Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Vasileios Stathias"'
Publikováno v:
Semin Cancer Biol
Knowledge of the underpinnings of cancer initiation, progression and metastasis has increased exponentially in recent years. Advanced "omics" coupled with machine learning and artificial intelligence (deep learning) methods have helped elucidate targ
Autor:
Raymond Terryn, Alexander Lachmann, Vasileios Stathias, John Paul Turner, Afoma C. Umeano, Daniel J.B. Clarke, Dusica Vidovic, John Erol Evangelista, Amar Koleti, Marcin Pilarczyk, Stephan C. Schürer, Mehdi Fazel-Najafabadi, Caty Chung, Daniel J. Cooper, Avi Ma'ayan, Mario Medvedovic
Publikováno v:
Nucleic Acids Research
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program with the goal of generating a large-scale and comprehensive catalogue of perturbation-response signatures by utilizing a diverse collection of perturbat
Autor:
Cristina E. Tognon, Larisa Polonskaya, Tara Skelly, Shuang Cai, Francesmary Modugno, Larissa Rossell, Nancy Roche, Chen Huang, Jessika Baral, Fulvio D'Angelo, Wen-Wei Liang, Chia-Feng Tsai, Sneha P. Couvillion, Karin D. Rodland, Jun Zhu, Liang-Bo Wang, Paul D. Piehowski, Antonio Colaprico, Anupriya Agarwal, Matthew A. Wyczalkowski, Umut Ozbek, Francesca Petralia, Alexis Demopoulos, William W. Maggio, Lin Chen, Katherine A. Hoadley, Richard D. Smith, Sandra Cottingham, John McGee, Marcin J. Domagalski, Houxiang Zhu, Emek Demir, Rebecca I. Montgomery, Jamie Moon, Rashna Madan, George D. Wilson, Luciano Garofano, Ewa P. Malc, Chelsea J. Newton, Steven A. Carr, Chandan Kumar-Sinha, Donghui Tan, Christopher R. Kinsinger, Oxana Paklina, Weiqing Wan, Stephanie De Young, Sandra Cerda, Shankha Satpathy, Wojciech Kaspera, Linda Hannick, Gad Getz, Runyu Hong, Shuangjia Lu, Ziad Hanhan, Daniel C. Rohrer, Annette Marrero-Oliveras, Wojciech Szopa, Yuxing Liao, Amanda G. Paulovich, Jiayi Ji, Denis A. Golbin, Tara Hiltke, Weiva Sieh, Piotr A. Mieczkowski, Matthew E. Monroe, Gilbert S. Omenn, Jill S. Barnholtz-Sloan, Azra Krek, Bing Zhang, Brittany Henderson, Peter B. McGarvey, Ratna R. Thangudu, Maciej Wiznerowicz, Saravana M. Dhanasekaran, Alex Webster, Kai Li, Karna Robinson, Nan Ji, Karl K. Weitz, Simina M. Boca, Xiaoyu Song, Anna Calinawan, Adam C. Resnick, Brian J. Druker, Dana R. Valley, David J. Clark, Tao Liu, Eric J. Jaehnig, Alicia Francis, Michele Ceccarelli, Rui Zhao, Dmitry Rykunov, Boris Reva, Elizabeth R. Duffy, Antonio Iavarone, Dave Tabor, Joshua F. McMichael, Daniel Cui Zhou, Maureen Dyer, Kimberly Elburn, Scott D. Jewell, Negin Vatanian, Shirley Tsang, Seungyeul Yoo, Alexander R. Pico, Grace Zhao, Kent J. Bloodsworth, Chet Birger, Jena Lilly, Eunkyung An, Jeffrey R. Whiteaker, Albert H. Kim, Yige Wu, Karen A. Ketchum, Felipe D. Leprevost, Alcida Karz, Uma Borate, Nathan Edwards, Uma Velvulou, Melissa Borucki, Vasileios Stathias, Sanford P. Markey, Corbin D. Jones, Ronald J. Moore, MacIntosh Cornwell, Karsten Krug, Michael J. Birrer, James Suh, Tomasz Czernicki, Jason E. McDermott, Emily S. Boja, Pei Wang, Nina Martinez, Wenke Liu, Yan Shi, Lili Blumenberg, Emily Kawaler, Jeffrey W. Tyner, Feng Chen, Jakub Stawicki, Ki Sung Um, Arul M. Chinnaiyan, Robert Zelt, Jacob J. Day, Zhen Zhang, Caleb M. Lindgren, Li Ding, Nikolay Gabrovski, Hongwei Liu, Jonathan T. Lei, Alla Karpova, Ramani B. Kothadia, Sailaja Mareedu, Mitual Amin, Hannah Boekweg, Jennifer E. Kyle, Sara R. Savage, Brian R. Rood, Yuriy Zakhartsev, Matthew L. Anderson, Alyssa Charamut, Wagma Caravan, Shakti Ramkissoon, Junmei Wang, Song Cao, Samuel H. Payne, Rosalie K. Chu, Rajiv Dhir, David W. Andrews, Galen