Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Pavel Vodicka"'
Autor:
Ludmila Vodickova, Andrea Cumova, Sivaramakrishna Rachakonda, Pavel Soucek, Rajesh Kumar, Sona Vodenkova, Michal Kroupa, Andrea Rossnerova, Kari Hemminki, Vaclav Liska, Veronika Vymetalkova, Kristyna Tomasova, Pavel Vodicka
Publikováno v:
Mutagenesis. 35:491-497
Disruption of telomere length (TL) homeostasis in peripheral blood lymphocytes has been previously assessed as a potential biomarker of breast cancer (BC) risk. The present study addressed the relationship between lymphocyte TL (LTL), prognosis and c
Autor:
Alicja Wolk, Edward Giovannucci, Li Li, Polly A. Newcomb, Kenneth Offit, Clemens Schafmayer, Vicente Martín, Sergi Castellví-Bel, Daniel D. Buchanan, Mingyang Song, Qianchuan He, Martha L. Slattery, Volker Arndt, Anna H. Wu, Amit Joshi, David A. Drew, D. Timothy Bishop, Annika Lindblom, Temitope O. Keku, Jochen Hampe, Ozan Dikilitas, Douglas A. Corley, John B. Harley, Hakon Hakonarson, Steven Gallinger, Noralane M. Lindor, Ian B. Stanaway, Jeffrey K. Lee, Sonja I. Berndt, Veronika Vymetalkova, Syed H.E. Zaidi, Jessica Minnier, Daniel J. Schaid, Ludmila Vodickova, John D. Potter, Heather Hampel, Christopher I. Li, Frank D. Mentch, Wei-Qi Wei, Cornelia M. Ulrich, Marc J. Gunter, Robert E. Schoen, Catherine M. Tangen, Victor Moreno, Shuji Ogino, Tabitha A. Harrison, Albert de la Chapelle, Pavel Vodicka, Andrew T. Chan, Keith R. Curtis, Elisabeth A. Rosenthal, Jenny Chang-Claude, David C. Muller, Paul D.P. Pharoah, Roger L. Milne, David Duggan, Eric B. Larson, David R. Crosslin, Andrea Gsur, Stéphane Bézieau, Graham G. Giles, Robert J. MacInnis, Bahram Namjou, Christopher H. Dampier, Gail P. Jarvik, Andrea N. Burnett-Hartman, Richard B. Hayes, Fränzel J.B. Van Duijnhoven, Wendy K. Chung, Michael Hoffmeister, Mark A. Jenkins, Mathieu Lemire, Thomas J. Hudson, Elizabeth A. Platz, Neil Murphy, Graham Casey, Michael O. Woods, Aung Ko Win, Flora Qu, Li Hsu, Emily White, Peter T. Campbell, Lori C. Sakoda, Jane C. Figueiredo, Minta Thomas, Jeroen R. Huyghe, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Corinne E. Joshu, Yu Ru Su, Ulrike Peters, Stephen B. Gruber, Demetrius Albanes, Stephen N. Thibodeau, Antoni Castells, Hermann Brenner
Publikováno v:
Am J Hum Genet
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
American Journal of Human Genetics, 107(3), 432-444
American Journal of Human Genetics 107 (2020) 3
Accurate colorectal cancer (CRC) risk prediction models are critical for identifying individuals at low and high risk of developing CRC, as they can then be offered targeted screening and interventions to address their risks of developing disease (if
Autor:
