Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Pavel Vodicka"'
Publikováno v:
Molecular Aspects of Medicine. 69:73-92
Colorectal carcinogenesis is a multistep process involving the accumulation of genetic alterations over time that ultimately leads to disease progression and metastasis. Binding of transcription factors to gene promoter regions alone cannot explain t
Autor:
Isabel Gaivão, Alena Opattova, Amaya Azqueta, Roger W. L. Godschalk, Peter Møller, Pavel Vodicka, Sabine A. S. Langie, Sona Vodenkova, Maria Dusinska, Andrew Collins
Publikováno v:
Nature Protocols, 15(12), 3844-3878. Nature Publishing Group
Vodenkova, S, Azqueta, A, Collins, A, Dusinska, M, Gaivao, I, Møller, P, Opattova, A, Vodicka, P, Godschalk, R W L & Langie, S A S 2020, ' An optimized comet-based in vitro DNA repair assay to assess base and nucleotide excision repair activity ', Nature Protocols, vol. 15, pp. 3844–3878 . https://doi.org/10.1038/s41596-020-0401-x
Nature Protocols
Vodenkova, S, Azqueta, A, Collins, A, Dusinska, M, Gaivao, I, Møller, P, Opattova, A, Vodicka, P, Godschalk, R W L & Langie, S A S 2020, ' An optimized comet-based in vitro DNA repair assay to assess base and nucleotide excision repair activity ', Nature Protocols, vol. 15, pp. 3844–3878 . https://doi.org/10.1038/s41596-020-0401-x
Nature Protocols
This optimized protocol (including links to instruction videos) describes a comet-based in vitro DNA repair assay that is relatively simple, versatile, and inexpensive, enabling the detection of base and nucleotide excision repair activity. Protein e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::236e3676d540baba829f4f94c0f17895
https://cris.maastrichtuniversity.nl/en/publications/e033f6dc-1d6a-490e-ab22-99c28a0fc192
https://cris.maastrichtuniversity.nl/en/publications/e033f6dc-1d6a-490e-ab22-99c28a0fc192
Autor:
Asta Försti, Alena Kazimirova, Yasmeen Niazi, Per Hoffmann, Hauke Thomsen, Katarina Volkovova, Magdalena Barancokova, Veronika Vymetalkova, Kari Hemminki, Maria Dusinska, Pavel Vodicka, Markus M. Nöthen, Marta Staruchova, Soňa Vodenkova, Ludmila Vodickova, Ludovit Musak, Michal Kroupa, Bozena Smolkova
Publikováno v:
DNA repair. 101
Nonspecific structural chromosomal aberrations (CAs) can be found at around 1% of circulating lymphocytes from healthy individuals but the frequency may be higher after exposure to carcinogenic chemicals or radiation. The frequency of CAs has been me
Autor:
Ludmila Vodickova, Veronika Vymetalkova, Pavel Vodicka, Fabian Caja, Jan Kral, Alessio Naccarati
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5561, p 5561 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The phenotypic effects of single nucleotide polymorphisms (SNPs) in the development of sporadic solid cancers are still scarce. The aim of this review was to summarise and analyse published data on the associations between SNPs in mismatch repair gen
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3260, p 3260 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3260, p 3260 (2020)
Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new cases per year worldwide. CRC outcome is closely related to the respective stage of CRC and is more favorable at less advanced stages. Detection of early colorec
Autor:
Alena Opattova, Veronika Vymetalkova, Michaela Schneiderova, Markéta Urbanová, Kristyna Tomasova, Ludmila Vodickova, Pavol Makovicky, Rudolf Stetina, Klara Kostovcikova, Anna Siskova, Pavel Vodicka, Michal Kroupa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2473, p 2473 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Oxidative stress with subsequent premutagenic oxidative DNA damage has been implicated in colorectal carcinogenesis. The repair of oxidative DNA damage is initiated by lesion-specific DNA glycosylases (hOGG1, NTH1, MUTYH). The direct evidence of the
Autor:
Michael Kundi, Miroslav Mišík, Pavel Vodicka, Georg Wultsch, Armen Nersesyan, Monika Waldherr, Tahereh Setayesh, Ludmila Vodickova, Siegfried Knasmüller
Publikováno v:
Journal of Toxicology and Environmental Health, Part A. 80:651-660
Results of a number of studies indicate that electroplaters have increased cancer risks as a consequence of exposure to genotoxic metals such as chromium (VI) and nickel. These effects may be due to induction of damage of the genetic material which p
Autor:
Marc J. Gunter, Ludmila Vodicka, David J. Hughes, Pavel Vodicka, Elom K. Aglago, Mazda Jenab, Victor Moreno, Neil Murphy
Publikováno v:
Molecular aspects of medicine. 69
Colorectal cancer (CRC) incidence changes with time and by variations in diet and lifestyle, as evidenced historically by migrant studies and recently by extensive epidemiologic evidence. The worldwide heterogeneity in CRC incidence is strongly sugge
Autor:
Guus van Dalum, Veronika Vymetalkova, Antoni Castells, Hege Marie Vedeld, Georg Flügen, Remond J.A. Fijneman, Ellen Heitzer, Emma Tham, Rui P L Neves, Nikolas H. Stoecklein, Saray Duran-Sanchon, Guro Elisabeth Lind, Pavel Vodicka, Meritxell Gironella, Vanesa García-Barberán, María Marcuello
Publikováno v:
Molecular aspects of medicine. 69
New non-invasive approaches that can complement and improve on current strategies for colorectal cancer (CRC) screening and management are urgently needed. A growing number of publications have documented that components of tumors, which are shed int
Autor:
Tomas Buchler, Alessio Naccarati, Michaela Schneiderova, Veronika Veskrnova, Vaclav Liska, Tanja Gumpenberger, Katerina Jiraskova, David J. Hughes, Miroslav Levy, Pavel Vodicka, Sona Vodenkova, Stefanie Brezina, Barbara Pardini, Andrea Gsur, Cornelia Di Gaetano, Veronika Vymetalkova
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 1
International Journal of Molecular Sciences, Vol 20, Iss 1, p 97 (2018)
Volume 20
Issue 1
International Journal of Molecular Sciences, Vol 20, Iss 1, p 97 (2018)
DNA repair processes are involved in both the onset and treatment efficacy of colorectal cancer (CRC). A change of a single nucleotide causing an amino acid substitution in the corresponding protein may alter the efficiency of DNA repair, thus modify