Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jiil Chung"'
Autor:
Cynthia Hawkins, Daniel A. Morgenstern, Victoria J. Forster, Scott Lindhorst, Sumedha Sudhaman, Uri Tabori, An Van Damme, Eric Bouffet, Alexander Lossos, Ben George, Annika Bronsema, Anita Villani, Michael Osborn, Annie Huang, Yosef E. Maruvka, Melyssa Aronson, Patrick Tomboc, Michal Yalon-Oren, David S. Ziegler, Reid Hayes, Carol Durno, Vanessa Bianchi, Melissa Galati, Nuno Miguel Nunes, Magimairajan Issai Vanan, Vanja Cabric, Gregory Thomas, Nicholas Light, Scott Davidson, Matthew Zatzman, Michael D. Taylor, A. Sorana Morrissy, Martin Komosa, Melissa Edwards, Gary Mason, Jiil Chung, Adam Shlien, Gad Getz, Shriya Deshmukh, Alyssa Reddy, Karl P. Hodel, Zachary F. Pursell, Robert Siddaway, Maura Massimino, Enrico Opocher, Ledia Brunga, David Malkin, Ben Ho, Jacalyn Kelly, Daniel C. Bowers, Nathaniel D. Anderson, Valerie Larouche, Thomas A. Kunkel, Nicholas J. Haradhvala, Kristina A. Cole
Publikováno v:
Cancer Discov
Cancer discovery, Vol. 11, no. 5, p. 1176-1191 (2021)
Cancer discovery, Vol. 11, no. 5, p. 1176-1191 (2021)
Although replication repair deficiency, either by mismatch repair deficiency (MMRD) and/or loss of DNA polymerase proofreading, can cause hypermutation in cancer, microsatellite instability (MSI) is considered a hallmark of MMRD alone. By genome-wide
Autor:
Jonathan N. Byrd, James G. Jackson, Cynthia Hawkins, Alberto Martin, Uri Tabori, Walter J. Zahurancik, Dana Elshaer, Cynthia J. Guidos, Melissa Galati, Sumedha Sudhaman, Oz Mordechai, Ayse Bahar Ercan, Tomasz Sarosiek, Melyssa Aronson, Miki S. Gams, Victoria J. Forster, Taylor Bridge, Eric Bouffet, Andrea H. Seeley, Carol Durno, Melissa Edwards, Nathan Ungerleider, Vivian S. Park, Adam Shlien, Zachary F. Pursell, Lazar Joksimovic, Robert Siddaway, Nuno Miguel Nunes, Xia Wang, Zucai Suo, Iram Siddiqui, Jagadeesh Ramdas, Gavin P. Dunn, Jiil Chung, Richard de Borja, Karl P. Hodel
Publikováno v:
Cancer Research. 80:5606-5618
POLE mutations are a major cause of hypermutant cancers, yet questions remain regarding mechanisms of tumorigenesis, genotype–phenotype correlation, and therapeutic considerations. In this study, we establish mouse models harboring cancer-associate
Autor:
Rodney H. Breau, Andrew Matthew, Janet Papadakos, Jiil Chung, Jackie Bender, David Guttman, Robin Morash, Jennifer M. Jones, Girish S. Kulkarni
Publikováno v:
Supportive Care in Cancer
Background To date, little research has examined the quality of life and cancer-associated needs of bladder cancer patients. The objective of the current study was to assess the quality of life (QoL), informational needs, and supportive care needs (S
Autor:
Robin Morash, Jiil Chung, Rodney H. Breau, David Guttman, Andrew Matthew, Manjula Maganti, Girish S. Kulkarni, Jennifer M. Jones, Janet Papadakos, Jackie Bender
Publikováno v:
Bju International
Objective To examine health behaviours in bladder cancer survivors including physical activity (PA), body mass index, diet quality, smoking and alcohol consumption, and to explore their relationship with health‐related quality of life (HRQoL). Subj
Autor:
Michael Osborn, Ronit Elhasid, Adam Shlien, Valerie Larouche, Zachary F. Pursell, Tanner M. Johanns, Melyssa Aronson, Gavin P. Dunn, David S. Ziegler, Scott Lindhorst, Daniel C. Bowers, Rina Dvir, Theodore W. Laetsch, Scott Davidson, John M. Maris, Peter B. Dirks, Richard de Borja, Michael D. Taylor, Christian P. Kratz, Cynthia Hawkins, Zucai Suo, Eric Bouffet, Roula Farah, Shlomi Constantini, Joseph F. Costello, Tatiana Lipman, Vijay Ramaswamy, Uri Tabori, Julia A. Elvin, David Fabrizio, Ivan Smirnov, Melissa Edwards, Magnus Sabel, Pichai Raman, Phillip B. Storm, Vanan Magimairajan Issai, Matthew R. Grimmer, Melissa Galati, Gideon Rechavi, Jiil Chung, Fabio Fuligni, Katharina Wimmer, Annika Bronsema, Karl P. Hodel, David Malkin, Kristina A. Cole, Carol Durno, David Samuel, Duncan Stearns, Enrico Opocher, Michal Yalon, Nicholas Light, M. Stephen Meyn, Ben George, Meredith S. Irwin, Annie Huang, Matthew Zatzman, Helen Toledano, Brittany Campbell, Gregory Thomas, Walter J. Zahurancik, Gary Mason
Publikováno v:
Cell, vol 171, iss 5
We present an extensive assessment of mutation burden through sequencing analysis of >81,000 tumors from pediatric and adult patients, including tumors with hypermutation caused by chemotherapy, carcinogens, or germline alterations. Hypermutation was