Stephanie J. Weinstein, Rami Nassir, Fredrick R. Schumacher, Neil Murphy, M. Henar Alonso, Satu Männistö, Hedy S. Rennert, Manish Gala, Phyllis J. Goodman, Albert de la Chapelle, Tilman Kühn, Fränzel J.B. Van Duijnhoven, Paul D.P. Pharoah, Anshul Kundaje, Juergen Boehm, W. James Gauderman, Mark A. Jenkins, Vittorio Perduca, Polly A. Newcomb, Amanda I. Phipps, Christopher I. Li, Douglas F. Easton, Antonia Trichopoulou, Kristin E. Anderson, Daniel D. Buchanan, Peter C. Scacheri, William M. Grady, Liher Imaz, Veronika Vymetalkova, Wan-Ling Hsu, Prudence R. Carr, Martha L. Slattery, Keith R. Curtis, Elizabeth A. Platz, Sai Chen, Graham G. Giles, D. Timothy Bishop, David M. Levine, Michael Hoffmeister, Duncan C. Thomas, Roger L. Milne, Michael O. Woods, Michael C. Bassik, Andrea Gsur, Dallas R. English, David V. Conti, Sébastien Küry, Wolfgang Lieb, Jochen Hampe, Coral Arnau-Collell, Steven Gallinger, Emily White, John S. Grove, Antoni Castells, Hermann Brenner, Amanda E. Toland, Noralane M. Lindor, Aurora Perez-Cornago, David Duggan, Temitope O. Keku, Edith J. M. Feskens, Heather Hampel, Korbinian Weigl, Li Li, Li Hsu, Conghui Qu, Peter T. Campbell, John L. Hopper, Volker Arndt, Jenny Chang-Claude, Lorena Moreno, John A. Baron, Stephen N. Thibodeau, Robert E. Schoen, Jeroen R. Huyghe, Rachel Pearlman, Sanford D. Markowitz, Amanda J. Cross, Stephan Buch, Barbara L. Banbury, Thomas J. Hudson, Yu Ru Su, Marc J. Gunter, Stephen B. Gruber, Heiner Boeing, Demetrius Albanes, Wen Yi Huang, Sergi Castellví-Bel, Jane C. Figueiredo, Catherine M. Tangen, Andrew T. Chan, Annika Lindblom, Deborah A. Nickerson, Richard B. Hayes, Lori C. Sakoda, Flavio Lejbkowicz, Salvatore Panico, Alicja Wolk, Kenneth Offit, John D. Potter, Leon Raskin, Bette J. Caan, Clemens Schafmayer, Mingyang Song, Lihong Qi, Elio Riboli, Hyun Min Kang, Sophia Harlid, Pavel Vodicka, Ludmila Vodickova, Cornelia M. Ulrich, Stephanie L. Schmit, Victor Moreno, Anna H. Wu, Brenda Diergaarde, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Mazda Jenab, Amit Joshi, Stefanie Brezina, Stephanie A. Bien, Charles Kooperberg, Shuji Ogino, Daniela Seminara, Graham Casey, Andrea N. Burnett-Hartman, Robert W. Haile, Ulrike Peters, Gad Rennert, Tabitha A. Harrison, Ross L. Prentice, Yi Lin, Antonio Agudo, Gonçalo R. Abecasis, Sonja I. Berndt, Stephen J. Chanock, Stéphane Bézieau, Patrick S. Parfrey, Richard Barfield, Marie-Christine Boutron-Ruault
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Gut
Gut 70 (2021) 7
Gut, 70(7), 1325-1334
Universidad de Barcelona
Gut
Gut 70 (2021) 7
Gut, 70(7), 1325-1334
ObjectiveAn understanding of the etiologic heterogeneity of colorectal cancer (CRC) is critical for improving precision prevention, including individualized screening recommendations and the discovery of novel drug targets and repurposable drug candi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848446aa02775ab8c2114dd85e926946
http://hdl.handle.net/2445/179342
http://hdl.handle.net/2445/179342
Autor:
Li Li, Mark A. Jenkins, Jeroen R. Huyghe, Sang-Hee Cho, Alicja Wolk, Kenneth Offit, Rachel Pearlman, D. Timothy Bishop, Jenny Chang-Claude, Jiandong Bao, Soo-Chin Lee, Fangqin Wang, Martha L. Slattery, Stephan Buch, Hyun Min Kang, Yuan Yuan, Fredrick R. Schumacher, Gonçalo R. Abecasis, John D. Potter, Fränzel J.B. Van Duijnhoven, Robert E. Schoen, Gad Rennert, Heather Hampel, Graham G. Giles, Neil Murphy, Tabitha A. Harrison, Ellen Kampman, Polly A. Newcomb, Wei Zheng, Weiqiang Lin, Zhishan Chen, Edith