Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Pam Hall"'
Publikováno v:
Kidney International. 95:363-374
Platelet-leukocyte interactions promote acute glomerulonephritis. However, neither the nature of the interactions between platelets and immune cells nor the capacity of platelets to promote leukocyte activation has been characterized in this conditio
Autor:
Kirstin Elgass, Brodie C. Smith, Hang Fai Kwok, Janet L. Wee, Louisa Yeung, Mark D. Wright, Wendy Dankers, Yuxin S Liu, Michael J. Hickey, Michaela Finsterbusch, Maria C. Demaria, Pam Hall, Jeremy M L Anderson, Ian P. Wicks
Publikováno v:
Journal of immunology (Baltimore, Md., 205(2), 521-532. American Association of Immunologists
The importance of tetraspanin proteins in regulating migration has been demonstrated in many diverse cellular systems. However, the function of the leukocyte-restricted tetraspanin CD53 remains obscure. We therefore hypothesized that CD53 plays a rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118ebf7f50a7a86d71b3e51061eeffbf
https://pure.amc.nl/en/publications/leukocyte-tetraspanin-cd53-restrains-3-integrin-mobilization-and-facilitates-cytoskeletal-remodeling-and-transmigration-in-mice(78b71bad-3c6e-4263-b591-c807cad79ce7).html
https://pure.amc.nl/en/publications/leukocyte-tetraspanin-cd53-restrains-3-integrin-mobilization-and-facilitates-cytoskeletal-remodeling-and-transmigration-in-mice(78b71bad-3c6e-4263-b591-c807cad79ce7).html
Autor:
Annemiek B. van Spriel, Mark D. Wright, Frank Alderuccio, Eleanor L. Jones, Louisa Yeung, Michael J. Hickey, Andrew Newman, Hang Fai Kwok, Katrina J. Binger, Zeyad Nasa, Ann Ager, Maria C. Demaria, Rens Peeters, Brodie C. Smith, Janet L. Wee, G. J. Hämmerling, Masa Mihaljcic, Pam Hall
Publikováno v:
iScience, Vol 23, Iss 5, Pp-(2020)
iScience
iScience, 23
iScience, 23, 5
iScience
iScience, 23
iScience, 23, 5
Summary Tetraspanins regulate key processes in immune cells; however, the function of the leukocyte-restricted tetraspanin CD53 is unknown. Here we show that CD53 is essential for lymphocyte recirculation. Lymph nodes of Cd53−/− mice were smaller
Autor:
Stephen R. Holdsworth, Anqi Li, Sharon L. Ford, Maliha A. Alikhan, Clare L. V. Westhorpe, Charles R. Mackay, A. Richard Kitching, Joshua D. Ooi, Sven H. Loosen, Jonathan Dick, Trent M. Woodruff, Dragana Odobasic, Michael J. Hickey, Poh-Yi Gan, Pam Hall
Publikováno v:
Kidney International. 93:615-625
The prospects for complement-targeted therapy in ANCA-associated vasculitis have been enhanced by a recent clinical trial in which C5a receptor 1 (C5aR1) inhibition safely replaced glucocorticoids in induction treatment. C5aR1 primes neutrophils for
Autor:
A. Richard Kitching, Anqi Li, Clare L. V. Westhorpe, Pam Hall, Songhui Li, Camden Lo, Zhe Hao Tan, M. Ursula Norman, Susan K. Nilsson, Sarah L. Snelgrove, Michael J. Hickey, Michaela Finsterbusch
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
Although effector CD4+ T cells readily respond to antigen outside the vasculature, how they respond to intravascular antigens is unknown. Here we show the process of intravascular antigen recognition using intravital multiphoton microscopy of glomeru
Publikováno v:
Journal of Leukocyte Biology
Emerging evidence has revealed that noradrenaline (NA), the main neurotransmitter of the sympathetic nervous system (SNS), regulates a variety of immune functions via binding to adrenergic receptors present on immune cells. In this study, we examined
Autor:
Pam Hall, A. Richard Kitching, James E. Bayard, Kim M. O’Sullivan, Qiang Cheng, Clare L. V. Westhorpe, Michael J. Hickey
Publikováno v:
The American Journal of Pathology. 187:318-331
Neutrophil extracellular traps (NETs) have been documented in glomeruli of patients with glomerulonephritis. However, the dynamics of NET formation in the glomerulus and their functional contribution to acute glomerular injury are poorly understood.
Autor:
Anqi Li, A. Richard Kitching, Clare L. V. Westhorpe, Michael J. Hickey, Sapna Devi, Michaela Finsterbusch, Pam Hall
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Nonclassical monocytes undergo intravascular patrolling in blood vessels, positioning them ideally to coordinate responses to inflammatory stimuli. Under some circumstances, the actions of monocytes have been shown to involve promotion of neutrophil
Autor:
Cecilia Lo, Sarah L. Snelgrove, Pam Hall, Toby Coates, Richard R. Kitching, Michael J. Hickey, Maliha A. Alikhan, Camden Lo, Stephen R. Holdsworth
Publikováno v:
Transplantation. 101(5)
The healthy kidney contains an extensive population of renal mononuclear phagocytes (RMPs), with substantial phenotypic and functional diversity. However, how this diverse population is affected by ischemia-reperfusion injury (IRI), an obligate part
Autor:
Lauren Florence Young, Pam Hall, Rain Y.Q. Kwan, John J. Emmins, Leanne M Cordner, Julian I. Rood, Michael J. Hickey, Dena Lyras, Milena M. Awad, Catherine Kennedy
Publikováno v:
PLoS Pathogens
Monash University
PLoS Pathogens, Vol 4, Iss 4, p e1000045 (2008)
Monash University
PLoS Pathogens, Vol 4, Iss 4, p e1000045 (2008)
Reduced tissue perfusion leading to tissue ischemia is a central component of the pathogenesis of myonecrosis caused by Clostridium perfringens. The C. perfringens α-toxin has been shown capable of inducing these changes, but its potential synergy w