Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Pavel Vodicka"'
Publikováno v:
Molecular Aspects of Medicine. 69:73-92
Colorectal carcinogenesis is a multistep process involving the accumulation of genetic alterations over time that ultimately leads to disease progression and metastasis. Binding of transcription factors to gene promoter regions alone cannot explain t
Autor:
Rastislav Dzijak, Zdenek Hodny, Jiri Bartek, Alena Moudra, Vojtech Tambor, Miroslav Pribyl, Lukas Rob, Sona Hubackova, Lenka Kyjacova, Jiri Svec, Pavel Vodicka, Barbora Salovska, Hynek Strnad, Radka Vaclavikova, Terezie Imrichova
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 13, Iss 7, Pp 1467-1489 (2019)
Molecular Oncology, Vol 13, Iss 7, Pp 1467-1489 (2019)
Radiation and chemotherapy represent standard‐of‐care cancer treatments. However, most patients eventually experience tumour recurrence, treatment failure and metastatic dissemination with fatal consequences. To elucidate the molecular mechanisms
Autor:
Vlasta Korenkova, Vaclav Liska, Julius Spicak, Katerina Jiraskova, Vendula Novosadova, Miroslav Levy, Pavel Vodicka, Veronika Veskrnova, Jan Kral, Alena Opattova, Lucie Langerova, Michaela Schneiderova, Jana Slyskova, Veronika Vymetalkova
Publikováno v:
Carcinogenesis. 39:1359-1367
MicroRNA (miRNA) profiling represents a promising source of cancer-related biomarkers. miRNA signatures are specific for each cancer type and subgroups of patients with diverse treatment sensitivity. Yet this miRNA potential has not been satisfactori
Autor:
John P. Neoptolemos, Krzysztof Jamroziak, Manuel Gentiluomo, Edita Kreivenaite, Oliver Strobel, Martin Lovecek, Núria Malats, Rita T. Lawlor, Angelica Macauda, Yogesh K. Vashist, Sabrina Gloria Giulia Testoni, Paolo Giorgio Arcidiacono, Raffaele Pezzilli, Gabriele Capurso, George Theodoropoulos, Andrea Szentesi, Giuseppe Vanella, Michael F. Nentwich, Pavel Vodicka, Luca Morelli, Audrius Ivanauskas, Angelo Andriulli, Giulia Martina Cavestro, Emanuele Federico Kauffmann, Renata Talar-Wojnarowska, Raffaella Alessia Zuppardo, Pavel Soucek, Viktor Hlavac, Daniele Campa, Laura Pistoni, PanGenEU Study Investigators, Evangelina López de Maturana, Milena Di Leo, Livia Archibugi, Maria Gazouli, Federico Canzian, Péter Hegyi, Cosimo Sperti, Anna Caterina Milanetto, László Gajdán, Domenica Gioffreda, Martin Oliverius, Beatrice Mohelnikova-Duchonova, Dania Bozzato, Maria Chiara Petrone, Stefano Landi, Thilo Hackert, Luca Pollina, Hermann Brenner, Ye Lu, Cristian Gheorghe, Daniela Basso, Giuseppe Malleo, Erika Darvasi, Ludmila Vodickova, Juozas Kupcinskas, Jakob R. Izbicki, Francesca Tavano
Pancreatic ductal adenocarcinoma (PDAC) is among the most lethal cancers. Its poor prognosis is predominantly due to the fact that most patients remain asymptomatic until the disease reaches an advanced stage, alongside the lack of early markers and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec9bf21e1100c0e6e8621bd709fa821
http://hdl.handle.net/11562/1045679
http://hdl.handle.net/11562/1045679
Autor:
Ludmila Vodickova, Tomas Buchler, Miloslav Levy, Alessio Naccarati, Pavel Soucek, Stefano Landi, Vaclav Liska, Pavel Vodicka, Veronika Vymetalkova, Petra Bendova, Jachym Rosendorf, Simona Susova, Pavel Skrobanek, Barbara Pardini, Jan Kral
One of the principal mechanisms of chemotherapy resistance in highly frequent solid tumors, such as colorectal cancer (CRC), is the decreased activity of drug transport into tumor cells due to low expression of important membrane proteins, such as so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2712ed29851e7eb9a3e768856225a55a
http://hdl.handle.net/2318/1786621
http://hdl.handle.net/2318/1786621
Autor:
Ludmila Vodickova, Veronika Vymetalkova, Pavel Vodicka, Fabian Caja, Jan Kral, Alessio Naccarati
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5561, p 5561 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The phenotypic effects of single nucleotide polymorphisms (SNPs) in the development of sporadic solid cancers are still scarce. The aim of this review was to summarise and analyse published data on the associations between SNPs in mismatch repair gen