J. M. Feskens, Michael Hoffmeister, Hermann Brenner, Ulrike Peters, Paul D.P. Pharoah, Temitope O. Keku, Graham Casey, Pavel Vodicka, Annika Lindblom, Sonja I. Berndt, Ludmila Vodickova, Yu Ru Su, Phyllis J. Goodman, Albert de la Chapelle, Michael O. Woods, Sergi Castellví-Bel, Jirong Long, Andrea Gsur, Cornelia M. Ulrich, Stephanie L. Schmit, Stephen B. Gruber, Stephen J. Chanock, Qiuyin Cai, Victor Moreno, Xiaoliang Wang, Xingyi Guo, David V. Conti, Jochen Hampe, Mark A. Guinter, Andrea N. Burnett-Hartman, Demetrius Albanes, Hyeong Rok Kim, Veronika Vymetalkova, Bethany Van Guelpen, Kala Visvanathan, Loic Le Marchand, Stéphane Bézieau, Deborah A. Nickerson, Roger L. Milne, Wanqing Wen, Lori C. Sakoda, Stephanie A. Bien, Li Hsu, Emily White, Conghui Qu, Peter T. Campbell, Christopher I. Li, Elizabeth A. Platz, Clemens Schafmayer, Mengqiu Bai, Steven Gallinger, Noralane M. Lindor, Marc J. Gunter, Catherine M. Tangen, Andrew T. Chan, Richard B. Hayes
Publikováno v:
Gastroenterology 160 (2021) 4
Gastroenterology
Gastroenterology, 160(4), 1164-1178.e6
Gastroenterology
Gastroenterology, 160(4), 1164-1178.e6
BACKGROUND AND AIMS: Susceptibility genes and the underlying mechanisms for the majority of risk loci identified by genome-wide association studies (GWAS) for colorectal cancer (CRC) risk remain largely unknown. We conducted a transcriptome-wide asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75337edf52b684019bb9ec5dcaa55e77
https://research.wur.nl/en/publications/identifying-novel-susceptibility-genes-for-colorectal-cancer-risk
https://research.wur.nl/en/publications/identifying-novel-susceptibility-genes-for-colorectal-cancer-risk
Autor:
Barbara L. Banbury, Christopher I. Li, Joshua A. Bell, Elizabeth A. Platz, Kenneth Offit, Stephen B. Gruber, Gad Rennert, Tabitha A. Harrison, Li Hsu, Emily White, Conghui Qu, Peter T. Campbell, Li Li, Nicholas J. Timpson, Sonja I. Berndt, Roger L. Milne, Jeroen R. Huyghe, Steven Gallinger, Pavel Vodicka, Anne M. May, Loic Le Marchand, Annika Lindblom, Graham Casey, Lori C. Sakoda, Wei Zheng, Fränzel J.B. van Duijnhoven, Corinne E. Joshu, Martha L. Slattery, Amanda I. Phipps, Bethany Van Guelpen, Marc J. Gunter, Hermann Brenner, John D. Potter, Vicente Martín, Andrew T. Chan, Temitope O. Keku, Ludmila Vodickova, D. Timothy Bishop, Graham G. Giles, Susan M. Gapstur, Daniel D. Buchanan, Hansong Wang, Catherine M. Tangen, Alicja Wolk, Michael O. Woods, Sun-Seog Kweon, Jane C. Figueiredo, Stéphane Bézieau, Caroline J. Bull, Wen-Yi Huang, Michael Hoffmeister, Cornelia M. Ulrich, Robert E. Schoen, Eleanor Sanderson, Demetrius Albanes, Victor Moreno, Jenny Chang-Claude, Tilman Kühn, Clemens Schafmayer, J. Ramón Quirós, Shuji Ogino, Polly A. Newcomb, Ulrike Peters, Elio Riboli, Jochen Hampe, Heather Hampel, Kala Visvanathan, Sergi Castellví-Bel, Anna H. Wu, Neil Murphy, Mark A. Jenkins, Kostas Tsilidis, Andrea Gsur, Andrea N. Burnett-Hartman, George Davey Smith, Albert de la Chapelle, Emma E. Vincent, Amanda J. Cross
Publikováno v:
BMC Medicine 18 (2020) 1
Dipòsit Digital de la UB
Universidad de Barcelona
BMC Medicine
