Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pan Deng"'
Autor:
Jacqueline R. Leachman, Taylor Valentino, Michael D. Flythe, Hunter N. B. Moseley, Andrew J. Morris, Pan Deng, Bernhard Hennig
Publikováno v:
J Proteome Res
The gut microbiome generates numerous metabolites that exert local effects and enter the circulation to affect the functions of many organs. Despite extensive sequencing-based characterization of the gut microbiome, there remains a lack of understand
Autor:
Jessie B. Hoffman, Bernhard Hennig, Maria P. Kraemer, Andrew J. Morris, Pan Deng, Xu-Sheng Li, Chunyan Wang, Michael C. Petriello
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 1, Pp 45-53 (2020)
J Lipid Res
J Lipid Res
Elevated circulating levels of ceramides (Cers) are associated with increased risk of cardiometabolic diseases, and Cers may play a causative role in metabolic dysfunction that precedes cardiac events, such as mortality as a result of coronary artery
Publikováno v:
Pesticide Biochemistry and Physiology. 160:30-39
An exploration of novel control strategies for Leptinotarsa decemlineata is becoming more pressing given rapid evolution of insecticide resistance and rise of production loss of potato. Dietary delivery of bacterially expressed double-stranded RNA (d
Autor:
Xuqi Chen, Patrick Tso, Ryan E. Temel, Sean E. Thatcher, Pan Deng, Michael C. Petriello, Xuping Wang, Wendy S. Katz, Yasir Alsiraj, Heba Ali, Eric M. Blalock, Lisa A. Cassis, Katherine L. Thompson, Aldons J. Lusis, Karen Reue, Andrew J. Morris, Arthur P. Arnold, Lei Cai
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
Men and women differ in circulating lipids and coronary artery disease (CAD). While sex hormones such as estrogens decrease CAD risk, hormone replacement therapy increases risk. Biological sex is determined by sex hormones and chromosomes, but effect
Functional characterization of ultraspiracle inLeptinotarsa decemlineatausing RNA interference assay
Publikováno v:
Insect Molecular Biology. 28:676-688
A heterodimer of ultraspiracle (USP) and ecdysone receptor (EcR) mediates 20-hydroxyecdysone (20E) signalling cascade to regulate insect moulting and metamorphosis. However, at least two questions remain to be addressed in terms of the molecular impo
Publikováno v:
Insect Science
A heterodimer of two nuclear receptors, ecdysone receptor (EcR) and ultraspiracle, mediates 20‐hydroxyecdysone (20E) signaling to modulate many aspects in insect life, such as molting and metamorphosis, reproduction, diapause and innate immunity. I
Publikováno v:
Insect Molecular Biology. 28:420-430
Broad-Complex (BrC) is a downstream target of both 20-hydroxyecdysone and juvenile hormone signalling. BrC regulates morphogenetic changes between nymphal instars in hemimetabolans, whereas it controls pupal commitment, pupal morphogenesis and inhibi
Autor:
Pan Deng, Yanan Cao, B. Mark Evers, Andrew J. Morris, Side Liu, Qing Ye, Chi Wang, Zhaohe Zhou, Yekaterina Y. Zaytseva, Qing-Bai She, Eun Y. Lee, Yubin Guo, Daheng He, Charles E. Schwartz
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Dysregulation of polyamine metabolism has been linked to the development of colorectal cancer (CRC), but the underlying mechanism is incompletely characterized. Here, we report that spermine synthase (SMS), a polyamine biosynthetic enzyme, is overexp
Publikováno v:
Insect Biochemistry and Molecular Biology. 97:1-9
In the tobacco hornworm Manduca sexta, juvenile hormone (JH) is critical for the control of species-specific size. However, whether the basic helix-loop-helix/Per-Arnt-Sim domain receptor methoprene-tolerant (Met) is involved remains unconfirmed. In
Autor:
Pan Deng, Cole M. Haynes
Publikováno v:
Seminars in Cancer Biology. 47:43-49
Mitochondria form a cellular network of organelles, or cellular compartments, that efficiently couple nutrients to energy production in the form of ATP. As cancer cells rely heavily on glycolysis, historically mitochondria and the cellular pathways i