Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ye Zheng"'
Publikováno v:
Methods
High-throughput genome-wide chromatin conformation capture assay (Hi-C) is routinely used to profile long-range genomic interactions and three-dimensional organization of genomes. A key application of Hi-C is the comparative analysis of genomic inter
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the expression of microRNA (miR)-133a in patients with or without acute myocardial infarction (AMI) following radical surgery for gastric cancer, and to explore its underlying mechanisms. Blood samples were coll
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Nitration of tyrosine at the tenth residue (Tyr10) in amyloid-β (Aβ) has been reported to reduce its aggregation and neurotoxicity in our previous studies. However, the exact mechanism remains unclear. Here, we used Aβ1–42 peptide with different
Autor:
Chun-Ye Zheng, Hong-Feng Liang, Xiao-Dong Luo, Ai-Ping Gu, Qiao-Zhen Su, Jun Cai, Xin-Chun Zhang, Hua-Jun Wang
Publikováno v:
Biochemical and Biophysical Research Communications. 502:269-275
Neuroinflammation plays a critical role in the process of neurodegenerative disorders, during which microglia, the principal resident immune cells in the central nervous system, are activated and produce proinflammatory mediators. Yin-Yang 1 (YY1), a
Autor:
Sunduz Keles, Ye Zheng
Publikováno v:
Nature methods
The ability to simulate high-throughput chromatin conformation (Hi-C) data is foundational for benchmarking Hi-C data analysis methods. Here we present a nonparametric strategy named FreeHi-C to simulate Hi-C data from the interacting genome fragment
Autor:
S. Jeson Sangaralingham, Gerald E. Harders, Shuchong Pan, Ye Zheng, John C. Burnett, Yang Chen, Seethalakshmi R. Iyer, Tomoko Ichiki, Horng H. Chen
Publikováno v:
J Mol Cell Cardiol
The native particulate guanylyl cyclase B receptor (pGC-B) activator, C-type natriuretic peptide (CNP), induces anti-remodeling actions in the heart and kidney through the generation of the second messenger 3', 5' cyclic guanosine monophosphate (cGMP
Autor:
Qiongshi Lu, Kunling Huang, Sushmita Roy, Junha Shin, Daifeng Wang, Yuchang Wu, Zheng Ni, Jing You, Sunduz Keles, Yupei Lin, Ye Zheng, Alireza Fotuhi Siahpirani, Jiawen Chen
Publikováno v:
PLoS Genetics, Vol 17, Iss 2, p e1009309 (2021)
PLoS Genetics
PLoS Genetics
Recent advances in consortium-scale genome-wide association studies (GWAS) have highlighted the involvement of common genetic variants in autism spectrum disorder (ASD), but our understanding of their etiologic roles, especially the interplay with ra
Autor:
Ruiqi Liao, Emery H. Bresnick, Yuannyu Zhang, Jian Xu, Joshua J. Coon, Nobuyuki Tanimura, Matthew R. Dent, Peiman Hematti, Gary M. Wilson, Ye Zheng, Xin Liu, Miao Cao, Judith N. Burstyn, Sunduz Keles
Publikováno v:
Developmental cell. 46(5)
By functioning as an enzyme cofactor, hemoglobin component, and gene regulator, heme is vital for life. One mode of heme-regulated transcription involves amplifying the activity of GATA-1, a key determinant of erythrocyte differentiation. To discover
Autor:
Liang Chen, Wei Lu, Yanling Feng, Ye Zheng, Zhanqing Zhang, Xiaonan Zhang, Weixia Wang, Zhenghong Yuan, Lu Bai
Persistent hepatitis B virus (HBV) infection is established by the formation of an intranuclear pool of covalently closed circular DNA (cccDNA) in the liver. Very little is known about the intrahepatic distribution of HBV cccDNA in infected patients,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d523d308a0f6f8281b36c1f61776af3
https://europepmc.org/articles/PMC4767362/
https://europepmc.org/articles/PMC4767362/
Autor:
Gwen Lomberk, Angela Mathison, Adrienne Grzenda, Jin-San Zhang, Thomas Wesley Allen, Ezequiel Calvo, Navtej S. Buttar, Juan L. Iovanna, Ye Zheng, Franklyn G. Prendergast, Gaurang S. Daftary, Raul Urrutia, Daniel D. Billadeau, R. Gada
Publikováno v:
The Journal of Biological Chemistry
Background: KLF16 is the least characterized family member of recently described metabolic regulators. Results: We extensively characterize mechanisms of DNA binding and chromatin coupling used by KLF16 to regulate metabolic gene expression. Conclusi