Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Pavel Vodicka"'
Autor:
Ludmila Vodickova, Andrea Cumova, Sivaramakrishna Rachakonda, Pavel Soucek, Rajesh Kumar, Sona Vodenkova, Michal Kroupa, Andrea Rossnerova, Kari Hemminki, Vaclav Liska, Veronika Vymetalkova, Kristyna Tomasova, Pavel Vodicka
Publikováno v:
Mutagenesis. 35:491-497
Disruption of telomere length (TL) homeostasis in peripheral blood lymphocytes has been previously assessed as a potential biomarker of breast cancer (BC) risk. The present study addressed the relationship between lymphocyte TL (LTL), prognosis and c
Telomere maintenance in interplay with DNA repair in pathogenesis and treatment of colorectal cancer
Publikováno v:
Mutagenesis. 35:261-271
Colorectal cancer (CRC) continues to be one of the leading malignancies and causes of tumour-related deaths worldwide. Both impaired DNA repair mechanisms and disrupted telomere length homeostasis represent key culprits in CRC initiation, progression
Autor:
Simona Susova, Linda Bartu, Jan Kral, Pavel Soucek, Rajesh Kumar, Ludmila Vodickova, Miroslav Levy, Tomas Buchler, Fabio Rosa, Petra Bendova, Veronika Vymetalkova, Pavel Vodicka, David J. Hughes, Alessio Naccarati, Barbara Pardini
Publikováno v:
Mutagenesis. 35:273-281
The chemotherapeutic efficacy in colorectal cancer (CRC) is limited due to the inter-individual variability in drug response and the development of tumour resistance. ATP-binding cassette (ABC) transporters are crucial in the development of resistanc
Autor:
Alicja Wolk, Edward Giovannucci, Li Li, Polly A. Newcomb, Kenneth Offit, Clemens Schafmayer, Vicente Martín, Sergi Castellví-Bel, Daniel D. Buchanan, Mingyang Song, Qianchuan He, Martha L. Slattery, Volker Arndt, Anna H. Wu, Amit Joshi, David A. Drew, D. Timothy Bishop, Annika Lindblom, Temitope O. Keku, Jochen Hampe, Ozan Dikilitas, Douglas A. Corley, John B. Harley, Hakon Hakonarson, Steven Gallinger, Noralane M. Lindor, Ian B. Stanaway, Jeffrey K. Lee, Sonja I. Berndt, Veronika Vymetalkova, Syed H.E. Zaidi, Jessica Minnier, Daniel J. Schaid, Ludmila Vodickova, John D. Potter, Heather Hampel, Christopher I. Li, Frank D. Mentch, Wei-Qi Wei, Cornelia M. Ulrich, Marc J. Gunter, Robert E. Schoen, Catherine M. Tangen, Victor Moreno, Shuji Ogino, Tabitha A. Harrison, Albert de la Chapelle, Pavel Vodicka, Andrew T. Chan, Keith R. Curtis, Elisabeth A. Rosenthal, Jenny Chang-Claude, David C. Muller, Paul D.P. Pharoah, Roger L. Milne, David Duggan, Eric B. Larson, David R. Crosslin, Andrea Gsur, Stéphane Bézieau, Graham G. Giles, Robert J. MacInnis, Bahram Namjou, Christopher H. Dampier, Gail P. Jarvik, Andrea N. Burnett-Hartman, Richard B. Hayes, Fränzel J.B. Van Duijnhoven, Wendy K. Chung, Michael Hoffmeister, Mark A. Jenkins, Mathieu Lemire, Thomas J. Hudson, Elizabeth A. Platz, Neil Murphy, Graham Casey, Michael O. Woods, Aung Ko Win, Flora Qu, Li Hsu, Emily White, Peter T. Campbell, Lori C. Sakoda, Jane C. Figueiredo, Minta Thomas, Jeroen R. Huyghe, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Corinne E. Joshu, Yu Ru Su, Ulrike Peters, Stephen B. Gruber, Demetrius Albanes, Stephen N. Thibodeau, Antoni Castells, Hermann Brenner
Publikováno v:
Am J Hum Genet
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying individuals at low and high risk of developing CRC, as they can then be offered targeted screening and interventions to address their risks of developing disease (if
Autor:
Pavel Vodicka, Barbara Pardini, Szimonetta Turoczi, Antonio Francavilla, Sonia Tarallo, Alessio Naccarati
Publikováno v:
Mutagenesis. 35:243-260
The circulating human transcriptome, which includes both coding and non-coding RNA (ncRNA) molecules, represents a rich source of potential biomarkers for colorectal cancer (CRC) that has only recently been explored. In particular, the release of RNA
Autor:
Yasmeen Niazi, Hauke Thomsen, Bozena Smolkova, Ludmila Vodickova, Sona Vodenkova, Michal Kroupa, Veronika Vymetalkova, Alena Kazimirova, Magdalena Barancokova, Katarina Volkovova, Marta Staruchova, Per Hoffmann, Markus M. Nöthen, Maria Dusinska, Ludovit Musak, Pavel Vodicka, Kari Hemminki, Asta Försti
