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Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
Inhaled antibiotics are commonly used to treat persistent airway infection with Pseudomonas aeruginosa that contributes to lung damage in people with cystic fibrosis. Current guidelines recommend inhaled tobramycin for individuals with cystic fibrosi
Autor:
Martijn Gerritsen, Marek Rajzer, Giovambattista Desideri, Cristina Giannattasio, Anne-Kathrin Tausche, Claudio Borghi, Michael T. Nurmohamed
Publikováno v:
European Heart Journal-Cardiovascular Pharmacotherapy, 8(3), 236-242. Oxford University Press
Desideri, G, Rajzer, M, Gerritsen, M, Nurmohamed, M T, Giannattasio, C, Tausche, A-K & Borghi, C 2022, ' Effects of intensive urate lowering therapy with febuxostat in comparison with allopurinol on pulse wave velocity in patients with gout and increased cardiovascular risk : the FORWARD study ', European heart journal. Cardiovascular pharmacotherapy, vol. 8, no. 3, pp. 236-242 . https://doi.org/10.1093/ehjcvp/pvaa144
European heart journal. Cardiovascular pharmacotherapy, 8(3), 236-242. Oxford University Press
Desideri, G, Rajzer, M, Gerritsen, M, Nurmohamed, M T, Giannattasio, C, Tausche, A-K & Borghi, C 2022, ' Effects of intensive urate lowering therapy with febuxostat in comparison with allopurinol on pulse wave velocity in patients with gout and increased cardiovascular risk : the FORWARD study ', European heart journal. Cardiovascular pharmacotherapy, vol. 8, no. 3, pp. 236-242 . https://doi.org/10.1093/ehjcvp/pvaa144
European heart journal. Cardiovascular pharmacotherapy, 8(3), 236-242. Oxford University Press
Aims Hyperuricaemia and gout are strongly related with traditional cardiovascular risk factors and vascular damage. This study aimed to assess whether febuxostat and allopurinol could differently influence carotid-femoral pulse wave velocity (cfPWV)
Autor:
Laxminarayan Karanth, Bradford A. Woodworth, Veena K.L. Karanth, Bryan K. Ward, Tulasi Kota Karanth
Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
BACKGROUND: Chronic rhinosinusitis frequently occurs in people with cystic fibrosis. Several medical interventions are available for treating chronic rhinosinusitis in people with cystic fibrosis; for example, different concentrations of nasal saline
Autor:
Daniel Moj, Nicola Ammer, Babette Aicher, Jan-Georg Wojtyniak, Thorsten Lehr, Michael Teifel, Herbert Sindermann, Hannah Britz, Nina Hanke
Zoptarelin doxorubicin is a fusion molecule of the chemotherapeutic doxorubicin and a luteinizing hormone-releasing hormone receptor (LHRHR) agonist, designed for drug targeting to LHRHR positive tumors. The aim of this study was to establish a physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c5e9a18956370d7aca5ee1061fd910
Autor:
Cintia V Cruz, Paula Schaiquevich, Carlos A Pérez Montilla, Gabriela Reyes Valenzuela, Paulo Cáceres Guido, Facundo García Bournissen, Roberto Caraballo
Background: Cannabidiol (CBD) is a nonpsychoactive natural product that has been increasingly used as a promising new drug for the management of neurological conditions such as refractory epilepsy. Development of rapid and sensitive methods to quanti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6450fcd9997e851e4532077b12d00108
https://doi.org/10.1097/ftd.0000000000000846
https://doi.org/10.1097/ftd.0000000000000846
Autor:
Gianmarco Bellucci, Ferdinando Nicoletti, Marika Alborghetti, Diego Centonze, Chiara Calderoni, Marco Salvetti, Antonietta Gentile, Ruggero Capra
Publikováno v:
Current Neuropharmacology. 20:107-125
Since COVID-19 has emerged as a word public health problem, attention has been focused on how immune suppressive drugs used for the treatment of autoimmune disorders influence the risk for SARS-CoV-2 infection and the development of the acute respira
Autor:
Marco Schiavone, Alessio Gasperetti, Claudio Tondo, Massimo Galli, Gianfranco Mitacchione, Giovanni Battista Forleo, Maurizio Viecca, Piercarlo Sarzi-Puttini
Publikováno v:
Current Reviews in Clinical and Experimental Pharmacology. 16:306-317
While facing potentially high morbidity from COVID-19 without known effective therapies, the off-label use of several non-specific drugs has been advocated, including re-purposed anti- viral (e.g., remdesivir or the lopinavir/ritonavir combination),
Autor:
Christiane Mühle, Valery Grinevich, Johannes Kornhuber, Patrick Bach, Christian Weinland, Falk Kiefer, Bernd Lenz, Iulia Zoicas
Publikováno v:
European Neuropsychopharmacology. 51:55-67
Alcohol use disorder (AUD) is a severe illness, for which we lack sufficient mechanistic understanding. Preliminary evidence associates AUD with the oxytocin (OXT) system. Here we investigated alterations in endogenous OXT blood concentrations in pat
Autor:
Ramona Nudischer, Adrian Roth, Vanessa Baier, Lars M. Blank, José V. Castell, Jens M. Kelm, Annika R. P. Schneider, Florian Caiment, Hans Gmuender, Christoph Thiel, Lars Kuepfer, Wolfgang Moritz, Yannick Schrooders, Henrik Cordes, Jos C. S. Kleinjans, Christian Trautwein, Timo Wittenberger, Olivia Clayton, Ulf P. Neumann
Publikováno v:
Clinical pharmacology & therapeutics : CPT 110(5), 1293-1301 (2021). doi:10.1002/cpt.2406
Clinical Pharmacology & Therapeutics, 110(5), 1293-1301. Wiley
CLINICAL PHARMACOLOGY & THERAPEUTICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
Clinical Pharmacology & Therapeutics, 110(5), 1293-1301. Wiley
CLINICAL PHARMACOLOGY & THERAPEUTICS
r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe
instname
We present a generic workflow combining physiology-based computational modeling and in vitro data to assess the clinical cholestatic risk of different drugs systematically. Changes in expression levels of genes involved in the enterohepatic circulati
Autor:
Fadime Ulviye Yigit, Muberra Akdogan, Ali Ihsan Tasci, Serdar Karadağ, Ismail Umut Onur, Mustafa Dogan, Mehmet Cem Sabaner
Publikováno v:
Journal of Ocular Pharmacology and Therapeutics. 37:421-429
Purpose: To evaluate the effects of a single dose of oral 5-mg tadalafil on macular microcirculation as measured using optical coherence tomography (OCT) and angiography (OCTA) in healthy volunteer...