Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Martin Egli"'
Publikováno v:
Nucleic Acids Research
Even in high-quality X-ray crystal structures of oligonucleotides determined at a resolution of 1 Å or higher, the orientations of first-shell water molecules remain unclear. We used cryo neutron crystallography to gain insight into the H-bonding pa
Publikováno v:
Acta Crystallographica Section F Structural Biology Communications. 74:603-609
Crystals of left-handed Z-DNA [d(CGCGCG)]2diffract X-rays to beyond 1 Å resolution, feature a small unit cell (∼18 × 31 × 44 Å) and are well hydrated, with around 90 water molecules surrounding the duplex in the asymmetric unit. The duplex show
Publikováno v:
Crystals, Vol 9, Iss 10, p 532 (2019)
Crystals
Volume 9
Issue 10
Crystals
Volume 9
Issue 10
The (4&prime
&rarr
6&prime
)-linked DNA homolog 2&prime
3&prime
dideoxy-&beta
D-glucopyranosyl nucleic acid (dideoxy-glucose nucleic acid or homo-DNA) exhibits stable self-pairing of the Watson&ndash
Crick and rever
&rarr
6&prime
)-linked DNA homolog 2&prime
3&prime
dideoxy-&beta
D-glucopyranosyl nucleic acid (dideoxy-glucose nucleic acid or homo-DNA) exhibits stable self-pairing of the Watson&ndash
Crick and rever
Leveraging structural biology tools, we report the results of experiments seeking to determine if the different mechanical properties of DNA polymers with base analog substitutions can be attributed, at least in part, to induced changes from classica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7f1e76245d8428542dd71ff54eba870
https://europepmc.org/articles/PMC6251417/
https://europepmc.org/articles/PMC6251417/
Autor:
Ewa A. Kowal, Michael P. Stone, Manjori Ganguly, Barry Gold, Luis A. Marky, Martin Egli, Pradeep S. Pallan
Publikováno v:
The Journal of Physical Chemistry. B
As part of an ongoing effort to explore the effect of major groove electrostatics on the thermodynamic stability and structure of DNA, a 7-deaza-2'-deoxyadenosine:dT (7-deaza-dA:dT) base pair in the Dickerson-Drew dodecamer (DDD) was studied. The rem
Publikováno v:
Nucleic Acids Research
The crystal structure of the duplex formed by oligo(2',3'-dideoxy-beta-d-glucopyranosyl)nucleotides (homo-DNA) revealed strongly inclined backbone and base-pair axes [Egli,M., Pallan,P.S., Pattanayek,R., Wilds,C.J., Lubini,P., Minasov,G., Dobler,M.,
Publikováno v:
Crystals; Volume 6; Issue 10; Pages: 125
Crystals, Vol 6, Iss 10, p 125 (2016)
Crystals, Vol 6, Iss 10, p 125 (2016)
Phasing of nucleic acid crystal diffraction data using the anomalous signal of phosphorus, P-SAD, at Cukα wavelength has been previously demonstrated using Z-DNA. Since the original work on P-SAD with Z-DNA there has been, with a notable exception,