Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Pavel Vodicka"'
Autor:
Ludmila Vodickova, Andrea Cumova, Sivaramakrishna Rachakonda, Pavel Soucek, Rajesh Kumar, Sona Vodenkova, Michal Kroupa, Andrea Rossnerova, Kari Hemminki, Vaclav Liska, Veronika Vymetalkova, Kristyna Tomasova, Pavel Vodicka
Publikováno v:
Mutagenesis. 35:491-497
Disruption of telomere length (TL) homeostasis in peripheral blood lymphocytes has been previously assessed as a potential biomarker of breast cancer (BC) risk. The present study addressed the relationship between lymphocyte TL (LTL), prognosis and c
Autor:
Ludmila Vodickova, Veronika Vymetalkova, Miguel Inacio da Silva Filho, Asta Försti, Christoph Frank, Katerina Jiraskova, Calogerina Catalano, Alessio Naccarati, Vaclav Liska, Miroslav Levy, Pavel Vodicka, Shun Lu, Alexander N.R. Weber, Kari Hemminki, Ondrej Vycital
Publikováno v:
Cancer Medicine, Vol 9, Iss 4, Pp 1473-1484 (2020)
Cancer Medicine
Cancer Medicine
Objective The TLR3/cGAS‐STING‐IFN signaling has recently been reported to be disturbed in colorectal cancer due to deregulated expression of the genes involved. Our study aimed to investigate the influence of potential regulatory variants in thes
Autor:
Jirong Long, Anna H. Wu, Min-Ho Shin, Tabitha A. Harrison, Kenneth Offit, Ulrike Peters, Yoon-Ok Ahn, Fränzel J.B. Van Duijnhoven, Jochen Hampe, Qiuyin Cai, Stephanie J. Weinstein, Annika Lindblom, Zhi Zhong Pan, Keum Ji Jung, Chizu Tanikawa, Wanqing Wen, Andrew T. Chan, Wei Hua Jia, Yu-Tang Gao, Isao Oze, Keitaro Matsuo, Zefang Ren, Sun-Seog Kweon, Paul D.P. Pharoah, Victor Moreno, Pavel Vodicka, Yong-Bing Xiang, Jeroen R. Huyghe, Aesun Shin, Dong Hyun Kim, Sun Ha Jee, Koichi Matsuda, Jae Hwan Oh, Andrea Gsur, Yi Xin Zeng, Yingchang Lu, Nan Wang, Jiajun Shi, Wei Zheng, Bethany Van Guelpen, Loic Le Marchand, Li Li, Honglan Li, Jeongseon Kim, Alicja Wolk, Xingyi Guo, Polly A. Newcomb, Yoichiro Kamatani, Li Hsu, Jing Gao, Xiao-Ou Shu, Bingshan Li
Publikováno v:
Cancer Epidemiol Biomarkers Prev
Cancer Epidemiology Biomarkers & Prevention 29 (2020) 2
Dipòsit Digital de la UB
Universidad de Barcelona
Cancer Epidemiology Biomarkers & Prevention, 29(2), 477-486
Cancer Epidemiology Biomarkers & Prevention 29 (2020) 2
Dipòsit Digital de la UB
Universidad de Barcelona
Cancer Epidemiology Biomarkers & Prevention, 29(2), 477-486
Background: Risk variants identified so far for colorectal cancer explain only a small proportion of familial risk of this cancer, particularly in Asians. Methods: We performed a genome-wide association study (GWAS) of colorectal cancer in East Asian
Autor:
Simona Susova, Linda Bartu, Jan Kral, Pavel Soucek, Rajesh Kumar, Ludmila Vodickova, Miroslav Levy, Tomas Buchler, Fabio Rosa, Petra Bendova, Veronika Vymetalkova, Pavel Vodicka, David J. Hughes, Alessio Naccarati, Barbara Pardini
Publikováno v:
Mutagenesis. 35:273-281
The chemotherapeutic efficacy in colorectal cancer (CRC) is limited due to the inter-individual variability in drug response and the development of tumour resistance. ATP-binding cassette (ABC) transporters are crucial in the development of resistanc
Autor:
