Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Je Kyung Seong"'
Autor:
Je Kyung Seong, Ho Keun Kwon
Publikováno v:
Mammalian Genome
Laboratory mice have long been an invaluable tool in biomedical science and have made significant contributions in research into life-threatening diseases. However, the translation of research results from mice to humans often proves difficult due to
Autor:
Pattawika Lertpatipanpong, Seung Yeon Oh, Thomas E. Eling, Jae-Hak Lee, Je Kyung Seong, Seung Joon Baek, Ilju Kim
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports
Scientific Reports
Nonsteroidal anti-inflammatory drug-activated gene-1 (NAG-1) plays a role in various diseases. Here, the anti-diabetic effects of NAG-1 were evaluated using a high-fat diet/streptozotocin-induced diabetic mouse model. NAG-1-overexpressing transgenic
Autor:
Je Kyung Seong, Maria Raquel Rojas Jimenez, Mi Young Kim, Yun Soo Bae, Il Yong Kim, Soo Young Cho, Yo Na Kim, Dong Soo Kyeong, Jae Hoon Shin, Hee Jung Lim, Mi-Ock Lee
Publikováno v:
Experimental & Molecular Medicine
The AHNAK nucleoprotein has been determined to exert an anti-obesity effect in adipose tissue and further inhibit adipogenic differentiation. In this study, we examined the role of AHNAK in regulating hepatic lipid metabolism to prevent diet-induced
Autor:
Sung Sik Choe, Hye Jeong Kim, Tae Wook Nam, Yul Ji, Jae Woo Kim, Chan Bae Park, In Hye Lee, Young Jin, Heeju Na, Jae Bum Kim, Ki Taek Nam, Yong Geun Jeon, Yaechan Song, Han Woong Lee, Je Kyung Seong, Daehee Hwang, Hahn Nahmgoong, Sung Min Kim
Publikováno v:
Diabetes
Becn1/Beclin-1 is a core component of the class III phosphatidylinositol 3-kinase required for autophagosome formation and vesicular trafficking. Although Becn1 has been implicated in numerous diseases such as cancer, aging, and neurodegenerative dis
Autor:
Chang Woo Chae, Ho Jae Han, Jun Sung Kim, Seo Yihl Kim, Jae Ryong Lim, Young Hyun Jung, Hyun Jik Lee, Je Kyung Seong, In Koo Hwang, Gee Euhn Choi
Publikováno v:
Br J Pharmacol
Background and purpose Although diabetes mellitus (DM) is an important risk factor for Alzheimer's disease (AD), the detailed mechanism(s) by which DM regulates amyloid β (Aβ) processing is still unclear. The longer residence time of amyloid precur
Autor:
Hyun Jung Kwon, Abhirup Saha, Minsu Kim, Yeonho Son, Woo Ram Yang, Jin Hyun Jeong, Je Kyung Seong, Yun Hee Lee, Young Suk Jung, Yoon Keun Cho, Sang Yeop Ahn
Publikováno v:
International Journal of Obesity. 45:122-129
Polymethoxyselenoflavone (PMSF) is a compound that substitutes the oxygen atom in a flavonoid with selenium. This study aimed to investigate the effects of PMSFs on lipid metabolism in adipocytes and their anti-obesity potential. To test lipolytic an
Autor:
Jae Young Choi, Moo Suk Park, Yoon Kyung Jeon, Ji-Hwan Ryu, Young-Min Hyun, Jinhong Park, Doona Song, Mia Gi, Gyoonhee Han, Wan Namkung, Eun Hye Lee, Mi Hwa Shin, Je Kyung Seong
Publikováno v:
Theranostics
Rationale: Pendrin is encoded by SLC26A4 and its mutation leads to congenital hearing loss. Additionally, pendrin is up-regulated in inflammatory airway diseases such as chronic obstructive pulmonary disease, allergic rhinitis, and asthma. In this st
Autor:
Hui-Young Lee, Seul Gi Yoon, Ki Taek Nam, Jihye Yoo, Je Kyung Seong, Hyun Ju Seo, Yejin Cho, Soojin Son, Jun-Young Seo, Ku Sul Kim, Jeong Jin Kim, Kyung Mi Choi, Haengdueng Jeong, Peter Cresswell, Il Yong Kim, John Eom, Jae Bong Lee
Publikováno v:
Proceedings of the National Academy of Sciences. 116:17419-17428
Viperin is an interferon (IFN)-inducible multifunctional protein. Recent evidence from high-throughput analyses indicates that most IFN-inducible proteins, including viperin, are intrinsically expressed in specific tissues; however, the respective in
Publikováno v:
BMB Reports
The present study evaluated the role of AHNAK in Bartonella henselae infection. Mice were intraperitoneally inoculated with 2 × 108 colony-forming units of B. henselae Houston-1 on day 0 and subsequently on day 10. Blood and tissue samples of the mi
Autor:
Sung Hwa Yoon, Jun Gi Rho, Ki Woo Kim, Hanho Shin, Dong Hwee Son, Ji Hye Han, Wook Kim, Ju Young Park, Je Kyung Seong
Publikováno v:
The FASEB Journal. 33:4314-4326
The overactivity of cannabinoid 1 receptor (CB1R) is associated with obesity and type 2 diabetes. First-generation CB1R antagonists, such as rimonabant, offered therapeutic advantages for the control of obesity and related metabolic abnormalities, bu