Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Wenyu Lin"'
Autor:
Rongbin Yu, Jacinta A Holmes, Chuanwu Zhu, Wenyu Lin, Sheng Yang, Zhijun Ge, Yan Wang, Raymond T. Chung, Peng Huang, Andre J Jeyarajan, Ming Yue, Xueshan Xia
Publikováno v:
Liver Int
Background & aims The risk for hepatitis C virus (HCV) recurrence persists after HCV eradication with direct-acting antivirals (DAAs), particularly in patients with ongoing high-risk behaviours. Our aim was to assess the risk of HCV recurrence (late
Autor:
Nadia Alatrakchi, Jian Hong, Wenyu Lin, Jacinta A. Holmes, Cynthia Brisac, Stephane Chevaliez, Raymond T. Chung, Annie J. Kruger, Charlie Carlton-Smith, Esperance A. Schaefer, Victor Yang, Shadi Salloum
Publikováno v:
Journal of Hepatology. 65:972-979
Background & Aims Type I interferons (IFN) provide the first line of defense against invading pathogens but its mechanism of action is still not well understood. Using unbiased genome-wide siRNA screens, we recently identified IQ-motif containing GTP
Autor:
Tuo Shao, Dong Chen, Batul Kaj, Xiao Liu, Annie J. Kruger, Qiuju Sheng, Wenting Li, Xiaoqiong Duan, Wenyu Lin, Min Xu, Shuang Li, Jacinta A. Holmes, Limin Chen, Raymond T. Chung, Yujia Li, Haiyan Ye, Chunhui Yang, Shilin Li, Zhimeng Cheng, Esperance A. Schaefer, Xinzhong Liao
Publikováno v:
Cells
Volume 8
Issue 4
Cells, Vol 8, Iss 4, p 338 (2019)
Volume 8
Issue 4
Cells, Vol 8, Iss 4, p 338 (2019)
We previously identified that miR-130a downregulates HCV replication through two independent pathways: restoration of host immune responses and regulation of pyruvate metabolism. In this study, we further sought to explore host antiviral target genes
Autor:
Wenting Li, Wenyu Lin, Zeng Tu, Baihai Jiao, Esperance A. Schaefer, Xiao Liu, Limin Chen, Xiaoqiong Duan, Dachuan Cai, Shadi Salloum, Shilin Li, Chunhui Yang, Dahlene N. Fusco, Jacinta A. Holmes, Raymond T. Chung, Yujia Li
Publikováno v:
Journal of Virology
Hepatitis C virus (HCV) infection has been shown to regulate microRNA 130a (miR-130a) in patient biopsy specimens and in cultured cells. We sought to identify miR-130a target genes and to explore the mechanisms by which miR-130a regulates HCV and hep
Autor:
Andrew Yang, Raymond T. Chung, Esperance A. Schaefer, Cynthia Brisac, Lee F. Peng, Christina Mark, Daniel L. Motola, Dahlene N. Fusco, Clary B. Clish, Shadi Salloum, Amy Deik, Wenyu Lin, James Meixiong
Publikováno v:
World Journal of Gastroenterology
AIM To characterize the role of apolipoprotein B100 (apoB100) in hepatitis C viral (HCV) infection. METHODS In this study, we utilize a gene editing tool, transcription activator-like effector nucleases (TALENs), to generate human hepatoma cells with
Autor:
Hong Zhao, Leiliang Zhang, Guoyang Wu, Shaoyong Li, Kattareeya Kumthip, Ethan M. Weinberg, Wen-Chi Chen, Mark A. Brockman, Wenyu Lin, Nikolaus Jilg, Lee F. Peng, Jorge Méndez-Navarro, Detlef Schuppan, Kaku Goto, Raymond T. Chung
Publikováno v:
The Journal of Biological Chemistry
HIV/HCV coinfection leads to accelerated hepatic fibrosis progression, with higher rates of cirrhosis, liver failure, and liver death than does HCV mono-infection. However, the profibrogenic role of HIV on hepatocytes and hepatic stellate cells (HSC)