Repositorio U. El Bosque
Universidad El Bosque
instacron:Universidad El Bosque
Universidad El Bosque
instacron:Universidad El Bosque
La activación de BIM es esencial para la apoptosis desencadenada por el inhibidor de la tirosina quinasa (TKI) del receptor del factor de crecimiento epidérmico (EGFR) en el cáncer de pulmón de células no pequeñas (CPCNP) con mutación de EGFR.
Publikováno v:
Japanese Journal of Infectious Diseases. 74:429-436
The domestic combined measles-mumps-rubella (MMR) vaccine was withdrawn in Japan in 1993 following an outbreak of aseptic meningitis attributed to the mumps component of the cocktail. KM-248 is an MMR vaccine (M-M-R®II), manufactured by Merck & Co.,
Autor:
Harry G.M. Heijerman, Renske van der Meer, Jeffrey M. Beekman, Gitte Berkers, Cornelis K. van der Ent, Joshena Jeyaratnam
Publikováno v:
Journal of Cystic Fibrosis. 20:e63-e66
Substantial progress has been made in the treatment of Cystic fibrosis due to introduction of CFTR modulators. However, little is known about the long term side effects of treatment with these drugs. We here present a 7 year old girl with CF who pres
Autor:
Vernon K. Sondak, Andrew Poklepovic, Nikhil I. Khushalani, Jason J. Luke, Sunil Babu, Sigrun Hallmeyer, Zeynep Eroglu, Mario R. Velasco, Emily F. Higgs, Bruce Brockstein, Daniel J Olson, Thomas Krausz, Madhuri Bajaj, Timothy Carll, Riyue Bao, Jose Lutzky, Theodore Karrison, Brian W. Labadie, Thomas F. Gajewski, Yuanyuan Zha
Publikováno v:
J Clin Oncol
PURPOSE Combination of antiprogrammed cell death protein-1 (PD-1) plus anti–cytotoxic T-cell lymphocyte-4 (anti-CTLA-4) immunotherapy shows greater response rates (RRs) than anti-PD-1 antibody alone in melanoma, but RR after initial anti-PD-1 and p
Autor:
Yuri Gorelik, Sigal Pressman, S Greenfeld, Nathan Lederman, Chagit Friss, Naama Geva-Zatorsky, Yechezkel Kashi, Yehuda Chowers, Alexandera Blatt, Revital Kariv, Shay Freilich, G Focht, Shiran Gerassy-Vainberg, Yiska Loewenberg Weisband, Shai S. Shen-Orr, Iris Dotan
Publikováno v:
Gut
ObjectiveAnti-drug antibodies (ADA) to anti-tumour necrosis factor (anti-TNF) therapy drive treatment loss of response. An association between intestinal microbial composition and response to anti-TNF therapy was noted. We therefore aimed to assess t
Autor:
Thomas Christian Bonne, Tomas Ganz, Grace Jung, Andreas Breenfeldt Andersen, Elizabeta Nemeth, Nikolai Baastrup Nordsborg, Jesús R. Huertas, Jacob Bejder, Niels Vidiendal Olsen
Publikováno v:
Breenfeldt Andersen, A, Bonne, T C, Bejder, J, Jung, G, Ganz, T, Nemeth, E, Olsen, N V, Rodriguez Huertas, J & Nordsborg, N B 2021, ' Effects of altitude and recombinant human erythropoietin on iron metabolism: a randomized controlled trial ', American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol. 321, no. 2, pp. R152-R161 . https://doi.org/10.1152/ajpregu.00070.2021
Am J Physiol Regul Integr Comp Physiol
Am J Physiol Regul Integr Comp Physiol
Current markers of iron deficiency (ID) such as ferritin and hemoglobin have shortcomings, and hepcidin and erythroferrone (ERFE) could be of clinical relevance in relation to early assessment of ID. Here, we evaluate whether exposure to altitude-ind
Autor:
Naomi W. Lucchi, Daniel Ngamije, Eldin Talundzic, Noella Umulisa, Aline Uwimana, Ananias A. Escalante, Venkatachalam Udhayakumar, Leah F. Moriarty, Anicet Rucogoza, Ryan Sandford, Clarisse Musanabaganwa, Leon Mutesa, Rafiki M. Habimana, William R. Brieger, Aimable Mbituyumuremyi, M. Andreína Pacheco, Ira F. Goldman, Tharcisse Munyaneza, Samaly S. Svigel, Bryan Ezema, Michee Kabera, Kaendi Munguti, Eric S. Halsey, Zhiyong Zhou, Emily Piercefield, Monique Murindahabi, Meera Venkatesan, Jean Louis N. Mangala
Publikováno v:
The Lancet Infectious Diseases. 21:1120-1128
Summary Background Partial artemisinin resistance is suspected if delayed parasite clearance (ie, persistence of parasitaemia on day 3 after treatment initiation) is observed. Validated markers of artemisinin partial resistance in southeast Asia, Pla
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 16:393-406
Background: ATP-Binding Cassette subfamily G member 2 (ABCG2) is a semi-transport protein that plays a key role in human diseases, including bladder cancer and lung cancer, and maybe resistant to chemotherapy drugs. Objective: The present study aimed
Autor:
Ryoichi Hamasuna, Yoshiki Hiyama, Yasutomo Nasu, Teruhiko Yokoyama, Naoya Masumori, Yasuharu Kunishima, Kanao Kobayashi, Hiroyuki Kitano, Katsumi Shigemura, Takuhisa Nukaya, Hiroki Yamada, Koichiro Wada, Shin Ito, Masanobu Tanimura, Satoshi Uno, Satoshi Takahashi, Herik Acosta, Jun Teishima, Takuya Sadahira, Shingo Yamamoto, Yoshikazu Togo, Hiroshi Kiyota, Mitsuru Yasuda, Hiroshi Hayami, Soichi Arakawa, Tohru Nakagawa, Toyohiko Watanabe, Motoo Araki, Hirochika Nakajima, Jun Miyazaki, Shinya Uehara, Masato Fujisawa, Kiyohito Ishikawa, Yuki Maruyama
Publikováno v:
Journal of Infection and Chemotherapy. 27:1169-1180
Introduction The aim of this study was to monitor the development of drug-resistant bacteria isolated from acute uncomplicated cystitis (AUC) and to evaluate methodology of the survey conducted by collecting only clinical data. Methods We enrolled fe
Publikováno v:
British Journal of Cancer
Background Cancer stem cells (CSCs) are related to the patient’s prognosis, recurrence and therapy resistance in oesophageal squamous cell carcinoma (ESCC). Although increasing evidence suggests that aspirin (acetylsalicylic acid, ASA) could lower