Zobrazeno 1 - 10
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pro vyhledávání: '"François Mallet"'
Pubertal immune challenge suppresses the hypothalamic-pituitary-gonadal axis in male and female mice
Autor:
Chantal Matar, Jeffrey D. Blaustein, Jacky Liang, Rajini Chandrasegaram, Jean-François Mallet, Kevin B. Smith, Nafissa Ismail, Emma Murray
Publikováno v:
Brain Research Bulletin. 170:90-97
Kisspeptin is a neuropeptide responsible for propagating the hypothalamic-pituitary-gonadal (HPG) axis and initiating puberty. Pubertal exposure to an immune challenge causes enduring sexual behavior dysfunction in males and females, but the mechanis
Autor:
Fabienne Allias, Benoit You, Touria Hajri, Mojgan Devouassoux-Shisheboran, François Mallet, François Golfier, Jérôme Massardier, Sophie Patrier, Jonathan Lopez, Pierre-Adrien Bolze
Publikováno v:
Gynecologic Oncology
Gynecologic Oncology, 2020, 158, pp.785-793. ⟨10.1016/j.ygyno.2020.05.042⟩
Gynecologic Oncology, Elsevier, 2020, 158, pp.785-793. ⟨10.1016/j.ygyno.2020.05.042⟩
Gynecologic Oncology, 2020, 158, pp.785-793. ⟨10.1016/j.ygyno.2020.05.042⟩
Gynecologic Oncology, Elsevier, 2020, 158, pp.785-793. ⟨10.1016/j.ygyno.2020.05.042⟩
International audience; Objective: Using a transcriptional approach on tissue samples, we sought to identify predictive biomarkers of post molar malignant transformation, and of choriocarcinoma chemosensitivity to mono- (methotrexate or actinomycin D
Autor:
Julien Textoris, Fabienne Venet, Andrew Hemmert, Virginie Moucadel, Laurence Vachot, Sophie Blein, Dina M. Tawfik, Adeline Bocquet, Thomas Rimmelé, François Mallet, Alexandre Pachot, Javier Yugueros-Marcos, Guillaume Monneret, Montgomery Jesse Linton, Karen Brengel-Pesce
Publikováno v:
The Journal of Infectious Diseases
Background Critical illness such as sepsis is a life-threatening syndrome defined as a dysregulated host response to infection and is characterized by patients exhibiting impaired immune response. In the field of diagnosis, a gap still remains in ide
Autor:
Mélanie Denizot, Elisabeth Cerrato, Alexandre Pachot, François Mallet, Fabienne Venet, Julien Textoris, Marine Mommert, Guy Oriol, Guillaume Monneret, Valérie Cheynet, Karen Brengel-Pesce, Audrey Guichard, Olivier Tabone, Alain Lepape
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-15 (2020)
Critical Care
Critical Care
Background Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. Numerous studies have explored the complex and dynamic transcriptome modulations observed in sepsis patients, but a large fracti
Autor:
Nafissa Ismail, Jasmine Rooke, Spencer van Mil, Jean-François Mallet, Bronwen J. Thomas, Chantal Matar, Rupali Sharma, Brett Melanson, Jaclyn M. Schwarz
Publikováno v:
The Journal of Immunology. 202:2131-2140
Puberty is a critical period of development marked by sexual, immune, and neural maturation. Exposure to stress during this period can lead to enduring changes in brain functioning and in behavior; however, the underlying mechanisms and the programmi
Autor:
Andrew Hemmert, Alexandre Belot, Jean-Baptiste Fassier, Etienne Javouhey, Matthew Hockin, Magali Perret, Karen Brengel-Pesce, Sophie Trouillet-Assant, Mehdi Mezidi, François Mallet, Marine Mommert, Sébastien Viel, Jean-Christophe Richard
Publikováno v:
European Journal of Immunology
European Journal of Immunology, 2021, 51 (4), pp.989-994. ⟨10.1002/eji.202048978⟩
European Journal of Immunology, 2021, 51 (4), pp.989-994. ⟨10.1002/eji.202048978⟩
Low concentrations of type‐I interferon (IFN) in blood seem to be associated with more severe forms of Coronavirus disease 2019 (COVID‐19). However, following the type‐I interferon response (IR) in early stage disease is a major challenge. We e
Autor:
Elisabeth Cerrato, François Mallet, Karen Brengel-Pesce, François Bartolo, William Mouton, Evangelos J. Giamarellos-Bourboulis, Sophie Trouillet-Assant, Chloé Albert Vega, Eleni Karakike
Publikováno v:
Clinical immunology (Orlando, Fla.). 226
Lipopolysaccharide (LPS) and monophosphoryl lipid A (MPLA) induce, overall, similar transcriptional profiles in healthy individuals, although LPS has been shown to more potently induce pro-inflammatory cytokines. We explore herein whether MPLA could
Autor:
Fabienne Venet, François Mallet, Jonathan Lopez, Sophie Trouillet-Assant, Guillaume Monneret, Véronique Leray, Alexandre Pachot, François Bartolo, Karen Brengel-Pesce, Chloé Albert Vega, Julien Textoris, Thomas Rimmelé, Benjamin Delwarde, Guy Oriol
Publikováno v:
Scientific Reports
Scientific Reports, 2020, 10 (1), pp.16136. ⟨10.1038/s41598-020-73014-2⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, 2020, 10 (1), pp.16136. ⟨10.1038/s41598-020-73014-2⟩
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The complexity of sepsis pathophysiology hinders patient management and therapeutic decisions. In this proof-of-concept study we characterised the underlying host immune response alterations using a standardised immune functional assay (IFA) in order
Autor:
Karen Brengel-Pesce, Guy Oriol, Sophie Trouillet-Assant, William Mouton, Julien Textoris, Chloé Albert-Vega, François Bartolo, Alexandre Pachot, Mathilde Boccard, François Mallet, Jonathan Lopez
Publikováno v:
Clinical Immunology
Clinical Immunology, 2020, 210, pp.108312. ⟨10.1016/j.clim.2019.108312⟩
Clinical Immunology, Elsevier, 2020, 210, pp.108312-. ⟨10.1016/j.clim.2019.108312⟩
Clinical Immunology, 2020, 210, pp.108312. ⟨10.1016/j.clim.2019.108312⟩
Clinical Immunology, Elsevier, 2020, 210, pp.108312-. ⟨10.1016/j.clim.2019.108312⟩
Recent advances in the immunotherapy field require evaluation of the immune function to adapt therapeutic decisions. Immune functional assays (IFA) are able to reveal the immune status and would be useful to further adapt/improve patient’s care. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07c99680e6b279b727c6bb773d80285f
https://hal.science/hal-03489061/document
https://hal.science/hal-03489061/document
Publikováno v:
Frontiers in Public Health
Frontiers in Public Health, Vol 8 (2020)
Frontiers in Public Health, Vol 8 (2020)
Influenza A viruses are amongst the most challenging viruses that threaten both human and animal health. Constantly evolving and crossing species barrier, the emergence of novel zoonotic pathogens is one of the greatest challenges to global health se