Alicja Wolk, Edward Giovannucci, Li Li, Polly A. Newcomb, Kenneth Offit, Clemens Schafmayer, Vicente Martín, Sergi Castellví-Bel, Daniel D. Buchanan, Mingyang Song, Qianchuan He, Martha L. Slattery, Volker Arndt, Anna H. Wu, Amit Joshi, David A. Drew, D. Timothy Bishop, Annika Lindblom, Temitope O. Keku, Jochen Hampe, Ozan Dikilitas, Douglas A. Corley, John B. Harley, Hakon Hakonarson, Steven Gallinger, Noralane M. Lindor, Ian B. Stanaway, Jeffrey K. Lee, Sonja I. Berndt, Veronika Vymetalkova, Syed H.E. Zaidi, Jessica Minnier, Daniel J. Schaid, Ludmila Vodickova, John D. Potter, Heather Hampel, Christopher I. Li, Frank D. Mentch, Wei-Qi Wei, Cornelia M. Ulrich, Marc J. Gunter, Robert E. Schoen, Catherine M. Tangen, Victor Moreno, Shuji Ogino, Tabitha A. Harrison, Albert de la Chapelle, Pavel Vodicka, Andrew T. Chan, Keith R. Curtis, Elisabeth A. Rosenthal, Jenny Chang-Claude, David C. Muller, Paul D.P. Pharoah, Roger L. Milne, David Duggan, Eric B. Larson, David R. Crosslin, Andrea Gsur, Stéphane Bézieau, Graham G. Giles, Robert J. MacInnis, Bahram Namjou, Christopher H. Dampier, Gail P. Jarvik, Andrea N. Burnett-Hartman, Richard B. Hayes, Fränzel J.B. Van Duijnhoven, Wendy K. Chung, Michael Hoffmeister, Mark A. Jenkins, Mathieu Lemire, Thomas J. Hudson, Elizabeth A. Platz, Neil Murphy, Graham Casey, Michael O. Woods, Aung Ko Win, Flora Qu, Li Hsu, Emily White, Peter T. Campbell, Lori C. Sakoda, Jane C. Figueiredo, Minta Thomas, Jeroen R. Huyghe, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Corinne E. Joshu, Yu Ru Su, Ulrike Peters, Stephen B. Gruber, Demetrius Albanes, Stephen N. Thibodeau, Antoni Castells, Hermann Brenner
Publikováno v:
Am J Hum Genet
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying individuals at low and high risk of developing CRC, as they can then be offered targeted screening and interventions to address their risks of developing disease (if
Autor:
Christopher I. Amos, Harvey A. Risch, Alison P. Klein, Yau-Hua Yu, Rachael Z. Stolzenberg-Solomon, Pavel Vodicka, Dominique S. Michaud, James D. Beck, Laura Corlin, Elizabeth A. Platz, Mengyuan Ruan, Konstantinos K. Tsilidis, Emmanouil Bouras, Pai K Rish, Lori C. Sakoda
Publikováno v:
JNCI Cancer Spectrum
Corlin, L, Ruan, M, Tsilidis, K, Bouras, E, Yu, Y-H, Stolzenberg-Solomo, R, Klein, A P, Risch, H A, Amos, C I, Sakoda, L C, Vodicka, P, Rish, P K, Beck, J, Platz, E A & Michaud, D S 2021, ' Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer ', Journal of the National Cancer Institute, vol. 5, no. 3, pkab037 . https://doi.org/10.1093/jncics/pkab037
Corlin, L, Ruan, M, Tsilidis, K, Bouras, E, Yu, Y-H, Stolzenberg-Solomo, R, Klein, A P, Risch, H A, Amos, C I, Sakoda, L C, Vodicka, P, Rish, P K, Beck, J, Platz, E A & Michaud, D S 2021, ' Two-Sample Mendelian Randomization Analysis of Associations Between Periodontal Disease and Risk of Cancer ', Journal of the National Cancer Institute, vol. 5, no. 3, pkab037 . https://doi.org/10.1093/jncics/pkab037
Background Observational studies indicate that periodontal disease may increase the risk of colorectal, lung, and pancreatic cancers. Using a 2-sample Mendelian randomization (MR) analysis, we assessed whether a genetic predisposition index for perio
Autor:
Verena Katzke, Rita T. Lawlor, Ugo Boggi, Paola Fogar, Livia Archibugi, George Theodoropoulos, Beatrice Mohelnikova-Duchonova, C. E. Radu, Giulia Martina Cavestro, Christos Dervenis, Francesca Federici, Federico Canzian, Jakob R. Izbicki, Claudio Pasquali, Aldo Scarpa, Valerio Pazienza, Péter Hegyi, Renata Talar-Wojnarowska, Frank Bergmann, Thomas Pausch, Stefano Landi, Maurizio Cantore, Stig E. Bojesen, Theron Johnson, Oliver Strobel, Ewa Małecka-Panas, Thilo Hackert, Angelo Andriulli, Audrius Ivanauskas, Benny