Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Peter K, Gregersen"'
Autor:
Jill M. Norris, Marie L. Feser, Kevin D. Deane, V. Michael Holers, Fan Yang, Michael H. Weisman, M. Kristen Demoruelle, Peter K. Gregersen, Tessa L. Crume, Ted R. Mikuls, Jane H. Buckner, Elizabeth A. Bemis, Jennifer Seifert, Kristen J. Polinski, Richard M. Keating, Michael J. Clare-Salzler, James R. O'Dell, Nichole Reisdorph
Publikováno v:
Arthritis Rheumatol
OBJECTIVE To determine the association of polyunsaturated fatty acid (PUFA)-derived lipid mediators with progression from rheumatoid arthritis (RA)-related autoimmunity to inflammatory arthritis (IA). METHODS We conducted a prospective cohort study u
Autor:
James R. O'Dell, Christopher C. Striebich, Stacey Brake, Perry M. Nicassio, Kevin D. Deane, V. Michael Holers, Jill M. Norris, Jennifer Seifert, Peter K. Gregersen, Jane H. Buckner, Elizabeth A. Bemis, Michael H. Weisman, Richard M. Keating, M. Kristen Demoruelle, Marie L. Feser, Ted R. Mikuls, Kristen J. Polinski
Publikováno v:
Arthritis Care Res (Hoboken)
OBJECTIVE The aim of this study was to determine the association of perceived stress with incident inflammatory arthritis (IA) defined as having at least 1 joint consistent with rheumatoid arthritis (RA)-like synovitis based on examination. METHODS W
Autor:
Maria Gutierrez-Arcelus, A. Helena Jonsson, Jatin Arora, Cristina Navarrete, Stephen S. Rich, Michael B. Brenner, Susan K. Hannes, Deepak A. Rao, Tõnu Esko, Jerome I. Rotter, Tiffany Amariuta, Yuriy Baglaenko, Peter K. Gregersen, Nikola Teslovich, Joerg Ermann, Soumya Raychaudhuri, Yang Luo, Kent D. Taylor
Publikováno v:
Nature genetics, vol 52, iss 3
Nature genetics
Nature Genetics
Nature genetics
Nature Genetics
Genetic studies have revealed that autoimmune susceptibility variants are over-represented in memory CD4+ T cell regulatory elements1–3. Understanding how genetic variation affects gene expression in different T cell physiological states is essenti
Autor:
V. Michael Holers, James R. O’Dell, Ashley Visser, Sonia Khatter, Kristen J. Polinski, Michael Mahler, Jill M. Norris, Ted R. Mikuls, Kevin D. Deane, Michael H. Weisman, M. Kristen Demoruelle, Heather M. Berens, Justin August, Jane H. Buckner, Richard M. Keating, Peter K. Gregersen
Publikováno v:
J Rheumatol
Objective.We investigated the association of age and anticyclic citrullinated peptide antibodies (anti-CCP) in subjects without rheumatoid arthritis (RA).Methods.Serum was tested for anti-CCP3.1 (IgG/IgA) in 678 first-degree relatives (FDR) of patien
Autor:
S. Louis Bridges, Carl D. Langefeld, Peter K. Gregersen, Hemant K. Tiwari, Ted R. Mikuls, Leah C. Kottyan, Maria I. Danila, Vincent A. Laufer, Jelai Wang, Jeffrey C. Edberg, Richard J. Reynolds, John B. Harley, Donna K. Arnett, Robert P. Kimberly, Devin Absher
Publikováno v:
Human Molecular Genetics. 28:858-874
Large meta-analyses of rheumatoid arthritis (RA) susceptibility in European (EUR) and East Asian (EAS) populations have identified >100 RA risk loci, but genome-wide studies of RA in African-Americans (AAs) are absent. To address this disparity, we p
Autor:
Patrick Concannon, Amy S. Shah, Linda S. Wicker, Suna Onengut-Gumuscu, Dana Dabelea, Chen W-M., Robert P. Kimberly, Jasmin Divers, David B. Dunger, Peter K. Gregersen, Jeffrey C. Edberg, Stephen S. Rich, Huan Yang, Santica M. Marcovina, Antony J. Cutler, S L Bridges, Marian Rewers, Carla J. Greenbaum, Flemming Pociot, Jorge R. Oksenberg, Jean M. Lawrence, Inshaw Jrj., D F Santa Cruz, Andrea K. Steck, Panagiotis Deloukas, Mark A. Atkinson, John A. Todd, Emily Farber, Crouch Djm., Jane H. Buckner, Catherine C. Robertson
Publikováno v:
Robertson, C C & Type 1 Diabetes Genetics Consortium 2021, ' Fine-mapping, trans-ancestral and genomic analyses identify causal variants, cells, genes and drug targets for type 1 diabetes ', Nature Genetics, vol. 53, no. 7, pp. 962-971 . https://doi.org/10.1101/2020.06.19.158071, https://doi.org/10.1038/s41588-021-00880-5
Nature genetics
Nature genetics
We report the largest and most ancestrally diverse genetic study of type 1 diabetes (T1D) to date (61,427 participants), yielding 152 regions associated to false discovery rate < 0.01, including 36 regions associated to genome-wide significance for t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a3f66533a4cf7a2a983554fd2421f8
