Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Periasamy Sundaresan"'
Autor:
Xianjun Zhu, Shujin Li, Lulin Huang, Mu Yang, Zhenglin Yang, Periasamy Sundaresan, Rulian Zhao, Chen Chen
Publikováno v:
Genetic Testing and Molecular Biomarkers. 25:399-404
Background: Familial exudative vitreoretinopathy (FEVR), a group of rare inherited retinal vascular disorders, is the major cause of vision loss in juveniles. At present, the diagnosis of FEVR rema...
Autor:
Vijayalakshmi Perumalsamy, Rupa Anjanamurthy, Periasamy Sundaresan, Devarajan Bharanidharan, Ayyasamy Vanniarajan, Sriee Viswarubhiny
Publikováno v:
Eye and Vision, Vol 8, Iss 1, Pp 1-11 (2021)
Eye and Vision
Eye and Vision
Background Leber congenital amaurosis (LCA), primarily characterized by retinal degeneration is the most severe form of inherited retinal dystrophy (IRD) responsible for congenital blindness. The presence of phenotypic heterogeneity makes the diagnos
Autor:
Preeti Gupta, Maryam Hazly Hilmy, Jie Jin Wang, Jiemin Liao, Allan Fong, Maria K. Swift, Johanna M. Colijn, Paul Mitchell, Ya Xing Wang, Anita S Y Chan, Barbara E.K. Klein, Pirro G. Hysi, Jaeyoon Chung, Emily Y. Chew, Wanting Zhao, Yang Shen, Ava Grace Tan, Hengtong Li, Eranga N. Vithana, Gyungah Jun, Wenting Liu, Tin Aung, Qiao Fan, Yuan Shi, Ekaterina Yonova-Doing, Soon-Phaik Chee, Sudha K. Iyengar, Yik Ying Teo, Periasamy Sundaresan, Chiea Chuen Khor, Zheng Li, Kathryn P. Burdon, Miao Ling Chee, Yih Chung Tham, Christopher J Hammond, Xiaoran Chai, Kerrin S. Small, Queenie S. Tan, Jacqueline Chua, Jost B. Jonas, Astrid E. Fletcher, Alexessander Couto Alves, Pieter W.M. Bonnemaijer, Ravilla D. Ravindran, Mei Chin Lee, Milly S. Tedja, Robert P. Igo, Kristine E. Lee, Tien Y Wong, Xinyi Su, Caroline C W Klaver, Xueling Sim, Ching-Yu Cheng, Chaolong Wang, Lars G. Fritsche
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-8 (2020)
Communications Biology, 3(1):755. Springer Nature
Communications Biology, 3
Communications Biology, 3, 1
Communications Biology
Communications Biology, 3(1):755. Springer Nature
Communications Biology, 3
Communications Biology, 3, 1
Communications Biology
Nuclear cataract is the most common type of age-related cataract and a leading cause of blindness worldwide. Age-related nuclear cataract is heritable (h2 = 0.48), but little is known about specific genetic factors underlying this condition. Here we
Autor:
Shih-Jen Chen, Marco Yu, Prabhat Nangia, Se Woong Kang, Jonathan C.H. Chan, Suganeswari Ganesan, Chui Ming Gemmy Cheung, Xiaohui Yang, Praveen Vashist, Gyulli M. Kazakbaeva, Ramasamy Kim, Charumathi Sabanayagam, Vaitheeswaran Kulothungan, Pei Quan Zhao, Astrid E. Fletcher, Jost B. Jonas, Fumihiko Matsuda, Rajiv Raman, Tung-Mei Kuang, Ravilla D. Ravindran, Kohta Fujiwara, Kenji Yamashiro, Nattapol Pokawattana, Ronnie George, Raba Thapa, Achareeya Saenmee, Rohit C Khanna, Kyu Hyung Park, Akitaka Tsujikawa, Tien Yin Wong, Jie Hao, Jae Pil Shin, Masahiro Miyake, Sang Jun Park, Kai Cao, Feifei Mao, Tarun Sharma, Ningli Wang, Songhomitra Panda-Jonas, Janani Surya, Ayako Takahashi, Takamasa Kayama, Timur R. Gilmanshin, Hyun Woong Kim, Ching-Yu Cheng, Jaeryung Oh, Ya Xing Wang, Tyler Hyungtaek Rim, Wen Bin Wei, Hiroyuki Namba, Watanee Jenchitr, Toru Takebayashi, Ryo Kawasaki, Sei Harada, Mariko Sasaki, Mukharram M. Bikbov, Koh Hei Sonoda, Periasamy Sundaresan, Qianli Meng, Vinay Nangia, Ian Y. H. Wong, Yasuo Yanagi, Hidetoshi Yamashita, Paisan Ruamviboonsuk, Usha Chakravarthy, Rinat M. Zainullin, Yih Chung Tham, Timur A. Khalimov, Seung-Young Yu, G.H.M.B. van Rens
