Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shuwen Lei"'
Publikováno v:
Food Control. 91:85-91
Vibrio parahaemolyticus, a worldwide pathogen, has been proved to be capable of entering into viable but nonculturable (VBNC) state and survive under stressful conditions. In this study, a method of real-time quantitative PCR coupled with propidium m
Publikováno v:
International journal of biological macromolecules. 184
Pathogens pose a severe threat to food safety and human health. The traditional methods for pathogen detection can't meet the growing diagnosis and control need. Digital PCR (dPCR) attracts a considerable attention for its ability to absolutely quant
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Frontiers in Microbiology
Frontiers in Microbiology
Vibrio parahaemolyticus is a significant seafood-borne pathogen, leading to serious acute gastrointestinal diseases worldwide. In this study, a reliable 4-plex droplet digital PCR (ddPCR) was successfully established and evaluated for the simultaneou
Autor:
Mojdeh S. Tavallaie, Juntao Wang, Sharmin Reza Chowdhury, Lei Fu, Faqin Jiang, Dan Lu, Shuwen Lei, Yixin Hu, Celine Lam, Jinxin Gu
Publikováno v:
European Journal of Medicinal Chemistry. 222:113541
A series of benzofuran piperidine derivatives were designed, synthesized and evaluated as multifunctional Aβ antiaggregant to treat Alzheimer's disease (AD). In vitro results revealed that all of them are very good Aβ antiaggregants and some of the
Autor:
Celine Lam, Mojdeh S. Tavallaie, Xinxian Deng, Juntao Wang, Shuwen Lei, Faqin Jiang, Jian Shen, Qingqing Cai, Ran Sun, Lei Fu
Publikováno v:
European Journal of Medicinal Chemistry. 208:112850
Our previous discovery of pyrazolo [1,5-a]pyrimidin-7(4H)-one scaffold-based DPP-4 inhibitors yielded two potent compounds b2 (IC50 = 79 nM) and d1 (IC50 = 49 nM) but characterized by cytotoxicity. Herein, with scaffold hopping and fragment-based dru