Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Wenyu Lin"'
Autor:
Yongfu Huang, Esperance A. Schaefer, Yongju Zhao, Ming-Lung Yu, Haoju Wang, Zeng Tu, Chuanlong Zhu, Anna Lidofsky, Xiaoqiong Duan, Zhiwen Xu, Raymond T. Chung, Dachuan Cai, Shadi Salloum, Shilin Li, Limin Chen, Jian Hong, Wenyu Lin, Jacinta A. Holmes, Wenting Li, Sae Hwan Lee, Xiao Liu
Publikováno v:
Hepatology. 69:1004-1019
Long noncoding RNAs (lncRNAs) play a critical role in the regulation of many important cellular processes. However, the mechanisms by which lncRNAs regulate viral infection and host immune responses are not well understood. We sought to explore lncRN
Autor:
Xiaoqiong Duan, Yujia Li, He Xie, Chunhui Yang, Shilin Li, Kai Ren, Haiyan Ye, Min Xu, Xinzhong Liao, Shuang Li, Limin Chen, Wenyu Lin
Publikováno v:
Viruses
Volume 12
Issue 4
Viruses, Vol 12, Iss 418, p 418 (2020)
Volume 12
Issue 4
Viruses, Vol 12, Iss 418, p 418 (2020)
Background: 2&rsquo
5&rsquo
oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore
5&rsquo
oligoadenylate synthetase 2 (OAS2) has been known as an antiviral interferon-stimulated gene (ISG). However, the role of OAS2 on Zika virus (ZIKV) replication is still unknown. In this study, we sought to explore
Autor:
Nadia Alatrakchi, Jian Hong, Wenyu Lin, Jacinta A. Holmes, Cynthia Brisac, Stephane Chevaliez, Raymond T. Chung, Annie J. Kruger, Charlie Carlton-Smith, Esperance A. Schaefer, Victor Yang, Shadi Salloum
Publikováno v:
Journal of Hepatology. 65:972-979
Background & Aims Type I interferons (IFN) provide the first line of defense against invading pathogens but its mechanism of action is still not well understood. Using unbiased genome-wide siRNA screens, we recently identified IQ-motif containing GTP
Autor:
Xu Shi, Robert E. Gerszten, Wenyu Lin, Anthony Anselmo, Tetsurou Satoh, Raymond T. Chung, Megha Basavappa, Henry Pratt, Takuya Tomaru, Satoshi Yoshino, Dahlene N. Fusco, Stephen Kandilas, D. Alex Cronkite, Ruslan I. Sadreyev, Kate L. Jeffrey, Scarlett Se Yun Cheon, John F. O'Sullivan, Clarence Yapp
Publikováno v:
Frontiers in Microbiology
Flaviviral infections including dengue virus are an increasing clinical problem worldwide. Dengue infection triggers host production of the type 1 IFN, IFN alpha, one of the strongest and broadest acting antivirals known. However, dengue virus subver
Autor:
Yaakov Nahmias, Patrick Balaguer, Danny Kitsberg, Wenyu Lin, Raymond T. Chung, Martin L. Yarmush, Pazit Y. Cohen, Stephen J. Polyak, Jonathan Goldwasser
Publikováno v:
Journal of hepatology. 55(5)
Background & Aims Hepatitis C virus (HCV) infection affects 3% of the world population and is the leading cause of chronic liver disease worldwide. Current standard of care is effective in only 50% of the patients, poorly tolerated, and associated wi