V. Jensen, J. Kaiser, Daniele Campa, Andrea Mambrini, Orazio Palmieri, Gabriele Capurso, Ludmila Vodickova, Maria Gazouli, Evaristo Maiello, Roberto Salvia, Elżbieta Iskierka-Jażdżewska, Christine Tjaden, Rudolph Kaaks, M. Di Leo, Anna Caterina Milanetto, Pavel Soucek, Daniela Basso, Julia S. Johansen, H Brenner, Raffaele Pezzilli, Katarina Cuk, Ofure Obazee, Cosimo Sperti, Pavel Vodicka, Juozas Kupcinskas, Kai Uwe Saum, Yogesh K. Vashist, G. Delle Fave, Andrea Szentesi, Cristian Gheorghe, Radmila Lemstrová, Inna Chen
Publikováno v:
International Journal of Cancer. 145:686-693
Rare truncating BRCA2 K3326X (rs11571833) and pathogenic CHEK2 I157T (rs17879961) variants have previously been implicated in familial pancreatic ductal adenocarcinoma (PDAC), but not in sporadic cases. The effect of both mutations in important DNA r
Autor:
Charles M. Connolly, Deborah A. Nickerson, Jian Gong, Sébastien Küry, Barbara Pardini, Brent W. Zanke, Andrea Gsur, Jochen Hampe, Coral Arnau-Collell, M. Henar Alonso, Elio Riboli, Annika Lindblom, Ulrike Peters, Gad Rennert, Tabitha A. Harrison, Lori C. Sakoda, Caroline McNeil, Flavio Lejbkowicz, Hyun Min Kang, David J. Hunter, Martha L. Slattery, Miguel Rodríguez-Barranco, Christina Bamia, Satu Männistö, Timothy J. Key, W. James Gauderman, Gonçalo R. Abecasis, Sanford D. Markowitz, Laurence N. Kolonel, Mark A. Jenkins, Yi Lin, Robin Myte, Hedy S. Rennert, Neil Murphy, Antonia Trichopoulou, Christopher I. Li, Ross L. Prentice, Sai Chen, Stephanie J. Weinstein, Kristin E. Anderson, Hua Ling, Mitul Shah, Philipp Hofer, Wen Yi Huang, Sergi Castellví-Bel, Susanna C. Larsson, Maria Dolores Chirlaque, Wei Zheng, Stephanie L. Schmit, Cecelia A. Laurie, Soo-Chin Lee, David Forman, Andrea N. Burnett-Hartman, Giovanna Masala, Sarah C. Nelson, Michael O. Woods, Charles Kooperberg, Qing Zhang, Sonja I. Berndt, Christopher S. Carlson, Katja Butterbach, Hyeong Rok Kim, Rebecca D. Jackson, David Van Den Berg, Michael C. Bassik, Amanda J. Cross, Sushma S. Thomas, Clemens Schafmayer, Anna H. Wu, Douglas F. Easton, Robert W. Haile, Ludmila Vodickova, Graham G. Giles, Yu Ru Su, Jenny Chang-Claude, Lorena Moreno, Peter C. Scacheri, Stefanie Brezina, Min-Ho Shin, Steven Gallinger, Bethany Van Guelpen, Daniel D. Buchanan, Roger L. Milne, Stephen J. Chanock, Tin Louie, Tameka Shelford, Emily White, Kala Visvanathan, Loic Le Marchand, Veronika Vymetalkova, Roxann G. Ingersoll, Temitope O. Keku, Stephanie A. Bien, Fredrick R. Schumacher, Wan-Ling Hsu, Amanda E. Toland, John S. Grove, Noralane M. Lindor, Faye Elliott, Leon Raskin, Heather Hampel, Joshua D. Smith, Vicente Martín, David V. Conti, Sjoerd G. Elias, Henk J. van Kranen, Manish Gala, Daniela Seminara, Syed H.E. Zaidi, Suzanne M. Leal, Tilman Kühn, Korbinian Weigl, Marc J. Gunter, Cornelia M. Ulrich, Peyton Greenside, Victor Moreno, John D. Potter, Michael Hoffmeister, Eric J. Jacobs, Catherine M. Tangen, Jihyoun Jeon, Fränzel J.B. Van Duijnhoven, Andrew T. Chan, Stephen B. Gruber, John A. Baron, Alicja Wolk, Edith J. M. Feskens, Demetrius Albanes, Amit Joshi, Bette J. Caan, Polly A. Newcomb, Stéphane Bézieau, Elizabeth M. Gillanders, Anshul Kundaje, Elizabeth A. Platz, Michael Wainberg, Sun-Seog Kweon, C. Roland Wolf, Gemma Ibáñez-Sanz, Shuji Ogino, Emiko Kobayashi, Richard B. Hayes, Patrick S. Parfrey, Katarina Cuk, Stephen N. Thibodeau, Kenneth Offit, David Duggan, Sophia Harlid, Pavel Vodicka, Juergen Boehm, Christa