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Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 3, p e0193853 (2018)
PLoS ONE, Vol 13, Iss 3, p e0193853 (2018)
17β-estradiol treatment has shown benefit against schizophrenia symptoms, however longterm use may be associated with negative side-effects. Selective estrogen receptor modulators, such as raloxifene and tamoxifen, have been proposed as suitable alt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::011797b2121308140f7e5e9e0a964b89
Publikováno v:
Bulletin of the National Research Centre, Vol 45, Iss 1, Pp 1-15 (2021)
Background Hepatitis C virus (HCV) is a global medical condition that causes several life-threatening chronic diseases in the liver. The conventional interferon-free treatment regimens are currently in use by a blend of direct-acting antiviral agents
Autor:
Raj Raghupathy, Sanjana Rajgopal
Publikováno v:
Annals of the National Academy of Medical Sciences (India), Vol 57, Iss 01, Pp 08-15 (2021)
Pregnancy is not nearly as successful as laypersons might assume, challenged as it is by several complications such as threatened abortion, spontaneous miscarriage, preeclampsia, and preterm delivery, among others. The maternal immune system has been
Publikováno v:
Bulletin of the National Research Centre, Vol 45, Iss 1, Pp 1-7 (2021)
Background This study was aimed to determine the prevalence of qnr genes among fluoroquinolone-resistant Escherichia coli (FREC) isolates from Nigeria. Antimicrobial susceptibility testing was performed by disc diffusion technique. Polymerase chain r
Autor:
Katja Anttila, Andrew P. Stubbs, Rob C. I. Wüst, Yanti Octavia, Lau Blonden, Vincent J. de Beer, Bas M. van Dalen, Daphne Merkus, Youri Hoogstrate, Ilkka Heinonen, Richard W. B. van Duin, Milla Alkio, Jolanda van der Velden, Oana Sorop, Dirk J. Duncker, Jens van de Wouw
Publikováno v:
Scientific Reports, 10(1):13173, 1-14. Nature Publishing Group
Scientific Reports, 10(1):13173. Nature Publishing Group
Heinonen, I, Sorop, O, van Dalen, B M, Wüst, R C I, van de Wouw, J, de Beer, V J, Octavia, Y, van Duin, R W B, Hoogstrate, Y, Blonden, L, Alkio, M, Anttila, K, Stubbs, A, van der Velden, J, Merkus, D & Duncker, D J 2020, ' Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement ', Scientific Reports, vol. 10, no. 1, 13173, pp. 1-14 . https://doi.org/10.1038/s41598-020-68637-4
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Heinonen, I, Sorop, O, van Dalen, B M, Wüst, R C I, van de Wouw, J, de Beer, V J, Octavia, Y, van Duin, R W B, Hoogstrate, Y, Blonden, L, Alkio, M, Anttila, K, Stubbs, A, van der Velden, J, Merkus, D & Duncker, D J 2020, ' Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement ', Scientific Reports, vol. 10, no. 1, 13173 . https://doi.org/10.1038/s41598-020-68637-4
Scientific Reports, 10(1):13173. Nature Publishing Group
Heinonen, I, Sorop, O, van Dalen, B M, Wüst, R C I, van de Wouw, J, de Beer, V J, Octavia, Y, van Duin, R W B, Hoogstrate, Y, Blonden, L, Alkio, M, Anttila, K, Stubbs, A, van der Velden, J, Merkus, D & Duncker, D J 2020, ' Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement ', Scientific Reports, vol. 10, no. 1, 13173, pp. 1-14 . https://doi.org/10.1038/s41598-020-68637-4
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Heinonen, I, Sorop, O, van Dalen, B M, Wüst, R C I, van de Wouw, J, de Beer, V J, Octavia, Y, van Duin, R W B, Hoogstrate, Y, Blonden, L, Alkio, M, Anttila, K, Stubbs, A, van der Velden, J, Merkus, D & Duncker, D J 2020, ' Cellular, mitochondrial and molecular alterations associate with early left ventricular diastolic dysfunction in a porcine model of diabetic metabolic derangement ', Scientific Reports, vol. 10, no. 1, 13173 . https://doi.org/10.1038/s41598-020-68637-4
The prevalence of diabetic metabolic derangement (DMetD) has increased dramatically over the last decades. Although there is increasing evidence that DMetD is associated with cardiac dysfunction, the early DMetD-induced myocardial alterations remain
Autor:
Akira Fukuya, Yasuo Takahashi, Masahiro Hirakawa, Yasushi Sato, Hiroshi Miyamoto, Kyoko Hamaguchi, Tetsuji Takayama, Naoki Muguruma, Tamotsu Sagawa, Koshi Fujikawa, Koichi Okamoto
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
The primary tumour location is an important prognostic factor for previously untreated metastatic colorectal cancer (mCRC). However, the predictive efficacies of primary tumour location, early tumour shrinkage (ETS), and depth of response (DpR) on mC
Autor:
Donghwan Kim, Shogo Takahashi, Jessica A. Bonzo, Kritika Karri, Chad Brocker, Moshe Levi, Tisha Melia, Thomas J. Velenosi, Daisuke Aibara, Frank J. Gonzalez, David J. Waxman
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications
Nature Communications
Exploring the molecular mechanisms that prevent inflammation during caloric restriction may yield promising therapeutic targets. During fasting, activation of the nuclear receptor peroxisome proliferator-activated receptor α (PPARα) promotes the ut
Autor:
Kaiqi Kang, Jianguo Li, Zefeng Gao, Jingjing Jia, XianJun Liu, Chunyan Hao, Weiwei Guo, Zhijiang Rong
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Propionate has been reported to exert antidepressant effects, but high-dose propionate may induce autism-like symptoms in experimental animals through induction of dysbiosis of neurotransmitters. The bi-directional effects of propionate seem to be do
Autor:
Anna Ianza, Monica Ramello, Enrico Mini, Giandomenico Roviello, Alberto D'Angelo, Martina Catalano, Raffaele Conca, Lorenzo Dreoni, Roberto Petrioli, Stefania Nobili, Silvia Gasperoni, Michele Aieta
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Scientific Reports
Scientific Reports
Neutropenia is a common side effect associated with nab-paclitaxel gemcitabine (Nab-Gem) therapy. We retrospectively investigated the association between neutropenia induced by first-line Nab-Gem and survival in metastatic pancreatic carcinoma patien
Autor:
Chengwei Tang, Xiao Ma, Ming Zhou, Chong Zhao, Libin Huang, Jinhang Gao, Huan Tong, Rui Liu, Qinghua Tan, Zhe Feng, Jinsun Jiang, Ling Liu, Ming-Guang Zhang, Zhiyin Huang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-10 (2020)
Scientific Reports
Scientific Reports
Duodenal dysbiosis may be potential infection risks in patients with severe acute pancreatitis (SAP). Acid-suppression drugs (ACDs) are widely used in SAP patients in Asian countries. However, the impact of ACDs on duodenal microbiota during the earl