Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Toshiro Sato"'
Autor:
Kazuhiro Togasaki, Yuki Ohta, Masayuki Fujii, Shinya Sugimoto, Mami Matano, Kosaku Nanki, Toshiro Sato, Sirirat Takahashi, Takanori Kanai
Publikováno v:
Gastroenterology. 160:823-830
Background and Aims Diffuse-type gastric cancer (GC) is currently subdivided into signet-ring cell carcinoma (SRCC) and non-SRCC, referred to as poorly cohesive carcinoma not otherwise specified (PCC-NOS). Although these subtypes are considered to be
Autor:
Ryuichi Okamoto, Toshiaki Ohteki, Takumi Akashi, Keisuke Kitagaki, Taku Sato, Hirona Yamamoto, Shun Ishikawa, Jumpei Asano, Masayuki Fujii, Kouhei Yamamoto, Toshiro Sato
Publikováno v:
Nature Cell Biology. 22:919-926
Intestinal stem cells (ISCs) are located at the crypt base and fine-tune the balance of their self-renewal and differentiation1,2, but the physiological mechanism involved in regulating that balance remains unknown. Here we describe a transcriptional
Autor:
Kohta Toshimitsu, Sirirat Takahashi, Mariko Shimokawa, Shoichi Date, Kosaku Nanki, Mami Matano, Kenta Kawasaki, Yoko Nagai, Takanori Kanai, Shingo Nishikori, Toshifumi Hibi, Soichiro Ishihara, Nobuo Sasaki, Toshiro Sato, Kosuke Yoshida, Kazuhiro Ishimaru, Ai Takano, Shinya Sugimoto, Ryota Ishii, Yuki Ohta, Masayuki Fujii
Publikováno v:
Nature. 577:254-259
With ageing, normal human tissues experience an expansion of somatic clones that carry cancer mutations1-7. However, whether such clonal expansion exists in the non-neoplastic intestine remains unknown. Here, using whole-exome sequencing data from 76
The COVID-19 pandemic has infected millions of people worldwide and many countries have been suffering from a large number of deaths. Acknowledging the ability of SARS-CoV-2 to mutate into distinct strains as an RNA virus and investigating its potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28e40a4e8ccfd8091e6ee4c003fabdec
https://doi.org/10.1101/2021.03.22.21254081
https://doi.org/10.1101/2021.03.22.21254081
Interleukin‐13 and its signaling pathway is associated with obesity‐related colorectal tumorigenesis
Autor:
Yuko Kitagawa, Masashi Tsuruta, Shimpei Matsui, Shinya Sugimoto, Takashi Ishida, Kohei Shigeta, Hirotoshi Hasegawa, Koji Okabayashi, Takayuki Kondo, Ryo Seishima, Masayuki Shimoda, Yoshiyuki Suzuki, Toshiro Sato
Publikováno v:
Cancer Science
The incidence of colorectal cancer (CRC) has been on the rise, which is linked to the increasing prevalence of obesity, based on global epidemiological evidence. Although chronic inflammation is implicated in tumor development, the mechanisms underly
Autor:
Yasuo Mori, Ayaka Hasegawa, Ha Nam Tran, Yosuke Funato, Daisuke Yamazaki, Toshiro Sato, Masayuki X. Mori, Hiroaki Miki
Publikováno v:
Oncogene. 38:3962-3969
CNNM4 is a Mg2+ transporter highly expressed in the colon epithelia. Its importance in regulating intracellular Mg2+ levels and cancer development has been documented, but how CNNM4 function affects the dynamic homeostasis of the epithelial tissue re
Autor:
Kentaro Miyamoto, Ryo Aoki, Yuzo Koda, Nobuhito Taniki, Takanori Kanai, Nobuhiro Nakamoto, Seiko Narushima, Po Sung Chu, Wataru Suda, Akihiro Yamaguchi, Kenya Honda, Masahira Hattori, Toshiro Sato, Akihiko Yoshimura, Toshiaki Teratani, Hiroshi Ashida, Mitsuhiro Kanamori, Nobuhiko Kamada, Koji Atarashi, Takahiro Suzuki, Michiie Sakamoto, Nobuo Sasaki
Publikováno v:
Nature Microbiology. 4:492-503
Primary sclerosing cholangitis (PSC) is a chronic inflammatory liver disease and its frequent complication with ulcerative colitis highlights the pathogenic role of epithelial barrier dysfunction. Intestinal barrier dysfunction has been implicated in
Autor:
Ayana Ieda, Toshiro Sato, Shuichi Kamo, Yuichi Takada, Takatoshi Yamashita, Kazuko Iwamoto, Tatsuya Moriyama, Nobuhiro Zaima
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 44-49 (2018)
Biochemistry and Biophysics Reports, Vol 16, Iss, Pp 44-49 (2018)
Soyasapogenol is a soyasaponin aglycone, which has been suggested to exert a more potent function than the glycoside form. In this study, the effect of soyasapogenol A and B on cultured adipocyte cell function was investigated using mouse 3T3-L1 adip
Autor:
Makoto Sonehara, Toshiro Sato, Kubo Toshiya, Miyamoto Mitsunori, Kenta Shiota, Fujishiro Yuta
Publikováno v:
IEEE Transactions on Magnetics. 54:1-5
The Faraday-effect has been used for the measurement of magnetic field induced by electric current. Actually, an optical fiber sensor using the Faraday-effect has been developed as an alternative method of the current-transformer in the substation of
Autor:
Kosaku Nanki, Kentaro Miyamoto, Keiko Ishikawa, Kazuya Arai, Mami Matano, Yuki Ohta, Eiji Kobayashi, Toshiro Sato, Masayuki Fujii, Sirirat Takahashi, Yoji Hakamata, Takanori Kanai, Kohta Toshimitsu, Shinya Sugimoto
Publikováno v:
Nature.
The small intestine is the main organ for nutrient absorption, and its extensive resection leads to malabsorption and wasting conditions referred to as short bowel syndrome (SBS). Organoid technology enables an efficient expansion of intestinal epith