Zobrazeno 1 - 10
of 81
pro vyhledávání: '"ZHAO LI"'
Autor:
Wen-Qiong Xue, Xiao-Hui Zheng, Xi-Zhao Li, Yijun Zhang, Jiang-Bo Zhang, Xia-Ting Tong, Zi-Yi Wu, Lian-Jing Cao, Dong Chen, Wei Hua Jia, Si-Qi Dong
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-16 (2021)
Journal of Experimental & Clinical Cancer Research : CR
Journal of Experimental & Clinical Cancer Research : CR
Background Distant metastasis is the leading cause of death for esophageal squamous cell carcinoma (ESCC) with limited treatment options and unsatisfactory effectiveness. Bromodomain (BRD) containing proteins are emerging targets for cancer therapy w
Publikováno v:
Transl Lung Cancer Res
BACKGROUND: The development of metastasis is the primary cause of death in patients with non-small cell lung cancer (NSCLC). However, identifying those NSCLC patients who will have loco-regional or distant disease recurrence after surgery is still ch
Autor:
Ze Tao, Tianshan She, Yanru Feng, Shisheng Wang, Heng Li, Xiaofeng Lu, Yan Liang, Zhao Li, Jingqiu Cheng, Hao Yang, Jie Chen, Qiuxiao Shi
Publikováno v:
Theranostics
Chemotherapeutic multidrug resistance (MDR) is the major hindrance for clinical therapy of colorectal cancer (CRC). Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) with selective cytotoxicity might overcome MDR of CRC cells. Unfortuna
Autor:
Aie Xu, Yangyang Ma, Mengyan Zhu, Jiaqi Wang, Wenzhong Yu, Yongping Xu, Xiaoyan Zhang, Ping Wang, Yong Li, Zhao Li
Publikováno v:
Journal of Investigative Dermatology. 141:374-384
Ubiquitin-conjugating enzyme E2S (UBE2S) is involved in protein degradation and signal transduction, but its function in the development of melanoma is unclear. We focused on the role of UBE2S in melanoma development both in vitro and in vivo. UBE2S
Publikováno v:
Journal of Cancer
Background: Tissue inhibitor of metalloproteinases (TIMP) gene family, including TIMP1, TIMP2, TIMP3 and TIMP4, was found to be correlated with serval cancers. Still the diagnostic and prognostic study of it in gastric cancer (GC) have few reports. M
Autor:
Si-Qi Dong, Lian-Jing Cao, Tong-Min Wang, Pei-Fen Zhang, Wen-Qiong Xue, Jing-Wen Huang, Yong-Qiao He, Zi-Yi Wu, Xiao-Hui Zheng, Xi-Zhao Li, Wei Hua Jia, Da-Wei Yang, Jiang-Bo Zhang
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Capecitabine is an extensively used oral prodrug of 5-fluorouracil in treatment of colon cancer and is known to cause hand-foot syndrome (HFS). As the target enzyme for capecitabine, thymidylate synthase (TYMS) plays a key role for 5-fluorour
Autor:
Zhao Li, Wen-Jun Duan, Hai-Zhi Liu, Xiao-Xiao Li, Yu-Lin Guo, Dan-Hua Lu, Rong-Rong He, Xiao-Hui Ma, Yi-Fang Li, Hiroshi Kurihara, Wei Bi
Publikováno v:
Acta Pharmacol Sin
GM1 ganglioside is particularly abundant in the mammalian central nervous system and has shown beneficial effects on neurodegenerative diseases. In this study, we investigated the therapeutic effect of GM1 ganglioside in experimental models of Parkin
Autor:
Jiang-Bo Zhang, Yong-Qiao He, Wen-Qiong Xue, Wei Hua Jia, Ming-Yuan Chen, Xiao-Hui Zheng, Shen Guoping, Shao-Dan Zhang, Ye-Zhu Hu, Tong-Min Wang, Ruo-Wen Xiao, Ying Sun, Xi-Zhao Li, Da-Wei Yang, Pei-Fen Zhang
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-12 (2020)
Journal of Translational Medicine
Journal of Translational Medicine
Background Radiation-induced oral mucositis (OM) is one of the most common acute complications for head and neck cancer. Severe OM is associated with radiation treatment breaks, which harms successful tumor management. Radiogenomics studies have indi
Publikováno v:
Genetic Testing and Molecular Biomarkers. 24:285-295
Background: Lung cancer is the leading cause of cancer-related deaths worldwide, imposing an enormous economic burden on society. Several studies have identified a link between the genetic polymorp...
Autor:
Haifeng Zhang, Huanjiao Jenny Zhou, Wei Ming Ni, Zhao Li, Richard W. Pierce, Mingzhu Yin, Wang Min
Publikováno v:
Circ Res
Rationale: BMX (bone marrow kinase on the X chromosome) is highly expressed in the arterial endothelium from the embryonic stage to the adult stage in mice. It is also expressed in microvessels and the lymphatics in response to pathological stimuli.