Stegmaier, Jeroen R. Huyghe, Joseph Vijai, Sang-Hee Cho, Elizabeth W. Pugh, Rachel Pearlman, Alessio Naccarati, Marilena Melas, Graham Casey, Jane Romm, Stephan Buch, Phyllis J. Goodman, Albert de la Chapelle, John L. Hopper, Zsofia K. Stadler, Corinne E. Joshu, Liesel M. FitzGerald, Wolfgang Lieb, Aung Ko Win, Keith R. Curtis, Hermann Brenner, Christopher K. Edlund, Li Hsu, Conghui Qu, Peter T. Campbell, Robert E. Schoen, Heiner Boeing, D. Timothy Bishop, Kimberly F. Doheny, Sabina Sieri, Barbara L. Banbury, Mathieu Lemire, Jane C. Figueiredo, Gregory Idos, Katerina Shulman, Thomas J. Hudson, Melissa C. Southey, Duncan C. Thomas, Paul D.P. Pharoah, Mila Pinchev, Vittorio Perduca, Rocky Fischer, Volker Arndt, William M. Grady, Nasa Sinnott-Armstrong, N. Charlotte Onland-Moret, David M. Levine, Li Li, Dallas R. English
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Nature genetics
Nature Genetics, 51, 76-87
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩
Nature Genetics, 51(1), 76. Nature Publishing Group
Nature Genetics 51 (2018)
Universidad de Barcelona
Nature genetics
Nature Genetics, 51, 76-87
Nature Genetics
Nature Genetics, Nature Publishing Group, 2019, 51 (1), pp.76-87. ⟨10.1038/s41588-018-0286-6⟩
Nature Genetics, 51(1), 76. Nature Publishing Group
Nature Genetics 51 (2018)
To further dissect the genetic architecture of colorectal cancer (CRC), we performed whole-genome sequencing of 1,439 cases and 720 controls, imputed discovered sequence variants and Haplotype Reference Consortium panel variants into genome-wide asso
Autor:
Rudolf Kaaks, Thilo Hackert, Federico Canzian, Livia Archibugi, H. Bas Bueno-de-Mesquita, Angelo Andriulli, Juozas Kupcinskas, Kai Uwe Saum, Yogesh K. Vashist, Andrea Mambrini, Kay-Tee Khaw, Andrea Szentesi, Rita T. Lawlor, Laimas Virginijus Jonaitis, Domenica Gioffreda, Raffaele Pezzilli, Katarina Cuk, Daniela Basso, Ludmila Vodickova, Claudio Pasquali, Pavel Vodicka, Oliver Strobel, Martin Lovecek, Péter Hegyi, Chiara Valsuani, Krzysztof Jamroziak, Gabriele Capurso, Renata Talar-Wojnarowska, Martina Matarazzi, Jakob R. Izbicki, Niccola Funel, Hanneke W. M. van Laarhoven, Pavel Soucek, Daniele Campa, Beatrice Mohelnikova-Duchonova, Francesca Federici, Hermann Brenner, Franco Bambi, Anna Katharina König, Carlo Federico Zambon, Verena Katzke, Maarten F. Bijlsma, William Greenhalf, Francesca Tavano, Felice Pirozzi, Gianfranco Delle Fave, Ofure Obazee, Cosimo Sperti, Jörg Kaiser, Giulia Martina Cavestro, Timothy J. Key, Stefano Landi
Publikováno v:
International Journal of Cancer. 144:1275-1283
Telomere deregulation is a hallmark of cancer. Telomere length measured in lymphocytes (LTL) has been shown to be a risk marker for several cancers. For pancreatic ductal adenocarcinoma (PDAC) consensus is lacking whether risk is associated with long
Autor:
Alena Kazimirova, Magdalena Barancokova, Sona Vodenkova, Marta Staruchova, Markus M. Nöthen, Maria Dusinska, Asta Försti, Ludovit Musak, Ludmila Vodickova, Per Hoffmann, Yasmeen Niazi, Kari Hemminki, Katarina Volkovova, Pavel Vodicka, Hauke Thomsen, Michal Kroupa, Bozena Smolkova, Veronika Vymetalkova
Publikováno v:
Environmental and Molecular Mutagenesis. 60:17-28
Chromosomal aberrations (CAs) in human peripheral blood lymphocytes (PBL) measured with the conventional cytogenetic assay have been used for human biomonitoring of genotoxic exposure for decades. CA frequency in peripheral blood is a marker of cance