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Autor:
Ron Wald, Mary K. Tan, Kim A. Connelly, Anatoly Langer, Hwee Teoh, Lawrence A. Leiter, Hirmand Nouraei, Shaun G. Goodman, Alice Y.Y. Cheng, Andrew T. Yan
Publikováno v:
Canadian Journal of Diabetes. 45:743-749
Optimal control of cardiovascular risk factors in adults with type 2 diabetes (T2D) and chronic kidney disease (CKD) is challenging. Limited data are available from the primary care setting on achievement of guideline-recommended targets in this popu
Autor:
Burcin Meryem Atak Tel, Gulali Aktas, Tuba Taslamacioglu Duman, Buse Balci, Asli Erturk, Ozge Kurtkulagi, Satilmis Bilgin, Gizem Kahveci
Publikováno v:
Romanian Journal of Internal Medicine, Vol 59, Iss 4, Pp 403-408 (2021)
Background. Hashimoto’s thyroiditis (HT) is an auto-immune condition characterized with lymphocytic and fibroblastic infiltration of the thyroid gland. The rate of uric acid and HDL cholesterol – so called as uric acid to HDL ratio (UHR) has been
Publikováno v:
Journal of Proteome Research. 20:5036-5053
A suboptimal blood vitamin C (ascorbate) level increases the risk of several chronic diseases. However, the detection of hypovitaminosis C is not a simple task, as ascorbate is unstable in blood samples. In this study, we examined the serum proteome
Autor:
Nicola Longo, Daniela Terracciano, Francesco Del Giudice, Giuseppe Lucarelli, Angelo Porreca, Pasquale Ditonno, Angelo Luciano, Carlo Buonerba, Alessandro Antonelli, Vincenzo Caputo, Rocco Damiano, Pasquale Dolce, Michele Marchioni, Fabio Crocerossa, Paolo Gontero, Stefania Zamboni, Matteo Manfredi, Antonio Verde, Michele Battaglia, Dario Ribera, Francesco Porpiglia, Gennaro Musi, Francesco Cantiello, Andrea Minervini, Felice Crocetto, Ottavio De Cobelli, Giuseppe Celentano, Vincenzo Cosimato, Mihai Dorin Vartolomei, Nicolae Crisan, Andrea Mari, Giorgio Ivan Russo, Abdal Rahman Abu Farhan, Francesco Greco, Francesco Soria, Francesco Chiancone, Luca Scafuri, Paola Del Prete, Rodolfo Hurle, Pietro De Placido, Giuseppe Di Lorenzo, Sergio Facchini, Matteo Ferro, Riccardo Autorino, Sisto Perdonà, Gian Maria Busetto
Publikováno v:
Future Oncology. 17:3987-3994
The objective of the current research was to explore the potential prognostic value of readily available clinical and pathologic variables in bladder cancer. The novel association found between cholesterol levels and prognosis may provide the rationa
Autor:
Vinayak Gupta, Poovitha Sundar, Nitish R. Mahapatra, Bhargavi Natarajan, S Santosh Reddy, Vikas Arige, Abrar A. Khan, Manoj Kumar Barthwal
Publikováno v:
Journal of Molecular and Cellular Cardiology. 158:140-152
3-Hydroxy-3-methyl glutaryl-coenzyme A reductase (Hmgcr) encodes the rate-limiting enzyme in the cholesterol biosynthesis pathway. The regulation of Hmgcr in rat models of genetic hypertension (viz. Spontaneously Hypertensive Rat [SHR] and its normot
Autor:
Valentina Nardi, Amir Lerman, Kyra L. Jordan, Megha Prasad, Xiang Y. Zhu, Federico Franchi, Hui Tang, Morsaleh Ganji, Lilach O. Lerman, Melissa D. Young, Melanie C. Bois
Publikováno v:
Stroke. 52:2792-2801
Background and Purpose: XO (xanthine oxidase) is a key enzyme of uric acid metabolism and is thought to contribute to oxidative pathways that promote atherosclerotic plaque progression, yet its role in plaque destabilization is not well elucidated. W
Autor:
Kelsey A Schmidt, Jessica N. Kuzma, Kristina M. Utzschneider, Imashi Fernando, Sarah Holte, Gail Cromer, Derek K. Hagman, Maggie S Burhans, Jana Kraft, Mario Kratz, Merideth Murray
Publikováno v:
Am J Clin Nutr
Background Dietary guidelines traditionally recommend low-fat dairy because dairy's high saturated fat content is thought to promote cardiovascular disease (CVD). However, emerging evidence indicates that dairy fat may not negatively impact CVD risk
Autor:
Janice Campbell, Maike Rahn, Adish Ezatagha, Susan E Spruill, YiFang Chu, Elhadji M. Dioum, Alexandra L Jenkins, Thomas M.S. Wolever
Publikováno v:
The Journal of Nutrition. 151:2655-2666
Background High-molecular-weight (MW) oat β-glucan (OBG), consumed at 3-4 g/d, in solid foods reduces LDL cholesterol by a median of ∼6.5%. Objectives We evaluated the effect of a beverage providing 3 g/d high-MW OBG on reduction of LDL cholestero
Autor:
Lee Smith, Edineia de Brito, Aline Josiane Waclawovsky, Davy Vancampfort, Antônio Marcos Vargas da Silva, Felipe Barreto Schuch
Publikováno v:
Journal of Psychiatric Research. 141:152-159
The study aimed to identify whether people diagnosed with depression have endothelial dysfunction, assessed by the technique of flow-mediated dilation (FMD), when compared to controls without depression. In addition, to verify whether people with dep
Autor:
Merve Acikel Elmas, Feriha Ercan, M. Kutay Köroğlu, Nesrin Kartal Ozer, Tugce Demirel-Yalciner, Erdi Sozen
Publikováno v:
IUBMB Life. 74:85-92
The seminiferous tubules where spermatogenesis occurs are enveloped and protected by the Sertoli cells to support germ cells undergoing meiosis to produce haploid gametes. Clearly, induction of apoptosis in seminiferous tubules leads to abnormalities