Zobrazeno 1 - 10
of 5 197
pro vyhledávání: ''
Publikováno v:
BMJ Case Rep
Statin-induced necrotising autoimmune myopathy (SINAM), a rare complication of statin use, presents with significant proximal muscle weakness and raised creatine kinase (CK) levels (50–100 times). This is different from other musculoskeletal condit
Publikováno v:
BMJ Case Rep
This case report describes a young man with a history of lymphoedema and long-standing gastrointestinal symptoms since childhood. After undergoing extensive investigations, he was diagnosed with primary intestinal lymphangiectasia (IL). The patient
Publikováno v:
BMJ Case Rep
A 55-year-old male presented to our emergency department with haematuria and abdominal pain. Investigations including a computed tomography (CT) scan revealed an intraluminal filling defect within the left collecting system, consistent in appearance
Publikováno v:
Brain, Behavior, and Immunity. 97:394-409
Untreated perinatal depression can have severe consequences for the mother and her children. However, both the efficacy to mothers and safety to exposed infants of pharmacological antidepressants such as selective serotonin reuptake inhibitors (SSRIs
Publikováno v:
The Journal of Nutrition
Background Supplementation of citicoline (CDP-choline), a naturally occurring mononucleotide, has shown beneficial effects on memory function and behavior in populations with a wide range of impairments. However, few studies have investigated its eff
Autor:
Kyle J. Burghardt, Berhane Seyoum, Aktham Mestareehi, Abdullah Mallisho, Zaher Msallaty, Zhengping Yi, Anjaneyulu Kowluru, Xiangmin Zhang
Publikováno v:
Journal of Diabetes Research
Journal of Diabetes Research, Vol 2021 (2021)
Journal of Diabetes Research, Vol 2021 (2021)
Context. Skeletal muscle insulin resistance is one of the primary contributors of type 2 diabetes (T2D). Metformin is the first-line drug for the treatment of T2D. The primary effects of metformin include decreasing glucose production in the liver an
Autor:
Soha Parhiz, Navideh Sahebi Vaighan, Taraneh Moini Zanjani, Masoumeh Sabetkasaei, Malek Zarei
Publikováno v:
Scandinavian Journal of Pain. 22:186-192
Objectives To alleviate different pain intensities, morphine administration has been extensively used. However, prolonged administration of morphine leads to a progressive decline of its analgesic effect which limits their overall utility. Morphine t
Autor:
Richard M. Weinshilboum, David Goldman, Jennifer R. Geske, Victor M. Karpyak, Sofia Pozsonyiova, Colin A. Hodgkinson, Lea Zillich, Ada Man-Choi Ho, Ray Anton, Colin L. Colby, Ming Fen Ho, Brandon J. Coombes, Anthony Batzler, Stephanie S. O'Malley, Josef Frank, Joanna M. Biernacka, M. Rietschel, Karl Mann, Falk Kiefer, Michelle K. Skime
Publikováno v:
Neuropsychopharmacology
Naltrexone can aid in reducing alcohol consumption, while acamprosate supports abstinence; however, not all patients with alcohol use disorder (AUD) benefit from these treatments. Here we present the first genome-wide association study of AUD treatme
Autor:
Julia Czuprynska, László Sztriha, Biba R. Stanton, Sean Apap Mangion, Puja Mehta, Matthew Benger, Roopen Arya
Publikováno v:
Brain, Behavior, and Immunity
Recent reports have highlighted rare, and sometimes fatal, cases of cerebral venous sinus thrombosis (CVST) and thrombocytopenia following the Vaxzevria vaccine. An underlying immunological mechanism similar to that of spontaneous heparin-induced thr
Publikováno v:
Neurobiology of Aging. 103:31-41
In sporadic Alzheimer's disease (SpAD), acetylcholinesterase and butyrylcholinesterase, co-regulators of acetylcholine, are associated with β-amyloid plaques and tau neurofibrillary tangles in patterns suggesting a contribution to neurotoxicity. Thi