Hostetter, Liqun Qi, Zhiao Shi, Milan G. Chheda, Robert Edwards, Hui Zhang, Weiping Ma, Jennifer M. Eschbacher, Stacey Gabriel, Jan Lubinski, Lijun Yao, Erika M. Zink, Kelly L. Stratton, William Bocik, Mathangi Thiagarajan, Shilpi Singh, Michael A. Gillette, Lisa M. Bramer, Thomas L. Bauer, Michael Vernon, Henry Rodriguez, Dimitris G. Placantonakis, Eric E. Schadt, Alexey I. Nesvizhskii, Vladislav A. Petyuk, Ana I. Robles, Yvonne Shutack, Anna Malovannaya, Stephen E. Stein, Xi Chen, Lyndon Kim, Yize Li, Shannon Richey, Stephan C. Schürer, Barbara Hindenach, Matthew J. Ellis, Yongchao Dou, David Fenyö, Amy M. Perou, Olga Potapova, Shrabanti Chowdhury, Andrew K. Godwin, Marcin Cieślik, Michael C. Wendl, Marina A. Gritsenko, Pietro Pugliese, Elie Traer, Simona Migliozzi, D. R. Mani, Houston Culpepper, Gregory J. Riggins, Xiaolu Yang, Mehdi Mesri, David Chesla, Lindsey K. Olsen, Lori J. Sokoll, Suhas Vasaikar, Liwei Zhang, Meghan C. Burke, Kelly V. Ruggles, Qing Kay Li, Daniel W. Chan, Bo Wen, Nicollette Maunganidze, Darlene Tansil, Joseph H. Rothstein, Barbara Pruetz, Pushpa Hariharan
Publikováno v:
Cancer Cell
Glioblastoma (GBM) is the most aggressive nervous system cancer. Understanding its molecular pathogenesis is crucial to improving diagnosis and treatment. Integrated analysis of genomic, proteomic, post-translational modification and metabolomic data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df38d0a8bf9434909b50050c641f50e
http://hdl.handle.net/11588/844575
http://hdl.handle.net/11588/844575
Autor:
Nicholas A. Clark, Marc R. Birtwistle, Jennifer E. Van Eyk, Moshe C. Silverstein, Caitlin E. Mills, Mario Niepel, Marcin Pilarczyk, Alexander Lachmann, Elizabeth H. Williams, Simon Koplev, Nathanael S. Gray, Uzma Hussain, Albert Lee, Ajay Pillai, Edward He, Mark A. Dane, Evren U. Azeloglu, Dusica Vidovic, Jeannette Osterloh, Maria G. Banuelos, Maxim V. Kuleshov, Rick J. Koch, Stephan C. Schürer, Karen Sachs, Damir Sudar, Divya Ramamoorthy, Dhruv Sareen, Shana White, Heidi S. Feiler, Siva Sivaganesan, Kathleen M. Jagodnik, Clive N. Svendsen, Mohammad Fallahi-Sichani, Miriam Adam, Jaroslaw Meller, Todd R. Golub, Ravi Iyengar, Jennifer Stocksdale, Amar Koleti, David Wrobel, Sherry L. Jenkins, Jacob D. Jaffe, Alexandra B Keenan, Renan Escalante-Chong, Daniel J. Cooper, Loren Ornelas, Joe W. Gray, Alexander LeNail, Ritchie Ho, Alyssa Coye, Avi Ma'ayan, Steve Finkbiener, Lixia Zhang, Andrea Matlock, Eric A. Sobie, Vidya Venkatraman, Anders B. Dohlman, Jeffrey D. Rothstein, Michele Forlin, Jonathan Z. Li, Rebecca Smith, Naim Al Mahi, Kaylyn Devlin, Caty Chung, Marc Hafner, Malvina Papanastasiou, Wen Niu, Michal Kouril, Ryan G. Lim, Yan Ren, Julia A. Kaye, Malcolm Casale, Jie Wu, Mario Medvedovic, Jeremy L. Muhlich, Victoria Dardov, Jouzas Vasiliauskas, Kelly Haston, Caroline E. Shamu, Raymond Terryn, John F. Reichard, Michel Nederlof, David Kilburn, Leslie M. Thompson, Jia-Ren Lin, Vasileios Stathias, Zichen Wang, Behrouz Shamsaei, James E. Korkola, Pamela Milani, Berhan Mandefro, Terri G. Thompson, Laura M. Heiser, Gavin Daigle, Denis Torre, Ron Margolis, Aravind Subramanian, Elmar Bucher, Sean D. Erickson, Ernest Fraenkel, Jaslin Kalra, Mark A. LaBarge, Gordon B. Mills, Peter K. Sorger, Sean M. Gross, Leslie Derr, Mehdi Fazel
Publikováno v:
Cell Systems. 6:13-24
The Library of Integrated Network-Based Cellular Signatures (LINCS) is an NIH Common Fund program that catalogs how human cells globally respond to chemical, genetic, and disease perturbations. Resources generated by LINCS include experimental and co
Autor:
