Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Abdullahi Ibrahim Uba"'
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-10
Histone deacetylase (HDAC) 8 has been implicated as a potential therapeutic target in a variety of cancers, neurodegenerative disorders, metabolic dysregulation and autoimmune and inflammatory diseases. Several nonselective HDAC inhibitors have been
Autor:
Kemal Yelekçi, Abdullahi Ibrahim Uba
Publikováno v:
Computational Biology and Chemistry. 77:318-330
Histone deacetylase (HDAC) 6 plays a role in oncogenic transformation and cancer metastasis via tubulin deacetylation, making it a critical target for anticancer drug design. However, lack of selectivity shown by many of the current HDAC6 inhibitors
Autor:
Kemal Yelekçi, Abdullahi Ibrahim Uba
Tubitak Directorate of Research and Development Resources of Kadir Has University Histone deacetylase (HDAC) 10 has been implicated in the pathology of various cancers and neurodegenerative disorders, making the discovery of novel inhibitors of the i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36768b405b51b233cae9a395da5432f7
https://hdl.handle.net/20.500.12469/3473
https://hdl.handle.net/20.500.12469/3473
Methionine Aminopeptidases MetAPs are divalent-cofactor dependent enzymes that are responsible for the cleavage of the initiator Methionine from the nascent polypeptides. MetAPs are classified into two isoforms: namely, MetAP1 and MetAP2. Several stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f2c6a1d9c67bb9ccab14d876e39f3e
https://aperta.ulakbim.gov.tr/record/9023
https://aperta.ulakbim.gov.tr/record/9023
Autor:
Abdullahi Ibrahim Uba, Kemal Yelekçi
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 36:3231-3245
Histone deacetylases (HDACs) have gained increased attention as targets for anticancer drug design and development. HDAC inhibitors have proven to be effective for reversing the malignant phenotype in HDAC-dependent cancer cases. However, lack of sel
Autor:
Usman Muhammad Maigari, Sani Sharif Usman, Shariff Bilal Abdullahi, Bashir Abdullahi, Abdullahi Ibrahim Uba, Musa Dahiru
Publikováno v:
Heliyon
Heliyon, Vol 5, Iss 8, Pp e02214-(2019)
Heliyon, Vol 5, Iss 8, Pp e02214-(2019)
Background: Iron-deficiency anemia (IDA) or iron deficiency (ID) is by far the most common form of disorder affecting the cognitive development, physical growth and school performance of children in developing countries including Nigeria. Objectives:
Publikováno v:
European Journal of Medicinal Plants. 11:1-7
Publikováno v:
Lasers in Surgery and Medicine. 48:409-415
Background and Objectives Low-level laser therapy (LLLT), is an important application modality for the advancement of wound healing processes. In this study, histological and morphometric analyses have been made to understand and compare effects of h
Autor:
Christina Radicella, Chun Wu, Abdullahi Ibrahim Uba, Siyan Liao, Nicolas Scorese, Haiguang Liu, Carolyn Readmond
Publikováno v:
Life Sciences. 252:117643
Aims Non-peptide ligands of oxytocin receptor (OTR) have promising potentialities as therapeutic agents with improved pharmacological properties. WAY-267,464 is a non-peptide agonist which loses its agonist activity when its resorcinol moiety is meth
Autor:
Kemal Yelekçi, Abdullahi Ibrahim Uba
Publikováno v:
Computational biology and chemistry. 75
Human histone deacetylase 6 (HDAC6) has been shown to play a major role in oncogenic cell transformation via deacetylation of alpha-tubulin making it a viable target of anticancer drug design and development. The crystal structure of HDAC6 catalytic