Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Christopher C. Griffith"'
Autor:
Elena V. Semina, Linda M. Reis, Brett Deml, Adi Reich, Christopher C. Griffith, Sarah E Seese, Robyn V. Jamieson
Publikováno v:
Human Mutation
Microphthalmia, coloboma, and aniridia are congenital ocular phenotypes with a strong genetic component but often unknown cause. We present a likely causative novel variant in MAB21L1, c.152G>T p.(Arg51Leu), in two family members with microphthalmia
Autor:
Christopher C. Griffith, Mobeen Rahman
Publikováno v:
Surgical Pathology Clinics. 14:111-126
Salivary duct carcinoma (SDC) is a rare, aggressive salivary gland malignancy with significant mortality. Morphologically, most tumors are characterized by apocrine differentiation with a typical immunophenotype of androgen receptor positive/gross cy
Autor:
Xu Wang, Haydn T. Kissick, Andreas Wieland, Nabil F. Saba, Mihir R. Patel, William H. Hudson, Rafi Ahmed, Christiane S Eberhardt, Zhuo Georgia Chen, Maria Cardenas, Christopher C. Griffith, Rebecca C. Obeng
Publikováno v:
Nature. 597:274-278
Tumours often contain B cells and plasma cells but the antigen specificity of these intratumoral B cells is not well understood1-8. Here we show that human papillomavirus (HPV)-specific B cell responses are detectable in samples from patients with HP
Autor:
Yigu Chen, Melina Flanagan, Christopher C. Griffith, Cindy McGrath, Annemieke van Zante, Ronald Balassanian, Paul A. VanderLaan, Amy J Spiczka, Melissa L. Randolph, Peter B. Illei, Jackie Cuda, Daniel Johnson, Deepu Alex, Jennifer L. Sauter, Jordan P. Reynolds
Publikováno v:
Journal of the American Society of Cytopathology. 9:570-578
Introduction This study aims to improve understanding of the cytopathology community’s perspective regarding the value of rapid onsite evaluation (ROSE) in clinical practice. Materials and methods The American Society of Cytopathology membership wa
Autor:
Christopher C. Griffith, Martin Zenker, William E. Allen, Ganka Douglas, Denise Howting, Eissa Faqeih, Roger B. Sher, Davut Pehlivan, Nigel G. Laing, Henry Houlden, Jennifer E. Stauffer, Naif A.M. Almontashiri, Hamid Galehdari, Paige B. Martin, Ryo Yonashiro, Rajesh Kumar, Tamar Harel, Yu Kigoshi-Tansho, Gregory A. Cox, James R. Lupski, Reza Maroofian, Monique M. Ryan, Gianina Ravenscroft, Neda Mazaheri, Jennifer E. Posey, Tina Müller, Claudio A. P. Joazeiro, Denny Schanze
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
A hallmark of neurodegeneration is defective protein quality control. The E3 ligase Listerin (LTN1/Ltn1) acts in a specialized protein quality control pathway—Ribosome-associated Quality Control (RQC)—by mediating proteolytic targeting of incompl
Autor:
Stacey M. Gargano, Charalambos C. Solomides, Christopher Sebastiano, Kim HooKim, Christopher C. Griffith
Publikováno v:
Cancer Cytopathology. 128:92-99
Background Basaloid salivary gland neoplasms (BSNs), which include benign primary tumors and primary or metastatic malignancies, show overlapping morphology in fine-needle aspiration (FNA). The Milan system recommends assigning a grade (low or high)
Autor:
Kristian Tveten, Sara Ellingwood, Paulien A. Terhal, Kirsty McWalter, Christopher C. Griffith, Marwan Shinawi, Koen L.I. van Gassen, A. Micheil Innes, Rosemarie Smith, Cecilie F. Rustad, David A. Dyment, Matthew A. Lines, Parul Jayakar
Publikováno v:
European Journal of Human Genetics, 27(10), 1611. Nature Publishing Group
European Journal of Human Genetics
European Journal of Human Genetics
The developmental and epileptic encephalopathies (DEE) are a heterogeneous group of chronic encephalopathies frequently associated with rare de novo nonsynonymous coding variants in neuronally expressed genes. Here, we describe eight probands with a
Autor:
Wanqi Chen, Dong M. Shin, Sreenivas Nannapaneni, Andreas Wieland, Rafi Ahmed, Gregory B. Lesinski, Mihir R. Patel, Christopher C. Griffith, Zhengjia Chen, Zhuo Georgia Chen, Nabil F. Saba
Publikováno v:
Head and Neck Pathology. 13:304-312
This study addresses the hypothesis that IL-6/STAT3 signaling is of clinical relevance in oropharyngeal squamous cell carcinoma (OPSCC). We evaluated relationships between key components of this pathway in tumors from a unique cohort of n = 59 fully
Publikováno v:
Head Neck Pathol
Sebaceous lymphadenoma is a rare salivary gland neoplasm most commonly occurring in the sixth to eighth decades of life. Cross sectional imaging typically demonstrates a multicystic expansile mass, most commonly occurring in the parotid gland, where
Autor:
Mihir R. Patel, Christopher C. Griffith, Dongsheng Wang, Dong M. Shin, Sreenivas Nannapaneni, Conor E. Steuer, Yue Lu, Mark W. El-Deiry, Nabil F. Saba, Zhengjia Chen, Xia He, Guoqing Qian, Xu Wang, Zhuo Georgia Chen
Publikováno v:
Oral oncology. 112
Objective We aimed to develop novel combinations of inhibitors targeting EGFR family members and c-Met for the treatment of recurrent SCCHN. Materials and Methods Three different c-Met inhibitors in combination with a pan-HER inhibitor (crizotinib/af