Bull, C J, Bell, J A, Sanderson, E, Davey Smith, G, Timpson, N J, Gunter, M J & al., E 2020, ' Adiposity, metabolites, and colorectal cancer risk : Mendelian randomization study ', BMC Medicine, vol. 18, 396 (2020) . https://doi.org/10.1186/s12916-020-01855-9
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Medicine, 18(1)
Dipòsit Digital de la UB
Universidad de Barcelona
BMC Medicine
Bull, C J, Bell, J A, Sanderson, E, Davey Smith, G, Timpson, N J, Gunter, M J & al., E 2020, ' Adiposity, metabolites, and colorectal cancer risk : Mendelian randomization study ', BMC Medicine, vol. 18, 396 (2020) . https://doi.org/10.1186/s12916-020-01855-9
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Medicine, 18(1)
Background Higher adiposity increases the risk of colorectal cancer (CRC), but whether this relationship varies by anatomical sub-site or by sex is unclear. Further, the metabolic alterations mediating the effects of adiposity on CRC are not fully un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ac1dc5327f394332b4f3e350bf0ac0
https://research.wur.nl/en/publications/adiposity-metabolites-and-colorectal-cancer-risk-mendelian-random
https://research.wur.nl/en/publications/adiposity-metabolites-and-colorectal-cancer-risk-mendelian-random
Autor:
John P. Neoptolemos, Markus W. Büchler, Jakob R. Izbicki, Ben Schöttker, Cosmeri Rizzato, Cornelia Schroeder, Salvatore Paiella, Hanneke W. M. van Laarhoven, William Greenhalf, Simona Bursi, Renata Talar-Wojnarowska, Christos Dervenis, Ludmila Vodickova, Francesca Tavano, Giulia Martina Cavestro, Thilo Hackert, Claudio Pasquali, Ewa Małecka-Panas, Gabriele Capurso, Andrea Mambrini, Daniele Campa, Andrea Padoan, Ioannis S. Papanikolaou, Raffaele Pezzilli, Péter Hegyi, Beatrice Mohelnikova-Duchonova, Federica Gemignani, Michael F. Nentwich, Pavel Vodicka, Stefano Landi, Richárd Szmola, Anna Caterina Milanetto, Eithne Costello, Rudolf Kaaks, Laura Ginocchi, Bernd Holleczek, Erika Darvasi, Verena Katzke, Evaristo Maiello, Manuel Gentiluomo, Ondrej Strouhal, Orazio Palmieri, Juozas Kupcinskas, Alice Alessandra Galeotti, Viktor Hlavac, George Theodoropoulos, Audrius Ivanauskas, Maria Gazouli, Ferenc Izbéki, Federico Canzian, Oliver Strobel, Ofure Obazee, Martin Lovecek, Timothy J. Key, Domenica Gioffreda, Pavel Soucek, Ugo Boggi, Krzysztof Jamroziak, Cosimo Sperti, Maarten F. Bijlsma, Yogesh K. Vashist, Andrea Szentesi, Hermann Brenner, Livia Archibugi, Giuseppe Vanella, Daniela Basso
Publikováno v:
Journal of medical genetics, 58(6), 369-377. BMJ Publishing Group
JOURNAL OF MEDICAL GENETICS
JOURNAL OF MEDICAL GENETICS
BackgroundMost cases of pancreatic ductal adenocarcinoma (PDAC) are asymptomatic in early stages, and the disease is typically diagnosed in advanced phases, resulting in very high mortality. Tools to identify individuals at high risk of developing PD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a267bd63e2a9e7418632e88a73d56f47
https://hdl.handle.net/11568/1072532
https://hdl.handle.net/11568/1072532
Autor:
