Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jiaxin Niu"'
Autor:
Adil Daud, Mohammed M. Milhem, Riyue Bao, Yousef Zakharia, Jiaxin Niu, Geoffrey T. Gibney, David Mauro, Kim Margolin, Arthur M. Krieg, Antoni Ribas, Heather Kelley, Anthony J. Olszanski, Elizabeth I. Buchbinder, Jason J. Luke, Diwakar Davar, Theresa Medina, John M. Kirkwood, Aaron H. Morris, Katie M. Campbell, Montaser Shaheen, Inderjit Mehmi, James E. Wooldridge, George J. Weiner, Takami Sato
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Background Therapeutic options are limited for patients with advanced melanoma that is refractory to PD-1 blockade. This study was performed in this patient population to assess the safety and antitumor activity of CMP-001, a CpG-A TLR9 agonist packa
Autor:
Adil Daud, Montaser Shaheen, David J. Mauro, Geoffrey T. Gibney, Interjit Mehmi, Antoni Ribas, Kim Margolin, Mohammed M. Milhem, Arthur M. Krieg, Takami Sato, Elizabeth I. Buchbinder, Yousef Zakharia, John M. Kirkwood, Diwakar Davar, Aaron Morris, Katie M. Campbell, Riyue Bao, Theresa Medina, George J. Weiner, Jiaxin Niu, Anthony J. Olszanski, Jason Luke
Publikováno v:
Oral Presentations.
Background Intratumoral (IT) injection of CMP-001, a CpG-A TLR9 agonist packaged within a virus-like particle, is designed to activate tumor-associated plasmacytoid dendritic cells, inducing an interferon-rich tumor microenvironment and anti-tumor CD
Autor:
Rene Gonzales, Jiaxin Niu, Jason J. Luke, Theresa Medina, Aaron H. Morris, Antoni Ribas, David J. Mauro, John M. Kirkwood, Kim Margolin, Elizabeth I. Buchbinder, Mohammed M. Milhem, Arthur M. Krieg, Inderjit Mehmi, Ryan M. Weight, Montaser Shaheen
Publikováno v:
Cancer Research. 78:CT144-CT144
Background: CMP-001 comprises a CpG-A oligodeoxynucleotide packaged within a virus-like particle. It is designed to activate tumor-associated plasmacytoid dendritic cells via TLR9 inducing an interferon-rich tumor microenvironment and anti-tumor CD8+