Zobrazeno 1 - 4
of 4
pro vyhledávání: '"David J. Montefusco"'
Autor:
Patrick Roddy, L. Ashley Cowart, David J. Montefusco, Johana M. Lambert, William L. Holland, Andrea K. Anderson, Bao Ngan Tran
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 10, Pp 1328-1340 (2020)
J Lipid Res
J Lipid Res
Sphingolipids have become established participants in the pathogenesis of obesity and its associated maladies. Sphingosine kinase 1 (SPHK1), which generates S1P, has been shown to increase in liver and adipose of obese humans and mice and to regulate
Publikováno v:
Biochemical and Biophysical Research Communications. 504:608-616
Non-alcoholic fatty liver disease (NAFLD) is a major clinical concern and its treatment consumes abundant resources. While accumulation of lipids in hepatocytes initiates the disease, this in itself is not necessarily harmful; rather, initiation of i
Autor:
Arun J. Sanyal, L. Ashley Cowart, David J. Montefusco, Sarah Spiegel, Timothy D. Rohrbach, Pierre Bedossa, Amon Asgharpour, Melissa A. Maczis
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 7, Pp 1311-1322 (2019)
J Lipid Res
J Lipid Res
Nonalcoholic fatty liver disease (NAFLD), a leading cause of liver dysfunction, is a metabolic disease that begins with steatosis. Sphingolipid metabolites, particularly ceramide and sphingosine-1-phosphate (S1P), have recently received attention for
Autor:
Mitchell L. Worley, Adam J. Richards, Yusuf A. Hannun, Xinghua Lu, L. Ashley Cowart, Matthew S. Shotwell, David J. Montefusco
Publikováno v:
Molecular Systems Biology
Perturbing metabolic systems of bioactive sphingolipids with genetic approach Multiple types of “omics” data collected from the system Systems approach for integrating multiple “omics” information Predicting signal transduction information fl