Verena Katzke, Jakob R. Izbicki, Francesca Tavano, Rita T. Lawlor, Thilo Hackert, Raffaella Alessia Zuppardo, Giulia Martina Cavestro, Federico Canzian, Frederike Dijk, Martin Oliverius, George Theodoropoulos, Pavel Soucek, Manuel Gentiluomo, Rudolf Kaaks, Erika Darvasi, Yogesh K. Vashist, Bill Greenhalf, Juozas Kupcinskas, Maurizio Lucchesi, Borislav Rusev, Andrea Szentesi, Gabriele Capurso, Ewa Małecka-Panas, Lucia Moletta, Beatrice Mohelnikova-Duchonova, Franco Bambi, Ugo Boggi, Alba Ballerini, Krzysztof Jamroziak, Ben Schöttker, Simona Bursi, Raffaele Pezzilli, Gyula Farkas, Dania Bozzato, Áron Vincze, Stefano Landi, Anna Caterina Milanetto, Péter Hegyi, Michael F. Nentwich, Laura Ginocchi, Pavel Vodicka, Stefania Moz, Ludmila Vodickova, Hermann Brenner, Olivier R. Busch, Viktor Hlavac, Audrius Ivanauskas, John P. Neoptolemos, Domenica Gioffreda, Ofure Obazee, Livia Archibugi, Nathalia A. Giese, Giuseppe Vanella, Xin Gao, Renata Talar-Wojnarowska, Angelo Andriulli, Oliver Strobel, Daniele Campa, Maria Gazouli
Publikováno v:
International journal of cancer. Journal international du cancer, 147(8), 2065-2074. Wiley-Liss Inc.
Early onset pancreatic cancer (EOPC) is a rare disease with a very high mortality rate. Almost nothing is known on the genetic susceptibility of EOPC, therefore we performed a genome-wide association study (GWAS) to identify novel genetic variants sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eca8922334c7a770aa6db6ad743c1fad
http://hdl.handle.net/11577/3343599
http://hdl.handle.net/11577/3343599
Autor:
Asta Försti, Ludmila Vodickova, Alena Kazimirova, Markus M. Nöthen, Marta Staruchova, Per Hoffmann, Yasmeen Niazi, Katarina Volkovova, Kari Hemminki, Maria Dusinska, Veronika Vymetalkova, Soňa Vodenkova, Ludovit Musak, Hauke Thomsen, Pavel Vodicka, Michal Kroupa, Bozena Smolkova, Magdalena Barancokova
Publikováno v:
Mutagenesis. 34(4)
Non-specific structural chromosomal aberrations (CAs) observed in peripheral blood lymphocytes of healthy individuals can be either chromosome-type aberrations (CSAs) or chromatid-type aberrations (CTAs) depending on the stage of cell division they a
Autor:
Asta Försti, Tharmila Sanmuganantham, Farhat V N Din, Miguel Inacio da Silva Filho, Alessio Naccarati, Maria Timofeeva, Malcolm G. Dunlop, Alexander N.R. Weber, Hermann Brenner, Jan Wehkamp, Veronika Polakova-Vymetálkova, Kari Hemminki, Lina Jansen, Jenny Chang-Claude, Markus W. Löffler, Calogerina Catalano, Michael Hoffmeister, Tica Pichulik, Stefanie Huhn, Ludmila Vodickova, Katerina Jiraskova, L Courth, Susan M. Farrington, Barbara Pardini, Pavel Vodicka
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0199350 (2018)
Huhn, S, Da Silva Filho, M I, Sanmuganantham, T, Pichulik, T, Catalano, C, Pardini, B, Naccarati, A, Polakova-vymetálkova, V, Jiraskova, K, Vodickova, L, Vodicka, P, Löffler, M W, Courth, L, Wehkamp, J, Din, F V N, Timofeeva, M, Farrington, S M, Jansen, L, Hemminki, K, Chang-claude, J, Brenner, H, Hoffmeister, M, Dunlop, M G, Weber, A N R, Försti, A & Ahmad, A (ed.) 2018, ' Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer ', PLoS ONE, vol. 13, no. 6, pp. e0199350 . https://doi.org/10.1371/journal.pone.0199350
