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Autor:
Zay Htet, Mahzuz Karim
Publikováno v:
Journal of the Royal Society of Medicine. 114(7)
Recent years have seen a paradigm shift in the management of patients with diabetes mellitus. Rather than good glycaemic control being the sole primary aim, the therapeutic focus has broadened to consider potential additional cardiovascular and renal
Autor:
Teena Mohan, Larisa V. Gubareva
Publikováno v:
Cold Spring Harbor perspectives in medicine. 12(1)
The neuraminidase (NA) of influenza A and B viruses plays a distinct role in viral replication and has a highly conserved catalytic site. Numerous sialic (neuraminic) acid analogs that competitively bind to the NA active site and potently inhibit enz
Autor:
Hannah Dykes, Andrea Sikora Newsome, Timothy W Jones, Susan E. Smith, Christy Forehand, Ashley Taylor
Publikováno v:
J Pharm Pract
Background: The optimal vasopressor management for septic patients with left ventricular (LV) dysfunction has not been well established, and current evidence is conflicting regarding the optimal vasopressor discontinuation order. Objective: The objec
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
Inhaled antibiotics are commonly used to treat persistent airway infection with Pseudomonas aeruginosa that contributes to lung damage in people with cystic fibrosis. Current guidelines recommend inhaled tobramycin for individuals with cystic fibrosi
Autor:
J. Grant Thomson, Kitae E Park, Adnan Prsic, Omar Allam, Alexandre Prassinos, Alexander S. Chiu, Connor J. Peck, Martin J. Carney
Publikováno v:
Hand (New York, N.Y.). 17(6)
Background: Social and demographic factors may influence patient treatment by physicians. This study analyzes the influence of patient sociodemographics on prescription practices among hand surgeons. Methods: We performed a retrospective analysis of
Autor:
Alan H. Daniels, Benjamin H. Shapiro, Joseph A. Gil, Kalpit N. Shah, Peter James, Edward Akelman, Daniel B.C. Reid, Jack H. Ruddell
Publikováno v:
Hand (New York, N.Y.). 17(6)
Background: The Rhode Island State Legislature passed the Uniform Controlled Substances Act in 2016 to limit opioid prescriptions. We aimed to objectively evaluate its effect on opioid prescribing for hand surgery patients and also identify risk fact
Autor:
Armen Voskerijian, Nura Gouda, Mark L. Wang, Michael Rivlin, Pedro K. Beredjiklian, Julian Zangrilli
Publikováno v:
Hand (New York, N.Y.). 17(6)
Background Orthopedic procedures concerning the upper extremity commonly use a brachial plexus nerve block to achieve postoperative analgesia. The addition of dexamethasone to peripheral nerve blocks has been shown to significantly prolong its effect
Publikováno v:
Journal of the Royal Society of Medicine. 113(11)
Tamoxifen exposure is a recognised risk for primary endometrial cancer. This case serves as a reminder to meticulously check the past medical history and inform patients of the risk-benefit of treatment as part of a shared-decision making process.
Publikováno v:
Journal of the American Academy of Dermatology. 88:1338-1344
Background Neutrophilic dermatosis of the dorsal hands is an uncommon localised variant of Sweet syndrome first described in 1995. It is characterised by tender erythematous plaques, pustules and bullae on the dorsa of the hands. Literature Review A
Publikováno v:
Neurología. 38:256-261
INTRODUCTION Advances in the treatment of myasthenia gravis (MG) have improved quality of life and prognosis for the majority of patients. However, 10%-20% of patients present refractory MG, with frequent relapses and significant functional limitatio