Zobrazeno 1 - 3
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pro vyhledávání: '"Rao V. Mantri"'
Autor:
Rao V. Mantri, Alexej Jerschow, Dolapo Olusanmi, Daniel McNamara, Andrew J. Ilott, David Good, Murphy Denette K, Anuji Abraham
Publikováno v:
Journal of Pharmaceutical Sciences. 105:1907-1913
Understanding the behavior of tablet disintegrants is valuable in the development of pharmaceutical solid dosage formulations. In this study, high-resolution magnetic resonance imaging has been used to understand the hydration behavior of a series of
Publikováno v:
AAPS PharmSciTech. 18:42-48
This study aimed in understanding the degradation behaviors of an IgG 1 subtype therapeutic monoclonal antibody A (mAb-A) associated with pH and buffer species. The information obtained in this study can augment conventional, stability-based screenin
Publikováno v:
Journal of pharmaceutical sciences. 105(3)
To support dose reduction, low dose of a monoclonal antibody (mAb) was required to be administered via IV infusion at a concentration of 0.1 mg/mL. To achieve the target protein concentration, the infusion solution was prepared by diluting the drug p