Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Suidong Ouyang"'
Publikováno v:
JCI Insight. 5
IL-17A plays a critical role in the pathogenesis of steroid-resistant neutrophilic airway inflammation, which is a hallmark of severe asthma and chronic obstructive pulmonary disease (COPD). Through RNA sequencing analysis of transcriptomes of human
Autor:
Jodi L. Bubenik, Xing Chen, Donny D. Licatalosi, Kommireddy Vasu, Hui Yang, Tomasz Herjan, Xiao Li, Caini Liu, Xiaoxia Li, Katarzyna Bulek, Wen Qian, Suidong Ouyang, Jun Qin, Kewal Asosingh, Paul L. Fox, Lingzi Hong, Eric Cockman, Thomas A. Hamilton, Junjie Zhao, Mark A. Aronica, Donna M. Driscoll, Hao Zhou
Publikováno v:
Nature Immunology. 19:354-365
Mechanisms that degrade inflammatory mRNAs are well known; however, stabilizing mechanisms are poorly understood. Here, we show that Act1, an interleukin-17 (IL-17)-receptor-complex adaptor, binds and stabilizes mRNAs encoding key inflammatory protei
Autor:
Dean Sheppard, Jarod A. Zepp, Tomasz Herjan, Xiaoxia Li, Stavros Garantziotis, Alana K. Majors, Katarzyna Bulek, Suidong Ouyang, Arnaud Echard, Julie Carman, Mark A. Aronica, Xing Chen, Malgorzata Bodaszewska-Lubas, Ashok Dongre, Aparna Sundaram, Vandy I. Parron, Ji Gao, Caini Liu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), vol 202, iss 5
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2019, 202 (5), pp.1540-1548. ⟨10.4049/jimmunol.1801025⟩
Journal of Immunology, 2019, 202 (5), pp.1540-1548. ⟨10.4049/jimmunol.1801025⟩
Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2019, 202 (5), pp.1540-1548. ⟨10.4049/jimmunol.1801025⟩
Journal of Immunology, 2019, 202 (5), pp.1540-1548. ⟨10.4049/jimmunol.1801025⟩
IL-17A is a critical proinflammatory cytokine for the pathogenesis of asthma including neutrophilic pulmonary inflammation and airway hyperresponsiveness. In this study, by cell type–specific deletion of IL-17R and adaptor Act1, we demonstrated tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70315491f6a6a6377f8739dacdebded9
https://escholarship.org/uc/item/6hj7w802
https://escholarship.org/uc/item/6hj7w802
Autor:
Luke Qin, Xiaoxia Li, Jun Qin, Liang Zhu, Xing Chen, Cun Jin Zhang, Bradley N. Martin, Koichi Fukuda, Rachakonda Suguna, Caini Liu, Mark A. Aronica, Suidong Ouyang, Chunfang Gu, Chenhui Wang
Cyanidin, a key flavonoid that is present in red berries and other fruits, attenuates the development of several diseases, including asthma, diabetes, atherosclerosis, and cancer, through its anti-inflammatory effects. We investigated the molecular b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4e6dee49d3e311f33618cf212f36493
https://europepmc.org/articles/PMC5520994/
https://europepmc.org/articles/PMC5520994/
Publikováno v:
Cellular immunology. 302
Spontaneously occurring lymphomas in SJL mice have many pathological features similar to Hodgkin's lymphoma in humans. The malignant growth of the tumor cells is dependent on the support of host FoxP3(+)CD4(+) regulatory T cells (Tregs). In this stud
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e69356 (2013)
PLoS ONE
PLoS ONE
Interleukin (IL)-15 is a ubiquitously expressed cytokine that in the basal state is mainly localized intracellularly, including the nucleus. Unexpectedly, tumor necrosis factor-α (TNF) time-dependently induced nuclear export of IL-15Rα and IL15. Th