Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Yoshitaka Kitayama"'
Publikováno v:
Journal of Clinical Gastroenterology. 55:12-20
Interpreting natural course studies have been very difficult due to their retrospective design, lack of standardization, reliability of reported mucosal findings, liberal use of antireflux medications and accuracy of chart documentation. Studies prov
Publikováno v:
Journal of Clinical Gastroenterology. 54:485-492
Various esophageal functional abnormalities have been described in patients with Barrett's esophagus (BE). A significantly higher esophageal acid exposure especially in the supine position has been documented in BE, as compared with the other gastroe
Autor:
Yoshitaka Kitayama, Takashi Kondo, Tadayuki Oshima, Katsuyuki Tozawa, Hirotsugu Eda, Kumiko Nakamura, Takahisa Yamasaki, Toshihiko Tomita, Hirokazu Fukui, Takuya Okugawa, Akio Tamura, Hiroto Miwa, Tomoaki Kono, Tomoki Horikawa, Min Li, Jiro Watari, Tomohiro Ogawa
Publikováno v:
Digestion. 100:286-294
Background/Aims: Bile acids have recently been associated with the pathogenesis of irritable bowel syndrome (IBS). We therefore evaluated the expression of bile acid receptors in the intestinal mucosa of IBS patients as well as the effects of bile ac
Autor:
Tadayuki Oshima, Jiro Watari, Hiroto Miwa, Hirokazu Fukui, Mo Yang, Ken Hara, Hirotsugu Eda, Yoshitaka Kitayama, Mio Kodani, Xin Xu, Toshihiko Tomita
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 312:G367-G373
The microbiota in the gut is known to play a pivotal role in host physiology by interacting with the immune and neuroendocrine systems in gastrointestinal (GI) tissues. Glucagon-like peptide 1 (GLP-1), a gut hormone, is involved in metabolism as well
Autor:
Jiro Watari, Hirotsugu Eda, Mo Yang, Shin Takasawa, Mio Kodani, Chao Sun, Yoshitaka Kitayama, Toshihiko Tomita, Hirokazu Fukui, Hiroto Miwa, Ken Hara, Tadayuki Oshima, Hidetsugu Yamagishi
Publikováno v:
Translational Research. 173:92-100
We have recently shown that loss of the regenerating gene (Reg) I causes susceptibility to nonsteroidal anti-inflammatory drug–induced gastrointestinal damage. However, the mechanism by which Reg I plays a protective role against this pathophysiolo
Autor:
Mio Kodani, Tadayuki Oshima, Jiro Watari, Toshihiko Tomita, Hirotsugu Eda, Hirokazu Fukui, Mo Yang, Ryosuke Uchiyama, Ken Hara, Hiroko Tsutsui, Hiroto Miwa, Yoshitaka Kitayama
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0177232 (2017)
PLoS ONE
PLoS ONE
Background Although Helicobacter pylori (H. pylori) infection is closely associated with the development of peptic ulcer, its involvement in pathophysiology in the lower intestinal tract and gastrointestinal (GI) motility remains unclear. Glucagon-li
Autor:
Mo Yang, Hirotsugu Eda, Tadayuki Oshima, Yoshitaka Kitayama, Ken Hara, Hirokazu Fukui, Hiroto Miwa, Toshihiko Tomita, Jiro Watari, Mio Kodani
Publikováno v:
Molecular medicine reports. 16(3)
Serotonin (5‑hydroxytryptamine; 5‑HT) may be a key player in gastrointestinal (GI) motility and the GI immune system. In the present study, the effect of gut microbiota on the association between GI motility, and 5‑HT expression and macrophage