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 3260, p 3260 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 3260, p 3260 (2020)
Colorectal cancer (CRC) is a malignant disease with an incidence of over 1.8 million new cases per year worldwide. CRC outcome is closely related to the respective stage of CRC and is more favorable at less advanced stages. Detection of early colorec
Autor:
Alena Opattova, Veronika Vymetalkova, Michaela Schneiderova, Markéta Urbanová, Kristyna Tomasova, Ludmila Vodickova, Pavol Makovicky, Rudolf Stetina, Klara Kostovcikova, Anna Siskova, Pavel Vodicka, Michal Kroupa
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2473, p 2473 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
Oxidative stress with subsequent premutagenic oxidative DNA damage has been implicated in colorectal carcinogenesis. The repair of oxidative DNA damage is initiated by lesion-specific DNA glycosylases (hOGG1, NTH1, MUTYH). The direct evidence of the
Autor:
Barbara L. Banbury, Christopher I. Li, Joshua A. Bell, Elizabeth A. Platz, Kenneth Offit, Stephen B. Gruber, Gad Rennert, Tabitha A. Harrison, Li Hsu, Emily White, Conghui Qu, Peter T. Campbell, Li Li, Nicholas J. Timpson, Sonja I. Berndt, Roger L. Milne, Jeroen R. Huyghe, Steven Gallinger, Pavel Vodicka, Anne M. May, Loic Le Marchand, Annika Lindblom, Graham Casey, Lori C. Sakoda, Wei Zheng, Fränzel J.B. van Duijnhoven, Corinne E. Joshu, Martha L. Slattery, Amanda I. Phipps, Bethany Van Guelpen, Marc J. Gunter, Hermann Brenner, John D. Potter, Vicente Martín, Andrew T. Chan, Temitope O. Keku, Ludmila Vodickova, D. Timothy Bishop, Graham G. Giles, Susan M. Gapstur, Daniel D. Buchanan, Hansong Wang, Catherine M. Tangen, Alicja Wolk, Michael O. Woods, Sun-Seog Kweon, Jane C. Figueiredo, Stéphane Bézieau, Caroline J. Bull, Wen-Yi Huang, Michael Hoffmeister, Cornelia M. Ulrich, Robert E. Schoen, Eleanor Sanderson, Demetrius Albanes, Victor Moreno, Jenny Chang-Claude, Tilman Kühn, Clemens Schafmayer, J. Ramón Quirós, Shuji Ogino, Polly A. Newcomb, Ulrike Peters, Elio Riboli, Jochen Hampe, Heather Hampel, Kala Visvanathan, Sergi Castellví-Bel, Anna H. Wu, Neil Murphy, Mark A. Jenkins, Kostas Tsilidis, Andrea Gsur, Andrea N. Burnett-Hartman, George Davey Smith, Albert de la Chapelle, Emma E. Vincent, Amanda J. Cross
Publikováno v:
BMC Medicine 18 (2020) 1
Dipòsit Digital de la UB
Universidad de Barcelona
BMC Medicine
Bull, C J, Bell, J A, Sanderson, E, Davey Smith, G, Timpson, N J, Gunter, M J & al., E 2020, ' Adiposity, metabolites, and colorectal cancer risk : Mendelian randomization study ', BMC Medicine, vol. 18, 396 (2020) . https://doi.org/10.1186/s12916-020-01855-9
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Medicine, 18(1)
Dipòsit Digital de la UB
Universidad de Barcelona
BMC Medicine
Bull, C J, Bell, J A, Sanderson, E, Davey Smith, G, Timpson, N J, Gunter, M J & al., E 2020, ' Adiposity, metabolites, and colorectal cancer risk : Mendelian randomization study ', BMC Medicine, vol. 18, 396 (2020) . https://doi.org/10.1186/s12916-020-01855-9
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
BMC Medicine, 18(1)
Background Higher adiposity increases the risk of colorectal cancer (CRC), but whether this relationship varies by anatomical sub-site or by sex is unclear. Further, the metabolic alterations mediating the effects of adiposity on CRC are not fully un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57ac1dc5327f394332b4f3e350bf0ac0
https://research.wur.nl/en/publications/adiposity-metabolites-and-colorectal-cancer-risk-mendelian-random
https://research.wur.nl/en/publications/adiposity-metabolites-and-colorectal-cancer-risk-mendelian-random
Autor:
Renata Kozevnikovova, Miloslav Ambrus, Michal Kroupa, Kari Hemminki, Ludmila Vodickova, Sivaramakrishna Rachakonda, Michaela Schneiderova, Rajesh Kumar, Ludovit Musak, Zdenka Polivkova, Pavel Vodicka, Sona Vodenkova
Publikováno v:
Oncology reports. 44(5)
Accumulation of non‑specific structural chromosomal aberrations (CAs) and telomere shortening contribute to genome instability, which constitutes as one of the hallmarks of cancer. CAs arise due to direct DNA damage or telomere shortening. CAs in p