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Autor:
Isamu Okamoto, Tatsuo Ohira, Nobuyuki Yamamoto, Hidehito Horinouchi, Toyoaki Hida, Shinji Atagi, Tatsuro Fukuhara, Miyako Satouchi, Kazuma Kishi, Shunichi Sugawara, Shi Rong Han, Hideo Saka, Victoria Ebiana, Katsuyuki Hotta, Keisuke Aoe, Kazuhiko Nakagawa, Hiroshi Sakai, Hiroaki Okamoto, Kazuo Noguchi, Kaname Nosaki, Atsushi Horiike, Shigeki Umemura, Toshiaki Takahashi, Takayasu Kurata, Nobuyuki Katakami, Akimasa Sekine
Publikováno v:
Cancer Science
Cancer Sci
Cancer Sci
This prespecified subanalysis of the global, randomized controlled phase III KEYNOTE‐024 study of pembrolizumab vs chemotherapy in previously untreated metastatic non‐small‐cell lung cancer without EGFR/ALK alterations and a programmed death li
Autor:
Yohei Masugi, Hirokazu Matsushita, Hiroaki Kuroda, Yusuke Takahashi, Takao Shigenobu, Ryutaro Hanawa, Atsushi Tajima
Publikováno v:
Clinical Lung Cancer. 22:e820-e828
Histologic subtyping offers some prognostic value in lung adenocarcinoma. We thus hypothesized that histologic subtypes may be useful for risk stratification of brain metastasis (BM). In this study, we aimed to investigate the impact of histologic su
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Radiation-induced lymphopenia is associated with worse outcomes in solid tumors. We assessed the impact of interleukin-7 (IL-7), a key cytokine in lymphocyte homeostasis, on radiation-induced lymphopenia.Materials and Methods A post-hoc analy
Autor:
Clémence Breton, Jean-Baptiste Bachet, Jaafar Bennouna, Sylvain Manfredi, Jean-Louis Legoux, Aimery de Gramont, Karine Le Malicot, Thomas Aparicio, Thierry Lecomte, Olivier Bouché, Michel Ducreux, Olayidé Boussari, Julien Taieb, Jean-Marc Gornet
Publikováno v:
European Journal of Cancer. 153:40-50
Few studies have explored the association between baseline characteristics and the occurrence of early toxicities in patients treated with first-line chemotherapy for metastatic colorectal cancer (mCRC).Individual patient data of 2190 patients enroll
Autor:
Daniel Ansari, Katarzyna Said Hilmersson, Bodil Andersson, Johannes Byrling, Roland Andersson
Publikováno v:
Clinical & Translational Oncology
Purpose Distal cholangiocarcinoma and pancreatic ductal adenocarcinoma are malignancies with poor prognoses that can be difficult to distinguish preoperatively. Thrombospondin-2 has been proposed as a novel diagnostic biomarker for early pancreatic d
Publikováno v:
Cancer Investigation. 39:597-606
Fourty-five breast cancer patients and 50 apparently healthy sex-matched controls from the University of Ilorin Teaching Hospital were enrolled in this study. Plasma D-dimer and fibrinogen were found to be significantly higher than controls; APTT was
Publikováno v:
Cancer Medicine, Vol 10, Iss 14, Pp 4844-4854 (2021)
Cancer Medicine
Cancer Medicine
Background The purpose of the study was to evaluate the diagnostic value of gamma‐glutamyl transpeptidase to alkaline phosphatase ratio (GAPR) combined with gamma‐glutamyl transpeptidase to aspartate aminotransferase ratio (GAR) and alanine amino
Autor:
Nelly Firmin, C. Touraine, Véronique D'Hondt, L. Roca, S Pouderoux, Hélène de Forges, Lobna Rifai, Séverine Guiu, Marie Viala, William Jacot, Gilles Romieu, Manon Metge
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Cancer
BMC Cancer, BioMed Central, 2021, 21 (1), pp.815. ⟨10.1186/s12885-021-08563-4⟩
BMC Cancer
BMC Cancer, BioMed Central, 2021, 21 (1), pp.815. ⟨10.1186/s12885-021-08563-4⟩
Background Changes in calcium metabolism and calcium urinary excretion during chemotherapy have not been thoroughly assessed in patients with early breast cancer (EBC), a population who frequently present vitamin D insufficiency. As hypercalciuria is
Autor:
Peter O’Brien, John F. Seymour, Richard W. Tsang, Anne Capp, Michael MacManus, Mathias Bressel, Andrew Wirth, Stephen Lade, Daniel Roos
Publikováno v:
European Journal of Cancer. 152:129-138
Background This Phase 2 multicentre trial in localised non-gastric marginal zone lymphoma (MZL) evaluated the effectiveness and safety of radiotherapy and documented markers of autoimmunity and Helicobacter pylori infection. Patients and methods Elig
Autor:
Pieter J. Tanis, Marloes A. G. Elferink, Johannes H. W. de Wilt, Cornelis Verhoef, Jan M. van Rees, Jacobus W. A. Burger
Publikováno v:
European Journal of Cancer, 152, 183-192
European Journal of Cancer, 152, 183-192. Elsevier Limited
European Journal of Cancer, 152, pp. 183-192
European journal of cancer (Oxford, England : 1990), 152, 183-192. Elsevier Ltd.
European Journal of Cancer, 152, 183-192. Elsevier Limited
European Journal of Cancer, 152, pp. 183-192
European journal of cancer (Oxford, England : 1990), 152, 183-192. Elsevier Ltd.
Aim: To describe the incidence, treatment and survival of patients with rare types of rectal malignancies in the Netherlands. Methods: Data of patients with rectal malignancies diagnosed in the Netherlands between 1989 and 2018 were retrieved from th