Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Jia, Nan"'
Autor:
Wen-Biao Wu, Kan Weijuan, Tao Liu, Tingting Jin, Lei Xu, Tao Wang, Liu Jieyu, Kailong Jiang, Yu-qi Xiang, Han‐lin Wang, Ning Song, Jian-Min Yang, Xu Gaoya, Yongzhou Hu, Jia Li, Anhui Gao, Jia-Nan Li, Yubo Zhou, Tong Lexian, Hu Xiaobei, Zhang Mengmeng, Kaixiang Zhang
Publikováno v:
Acta Pharmacol Sin
Checkpoint kinase 1 inhibitors (CHK1i) have shown impressive single-agent efficacy in treatment of certain tumors, as monotherapy or potentiators of chemotherapy in clinical trials, but the sensitive tumor types and downstream effectors to dictate th
Autor:
Yubo Zhou, Zhi-jia Wang, Yu-qi Xiang, Hu Xiaobei, Tiancheng Dong, Wen-Biao Wu, Lei Xu, Kan Weijuan, Jia Li, Hanlin Wang, Bo Feng, Jia-Nan Li, Anhui Gao, Xiaotuan Zhang, Chunmei Xia
Publikováno v:
Acta Pharmacol Sin
Diffuse large B-cell lymphoma (DLBCL) is the most widespread type of non-Hodgkin lymphoma (NHL). As the most aggressive form of the DLBCL, the activated B-cell-like (ABC) subtype is often resistant to standard chemotherapies. Bruton’s tyrosine kina
Autor:
Tian Xing, Zhang Feng, Chao Li, Ya-Ru Yang, Ming-Ming Liu, Xin-Yun Fang, Yuan He, Fang Wang, Xiao-Yan He, Xiao-Guo Suo, Jia-Nan Wang, Juan Jin, Jun Li, Hongmei Zang, Xiao-Ming Meng, Xiang Zhong, Wei-Jian Ni, Yu-Ting Cai, Yu-hang Dong
Publikováno v:
Acta Pharmacol Sin
Stratifin (SFN) is a member of the 14-3-3 family of highly conserved soluble acidic proteins, which regulates a variety of cellular activities such as cell cycle, cell growth and development, cell survival and death, and gene transcription. Acute kid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ff2b02515db5cfe9d3bb466430dfdc
https://europepmc.org/articles/PMC8791945/
https://europepmc.org/articles/PMC8791945/
Autor:
Jia-Nan Ni, Yingying Guo, Guangcui Chu, Dandan Cheng, Gang Bai, Nianwei Chang, Unchol Kim, Min Jiang
Publikováno v:
World Journal of Traditional Chinese Medicine, Vol 5, Iss 1, Pp 1-8 (2019)
Objective: The main objective of the study is to screen the quality markers (Q-markers) for relieving oxidative stress damage and against chronic cerebral ischemia in Shunaoxin pills (SNX). Methods: The benefit effect of SNX was evaluated by a rat ch
Publikováno v:
Journal of Chromatography B. 1092:220-227
Coronary heart disease is a vital cause of morbidity and mortality worldwide, and calcium channel blockers (CCBs) are important drugs that can be used to treat cardiovascular diseases. Suxiao Jiuxin Pill (SX), a traditional Chinese medicine, is widel
Autor:
Zeng Li, Hai-Di Li, Jun Li, Hai-Yong Chen, Juan Jin, Biao Wei, Xiao-Ming Meng, Li Gao, Wei-Feng Wu, Jia-Nan Wang
Publikováno v:
Phytomedicine : international journal of phytotherapy and phytopharmacology. 69
Background 7-Hydroxycoumarin (7-HC), also known as umbelliferon, is commonly found in Chinese herbs (e.g. Eucommiae Cortex, Prunellae Spica, Radix Angelicae Biseratae). Previous laboratory studies have indicated that 7-HC has anti-inflammatory, anti-
Publikováno v:
Phytotherapy Research. 32:1311-1319
Shikonin, a natural naphthoquinone compound derived from the herb Lithospermum erythrorhizon, is widely used for its various pharmacological activities. However, its potential interactions with other medications by inhibiting human carboxylesterases
Publikováno v:
Molecular Medicine Reports. 15:4286-4290
Astemizole has gained attention as an antineoplastic drug that targets important ion channels. The present study aimed to investigate the protective effects of astemizole against hydrogen peroxide (H2O2)‑induced oxidative damage to human umbilical
Autor:
James A. H. Murray, Fabien Melchiore, Natalia Matassova, C. Pedder, Frédéric Colland, Catherine Chang, Levente Ondi, Laura C. A. Galbraith, Pawel Dokurno, Andrew W. Roberts, Chris D. Riffkin, Nolwen Guigal-Stephan, Proszenyák Ágnes, John A. Hickman, Andreas Strasser, Aurélie Studeny, Gaëlle Lysiak-Auvity, András Kotschy, Gemma L. Kelly, Fabienne Gravé, Ghislaine Guasconi, Brandon J. Aubrey, Attila Paczal, Julia Smith, Szlávik Zoltán, Gabor Radics, Brian Lockhart, David C.S. Huang, Maïa Chanrion, Gaëtane Le Toumelin-Braizat, Jia-Nan Gong, Nicolas Cauquil, Szabolcs Sipos, Alan P. Robertson, Giovanna Pomilio, James Edward Paul Davidson, Zoltán B. Szabó, Ana Leticia Maragno, Chris Graham, Marco J Herold, Gábor Blasko, Margs S. Brennan, Anne-Marie Girard, Allan E. Surgenor, Andrew H. Wei, Csékei Márton, Olivier Geneste, Chen I-Jen, Alain Bruno, David J. Segal, Guillaume Lessene, Balázs Bálint, Donia M Moujalled
Publikováno v:
Nature. 538:477-482
Avoidance of apoptosis is critical for the development and sustained growth of tumours. The pro-survival protein myeloid cell leukemia 1 (MCL1) is overexpressed in many cancers, but the development of small molecules targeting this protein that are a
Autor:
Jia-Nan Wang, Qin Yang, Fang Wang, Xue-Qi Liu, Biao Wei, Xin Chen, Xiao-Wei Hu, Ling Jiang, Chao Li, Jun Li, Juan Jin, Taotao Ma, Yong-Gui Wu, Ming-Ming Liu, Yu-Ting Cai, Ju-Tao Yu, Xiao-Ming Meng
Publikováno v:
Clinical science (London, England : 1979). 133(14)
Acute kidney injury (AKI) is a destructive clinical condition induced by multiple insults including ischemic reperfusion, nephrotoxic drugs and sepsis. It is characterized by a sudden decline in renal function, in addition to excessive inflammation,