Caty Chung, Nicholas A. Clark, Michele Forlin, John Paul Turner, Christopher C. Mader, Mehdi Fazel, Sherry L. Jenkins, Amar Koleti, Naim Al Mahi, John F. Reichard, Tanya T. Kelley, Alessandro D'Urso, Kathleen M. Jagodnik, Dusica Vidovic, Mario Medvedovic, Marcin Pilarczyk, Vasileios Stathias, Behrouz Shamsaei, Lily Wang, Wen Niu, Avi Ma'ayan, Stephan C. Schürer, Daniel J. Cooper, Denis Torre, Bryce K. Allen, Raymond Terryn, Juozas Vasiliauskas, Jarek Meller, Ajay Pillai
Publikováno v:
Nucleic Acids Research
The Library of Integrated Network-based Cellular Signatures (LINCS) program is a national consortium funded by the NIH to generate a diverse and extensive reference library of cell-based perturbation-response signatures, along with novel data analyti
Publikováno v:
SSRN Electronic Journal.
The approval of the first kinase inhibitor, Gleevec, in 2001, ushered in a paradigm shift for oncological treatment—the use of genomic data for targeted, efficacious therapies. Since then, over 48 additional small molecule kinase inhibitors have be
Autor:
Jezabel Rodriguez-Blanco, Cheng Ming Chiang, Sze Kiat Tan, Jae K. Lee, Vasileios Stathias, Camilo Valdes, Jennifer Clarke, Mary E. Hatten, Daniel J. Liebl, David J. Robbins, Jun Long, Jose Mier, Yin Fang, Marie E. Maloof, Clara Penas, Nagi G. Ayad
Publikováno v:
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Universitat Autònoma de Barcelona
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Cerebellar neuronal progenitors undergo a series of divisions before irreversibly exiting the cell cycle and differentiating into neurons. Dysfunction of this process underlies many neurological diseases including ataxia and the most common pediatric
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22223feb68086a58d8088ae86b5b3faf
https://ddd.uab.cat/record/223913
https://ddd.uab.cat/record/223913
Autor:
Robert Suter, Vasileios Stathias, Claude-Henry Volmar, Ricardo J. Komotar, Winston M. Walters, Marie E. Maloof, Regina M. Graham, Stephan C. Schürer, Michael A. Durante, Anna Jermakowicz, Nicholas J. Lyons, Sion L. Williams, Michele Forlin, Aravind Subramanian, Todd R. Golub, Nagi G. Ayad, Claes Wahlestedt, J. William Harbour, Jann N. Sarkaria, Michael E. Ivan
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Glioblastoma (GBM) is the most common primary adult brain tumor. Despite extensive efforts, the median survival for GBM patients is approximately 14 months. GBM therapy could benefit greatly from patient-specific targeted therapies that maximize trea
Autor:
Daniel G. Tenen, Stephen D. Nimer, Samantha Newman, Feng Chun Yang, Ye Xu, Fan Liu, Stephanie Duffort, Ryan G. Kruger, Ly P. Vu, Concepción Martínez, Stephan C. Schürer, Daniel Bilbao, Sarah Greenblatt, Takashi Asai, Ezra Blumenthal, Pierre-Jacques Hamard, Mingjiang Xu, Vasileios Stathias, Madhavi Tadi, Na Man, Francisco Vega, Daniel L. Karl, Justin M. Watts, Anna Jermakowicz, Michael T. McCabe
Publikováno v:
Cancer cell. 34(5)
Summary Chromatin-modifying enzymes, and specifically the protein arginine methyltransferases (PRMTs), have emerged as important targets in cancer. Here, we investigated the role of CARM1 in normal and malignant hematopoiesis. Using conditional knock
Autor:
Stephan C. Schürer, Tudor I. Oprea, Oleg Ursu, Stephen L. Mathias, Cristian Bologa, Dac-Trung Nguyen, Jayme Holmes, Vasileios Stathias, Jeremy J. Yang
Publikováno v:
Nucleic Acids Research
DrugCentral is a drug information resource (http://drugcentral.org) open to the public since 2016 and previously described in the 2017 Nucleic Acids Research Database issue. Since the 2016 release, 103 new approved drugs were updated. The following n