Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Dilraj Lama"'
Autor:
Dilraj Lama, Xin Yu Koh, Le-Ann Hwang, Xiao Hui Koh, David P. Lane, Fernando J. Ferrer, Siti Aishah Binte Rahmat
Publikováno v:
Oncogene. 38:7342-7356
Recepteur d'origine nantais (RON) receptor tyrosine kinase (RTK) and its ligand, serum macrophage-stimulating protein (MSP), are well-established oncogenic drivers for tumorigenesis and metastasis. RON is often found to be alternatively spliced resul
Autor:
Dilraj Lama, Chandra S. Verma
Publikováno v:
Protein Sci
The mRNA cap-binding oncoprotein "eIF4E" is phosphorylated at residue S209 by Mnk kinases, and is closely associated with tumor development and progression. Despite being well-established, mechanistic details at the molecular level of mRNA recognitio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f846c10e517344071ffa9b8996559e6
https://europepmc.org/articles/PMC7255503/
https://europepmc.org/articles/PMC7255503/
Autor:
Pieter Johan Adam Eichhorn, Wen Jing Sim, Peter ten Dijke, Tuan Zea Tan, Alan Prem Kumar, Dilraj Lama, Camelia Radulescu, Mathieu Rouanne, Eytan Domany, Hsien Chun Ng, Chandra S. Verma, Hong Koo Ha, Patrick Jaynes, Sarah Kit Leng Lui, Jean Paul Thiery, Dennis Kappei, Azad Saei, Prasanna Vasudevan Iyengar, Lior Haviv-Shapira
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
PubMed Central
DOAJ-Articles
Datacite
UnpayWall
ORCID
Microsoft Academic Graph
Nature Communications
Nature Communications, 10
PubMed Central
DOAJ-Articles
Datacite
UnpayWall
ORCID
Microsoft Academic Graph
Nature Communications
Nature Communications, 10
Treatment of muscle-invasive bladder cancer remains a major clinical challenge. Aberrant HGF/c-MET upregulation and activation is frequently observed in bladder cancer correlating with cancer progression and invasion. However, the mechanisms underlyi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71c089128a660ae6f7f5c3da67bdddd1
https://hdl.handle.net/1887/120659
https://hdl.handle.net/1887/120659
Autor:
Mohan R. Pradhan, Dilraj Lama, Chee Keong Kwoh, Chandra S. Verma, Rohan S. Eapen, Thomas L. Joseph, Christopher J. Brown, David P. Lane
Publikováno v:
Structure. 25:188-194
Ligand binding pockets in proteins contain water molecules, which play important roles in modulating protein-ligand interactions. Available crystallographic data for the 5′ mRNA cap-binding pocket of the translation initiation factor protein eIF4E
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1865:129775
Background Intrinsically disordered regions (IDRs) in proteins can regulate their activity by facilitating protein-protein interactions (PPIs) as exemplified in the recruitment of the eukaryotic translation initiation factor 4E (eIF4E) protein by the
Autor:
Chandra S. Verma, Yu-Keung Mok, Dilraj Lama, Kang Wei Tan, Van Sang Nguyen, Karthik Ramesh, Fook Tim Chew
Publikováno v:
Structure. 26:1178-1186.e3
Despite being initially identified in the blood filtrate, LEKTI is a 15-domain Kazal-type inhibitor mostly known in the regulation of skin desquamation. In the current study, screening of serine proteases in blood coagulation cascade showed that LEKT