Publikováno v:
Ophthalmology. 127:1371-1381
Purpose Although there have been many population-based studies of age-related macular degeneration (AMD), only limited information is available in Asia on the epidemiology of geographic atrophy (GA). We aimed to determine the prevalence and patterns
Autor:
Lulin Huang, Xiong Zhu, Kuanxiang Sun, Shi Ma, Zhenglin Yang, Periasamy Sundaresan, Fang Hao, Xianjun Zhu
Publikováno v:
Genetic Testing and Molecular Biomarkers. 24:92-98
Background: Familial exudative vitreoretinopathy (FEVR) is an inheritable retinal vascular disease, which often leads to severe vision loss and blindness in children. However, reported mutations can only account for 50-60% of patients with FEVR. The
Autor:
Yi Huang, Fang Hao, Ye Yuan, Shi Ma, Zhenglin Yang, Xiang Zhang, Peiquan Zhao, Ping Fei, Xianjun Zhu, Yeming Yang, Shanshan Zhang, Xiong Zhu, Mu Yang, Hui-Juan Xu, Lulin Huang, Lin Zhang, Periasamy Sundaresan, Weiquan Zhu, Shujin Li
Publikováno v:
J Clin Invest
Familial exudative vitreoretinopathy (FEVR) is a severe retinal vascular disease that causes blindness. FEVR has been linked to mutations in several genes associated with inactivation of the Norrin/β-catenin signaling pathway, but these account for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a79a177cc1db7459d85c8be87349ba5
https://europepmc.org/articles/PMC7954601/
https://europepmc.org/articles/PMC7954601/
Autor:
Xianjun Zhu, Shujin Li, Wenjing Liu, Lulin Huang, Kim Ramasamy, Zhenglin Yang, Lin Zhang, Mu Yang, Periasamy Sundaresan, Yeming Yang, Zhilin Jiang, Yu Zhou
Publikováno v:
Human Molecular Genetics. 27:2563-2572
Retinitis pigmentosa (RP) refers to a group of retinal degenerative diseases, which often lead to vision loss. Although 70 genes have been identified in RP patients, the genetic cause of approximately 30% of RP cases remains unknown. We aimed to iden
Autor:
Desmond Quek, Tin Aung, Periasamy Sundaresan, Mani Baskaran, Tien Yin Wong, Tina T. Wong, Rengaraj Venkatesh, Subbiah. R. Krishnadas, Monisha E. Nongpiur, David Goh, Pui Yi Boey, John J.B. Allen, Eranga N. Vithana, Srinivasan Kavitha, Shamira A. Perera, Roopam Duvesh, Chiea Chuen Khor, Ching-Yu Cheng, Rahat Husain, Ching Lin Ho, Saravanan Vijayan
Publikováno v:
Ophthalmology. 125:664-670
To investigate whether newly identified genetic loci for primary angle-closure glaucoma (PACG) are associated with early stage angle-closure disease defined as primary angle closure suspect (PACS).Case-control study.A total of 1397 PACS patients and
Autor:
Ganesh Raman, Premanand Chandran, Prasanna Venkataraman, Prakash Chermakani, Siva Prasanna Thilagar, Periasamy Sundaresan
Publikováno v:
Ophthalmic Genetics. 40:185-187
Traboulsi syndrome is a rare genetic disorder, inherited in an autosomal recessive fashion. It is characterized by facial dysmorphism, lens dislocation, anterior-segment abnormalities, and spontane...
Publikováno v:
Mitochondrion. 36:21-28
Leber's hereditary optic neuropathy (LHON) is a mitochondrial DNA (mtDNA) associated neurodegenerative disorder of retinal ganglion cells. In this study, whole mitochondrial genome sequencing of 75 LHON patients and 40 controls was performed to ident