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Frontiers in Genetics
Frontiers in Genetics
DNA damage and unrepaired or insufficiently repaired DNA double-strand breaks as well as telomere shortening contribute to the formation of structural chromosomal aberrations (CAs). Non-specific CAs have been used in the monitoring of individuals exp
Autor:
Alena Kazimirova, Magdalena Barancokova, Sona Vodenkova, Marta Staruchova, Markus M. Nöthen, Maria Dusinska, Asta Försti, Ludovit Musak, Ludmila Vodickova, Per Hoffmann, Yasmeen Niazi, Kari Hemminki, Katarina Volkovova, Pavel Vodicka, Hauke Thomsen, Michal Kroupa, Bozena Smolkova, Veronika Vymetalkova
Publikováno v:
Environmental and Molecular Mutagenesis. 60:17-28
Chromosomal aberrations (CAs) in human peripheral blood lymphocytes (PBL) measured with the conventional cytogenetic assay have been used for human biomonitoring of genotoxic exposure for decades. CA frequency in peripheral blood is a marker of cance
Autor:
Katerina Lickova, Pavel Soucek, Andrea Cumova, Alena Opattova, Ludmila Vodickova, Pavel Vodicka, Barbara Pardini, Katerina Kopeckova, Renata Kozevnikovova, Veronika Vymetalkova, Miloslav Ambrus, Veronika Bouskova, Alessio Naccarati
Publikováno v:
Mutagenesis. 36(4)
Breast cancer (BC) is the most frequent malignancy in women accounting for approximately 2 million new cases worldwide annually. Several genetic, epigenetic and environmental factors are known to be involved in BC development and progression, includi
Autor:
John P. Neoptolemos, Markus W. Büchler, Jakob R. Izbicki, Ben Schöttker, Cosmeri Rizzato, Cornelia Schroeder, Salvatore Paiella, Hanneke W. M. van Laarhoven, William Greenhalf, Simona Bursi, Renata Talar-Wojnarowska, Christos Dervenis, Ludmila Vodickova, Francesca Tavano, Giulia Martina Cavestro, Thilo Hackert, Claudio Pasquali, Ewa Małecka-Panas, Gabriele Capurso, Andrea Mambrini, Daniele Campa, Andrea Padoan, Ioannis S. Papanikolaou, Raffaele Pezzilli, Péter Hegyi, Beatrice Mohelnikova-Duchonova, Federica Gemignani, Michael F. Nentwich, Pavel Vodicka, Stefano Landi, Richárd Szmola, Anna Caterina Milanetto, Eithne Costello, Rudolf Kaaks, Laura Ginocchi, Bernd Holleczek, Erika Darvasi, Verena Katzke, Evaristo Maiello, Manuel Gentiluomo, Ondrej Strouhal, Orazio Palmieri, Juozas Kupcinskas, Alice Alessandra Galeotti, Viktor Hlavac, George Theodoropoulos, Audrius Ivanauskas, Maria Gazouli, Ferenc Izbéki, Federico Canzian, Oliver Strobel, Ofure Obazee, Martin Lovecek, Timothy J. Key, Domenica Gioffreda, Pavel Soucek, Ugo Boggi, Krzysztof Jamroziak, Cosimo Sperti, Maarten F. Bijlsma, Yogesh K. Vashist, Andrea Szentesi, Hermann Brenner, Livia Archibugi, Giuseppe Vanella, Daniela Basso
Publikováno v:
Journal of medical genetics, 58(6), 369-377. BMJ Publishing Group
JOURNAL OF MEDICAL GENETICS
JOURNAL OF MEDICAL GENETICS
BackgroundMost cases of pancreatic ductal adenocarcinoma (PDAC) are asymptomatic in early stages, and the disease is typically diagnosed in advanced phases, resulting in very high mortality. Tools to identify individuals at high risk of developing PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a267bd63e2a9e7418632e88a73d56f47
https://hdl.handle.net/11568/1072532
https://hdl.handle.net/11568/1072532
Autor:
Asta Försti, Ludmila Vodickova, Alena Kazimirova, Markus M. Nöthen, Marta Staruchova, Per Hoffmann, Yasmeen Niazi, Katarina Volkovova, Kari Hemminki, Maria Dusinska, Veronika Vymetalkova, Soňa Vodenkova, Ludovit Musak, Hauke Thomsen, Pavel Vodicka, Michal Kroupa, Bozena Smolkova, Magdalena Barancokova
Publikováno v:
Mutagenesis. 34(4)
Non-specific structural chromosomal aberrations (CAs) observed in peripheral blood lymphocytes of healthy individuals can be either chromosome-type aberrations (CSAs) or chromatid-type aberrations (CTAs) depending on the stage of cell division they a