PLoS ONE
Huhn, S, Da Silva Filho, M I, Sanmuganantham, T, Pichulik, T, Catalano, C, Pardini, B, Naccarati, A, Polakova-vymetálkova, V, Jiraskova, K, Vodickova, L, Vodicka, P, Löffler, M W, Courth, L, Wehkamp, J, Din, F V N, Timofeeva, M, Farrington, S M, Jansen, L, Hemminki, K, Chang-claude, J, Brenner, H, Hoffmeister, M, Dunlop, M G, Weber, A N R, Försti, A & Ahmad, A (ed.) 2018, ' Coding variants in NOD-like receptors: An association study on risk and survival of colorectal cancer ', PLoS ONE, vol. 13, no. 6, pp. e0199350 . https://doi.org/10.1371/journal.pone.0199350
PLoS ONE
Nod-like receptors (NLRs) are important innate pattern recognition receptors and regulators of inflammation or play a role during development. We systematically analysed 41 non-synonymous single nucleotide polymorphisms (SNPs) in 21 NLR genes in a Cz
Autor:
Arantza Farina Sarasqueta, Tom van Wezel, Clara Ruiz-Ponte, Stephanie A. Schubert, Juul T. Wijnen, Sergi Castellví-Bel, Rolf H. Sijmons, Hans Morreau, Bruce H. R. Wolffenbuttel, Stijn Crobach, Melanie M. van der Klauw, Arnoud Boot, Jan Oosting, Noel F C C de Miranda, Fadwa A. Elsayed, Frederik J. Hes, Hans F. A. Vasen, Maartje Nielsen, Pavel Vodicka, Rolf H. A. M. Vossen, Carli M. J. Tops, Ronald van Eijk, Malcolm G. Dunlop, Ian Tomlinson, Dina Ruano
Publikováno v:
British Journal of Cancer
Schubert, S A, Ruano, D, Elsayed, F A, Boot, A, Crobach, S, Sarasqueta, A F, Wolffenbuttel, B, van der Klauw, M M, Oosting, J, Tops, C M, van Eijk, R, Vasen, H F, Vossen, R H, Nielsen, M, Castellví-Bel, S, Ruiz-Ponte, C, Tomlinson, I, Dunlop, M G, Vodicka, P, Wijnen, J T, Hes, F J, Morreau, H, de Miranda, N F, Sijmons, R H & van Wezel, T 2017, ' Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia ', British Journal of Cancer . https://doi.org/10.1038/bjc.2017.240
British Jounal of Cancer, 117(8), 1215-1223. Nature Publishing Group
British Journal of Cancer, 117(8), 1215-1223
British journal of cancer, 117(6), 876-884. Nature Publishing Group
Schubert, S A, Ruano, D, Elsayed, F A, Boot, A, Crobach, S, Sarasqueta, A F, Wolffenbuttel, B, van der Klauw, M M, Oosting, J, Tops, C M, van Eijk, R, Vasen, H F, Vossen, R H, Nielsen, M, Castellví-Bel, S, Ruiz-Ponte, C, Tomlinson, I, Dunlop, M G, Vodicka, P, Wijnen, J T, Hes, F J, Morreau, H, de Miranda, N F, Sijmons, R H & van Wezel, T 2017, ' Evidence for genetic association between chromosome 1q loci and predisposition to colorectal neoplasia ', British Journal of Cancer . https://doi.org/10.1038/bjc.2017.240
British Jounal of Cancer, 117(8), 1215-1223. Nature Publishing Group
British Journal of Cancer, 117(8), 1215-1223
British journal of cancer, 117(6), 876-884. Nature Publishing Group
BACKGROUND: A substantial fraction of familial colorectal cancer (CRC) and polyposis heritability remains unexplained. This study aimed to identify predisposing loci in patients with these disorders.METHODS: Homozygosity mapping was performed using 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27b339caa03287c7a985f07c59a3502
https://hdl.handle.net/1887/115104
https://hdl.handle.net/1887/115104