https://curis.ku.dk/ws/files/284012839/2020.06.19.158071v1.full.pdf
https://curis.ku.dk/ws/files/284012839/2020.06.19.158071v1.full.pdf
Autor:
Meggan Mackay, Xinghao Wang, Richard Apps, Rishi R. Goel, Ashley Babyak, Valentina Giudice, Nathalia R Gazaniga, Betty Diamond, Ann Biehl, Martin P. Playford, Stephen R. Brooks, Katie Stagliano, Laura Vian, Peter K. Gregersen, Zerai Manna, Michael Davis, Shajia Lu, Elaine Poncio, Yinghui Shi, Nehal N. Mehta, Xiaobai Li, Yuri Kotliarov, Mohammad Naqi, Angelique Biancotto, Sarfaraz Hasni, Rongye Shi, Yenealem Temesgen-Oyelakin, Jinguo Chen, Donald E Thomas, Isabel Ochoa-Navas, Alan T. Remaley, Sarthak Gupta, Foo Cheung, Massimo Gadina, Huizhi Zhou, Wanxia Li Tsai, Philip M. Carlucci, John J. O'Shea, Mariana J. Kaplan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Nature Communications
Nature Communications
Increased risk of premature cardiovascular disease (CVD) is well recognized in systemic lupus erythematosus (SLE). Aberrant type I-Interferon (IFN)-neutrophil interactions contribute to this enhanced CVD risk. In lupus animal models, the Janus kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dee9ee9d9e4e4fc34a285087b8e0f4bc
http://hdl.handle.net/11386/4766268
http://hdl.handle.net/11386/4766268
Autor:
Carlos Simón, Sandy Clark, Inmaculada Moreno, Erica E. Marsh, Günter P. Wagner, Hugh S. Taylor, J. Julie Kim, Kami Silk, Missy Lavender, Iolanda Garcia-Grau, Peter K. Gregersen, Aoife Kilcoyne, Serdar E. Bulun, Linda G. Griffith, Christine N. Metz, Elnur Babayev, Hilary O. D. Critchley, Jacqueline A. Maybin, Marni Sommer, Kristen A. Matteson, Ridhi Tariyal
Publikováno v:
Critchley, H O D, Babayev, E, Bulun, S, Clark, S, Garcia-Grau, I, Gregersen, P K, Kilcoyne, A, Kim, J J, Lavender, M, Marsh, E E, Matteson, K A, Maybin, J A, Moreno, I, Silk, K, Sommer, M, Simón, C, Tariyal, R, Taylor, H S, Wagner, G P & Griffith, L G 2020, ' Menstruation: science and society ', American Journal of Obstetrics and Gynecology . https://doi.org/10.1016/j.ajog.2020.06.004
Elsevier
Elsevier
© 2020 The Authors Women's health concerns are generally underrepresented in basic and translational research, but reproductive health in particular has been hampered by a lack of understanding of basic uterine and menstrual physiology. Menstrual he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d8f04ef5badcd152a5d0f7a08fec15d
https://hdl.handle.net/20.500.11820/30fdc5fd-cfa9-46b0-83c6-58ddbe7a1865
https://hdl.handle.net/20.500.11820/30fdc5fd-cfa9-46b0-83c6-58ddbe7a1865
Autor:
Peter S. Linsley, Betsy J. Barnes, Peter K. Gregersen, Kirsten E. Diggins, Dan Li, Victoria Nelson, Kim R. Simpfendorfer, Su Song, Bharati Matta
Genetic variants within or near the interferon regulatory factor 5 (IRF5) locus associate with systemic lupus erythematosus (SLE) across ancestral groups. The major IRF5-SLE risk haplotype is common across populations, yet immune functions for the ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f5bdd904399de05c28ae84db79d1c7
https://europepmc.org/articles/PMC7098722/
https://europepmc.org/articles/PMC7098722/
Autor:
Yajing Gao, Chaoying Liang, Bernard Lauwerys, Benjamin E. Wakeland, Linley Riediger, Nancy J. Olsen, Igor Dozmorov, Quan Zhen Li, Carlos Arana, Xiaoxia Zuo, Patrick M. Gaffney, Prithvi Raj, Gary S. Gilkeson, Jinchun Zhou, Joel M. Guthridge, Peter K. Gregersen, Dong-Jae Jun, Ran Song, Betty P. Tsao, Honglin Zhu, Jennifer A. Kelly, David R. Karp, Judith A. James, Swapan K. Nath, Bo Zhang, Chandrashekhar Pasare, Nicolai S. C. van Oers, Edward K. Wakeland
Publikováno v:
Genome biology, Vol. 21, no.1, p. 281 [1-26] (2020)
Genome Biology
Genome Biology, Vol 21, Iss 1, Pp 1-26 (2020)
Genome Biology
Genome Biology, Vol 21, Iss 1, Pp 1-26 (2020)
BackgroundSystemic lupus erythematosus (SLE) is a clinically heterogeneous autoimmune disease characterized by the development of anti-nuclear antibodies. Susceptibility to SLE is multifactorial, with a combination of genetic and environmental risk f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be9598291a8eeadeed2379897c0b2f7c
https://hdl.handle.net/2078.1/260417
https://hdl.handle.net/2078.1/260417