Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Li, Hao"'
Publikováno v:
OncoTargets and Therapy. 13:10489-10498
Background Colorectal cancer is one of the three most common cancers worldwide. Altered TGF-β signaling pathway in colorectal cancer is associated with metastasis and poor prognosis. It is also involved in epithelial-to-mesenchymal transition (EMT),
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 20, Iss 1, Pp 1-20 (2020)
BMC Complementary Medicine and Therapies
BMC Complementary Medicine and Therapies
Background Sedum sarmentosum is traditionally used to treat various inflammatory diseases in China. It has protective effects against acute liver injury, but the exact mechanism of such effects remains unclear. This study investigated the protective
Autor:
Yixuan Jing, Bei Tao, Hong-yan Zhao, Li-hao Sun, Xiaojing Wang, Jingjia Yu, Jian-min Liu, Yanman Zhou, Xiaofeng Wang
Publikováno v:
Journal of Diabetes. 12:426-437
BACKGROUND Type 2 diabetes mellitus (T2DM) is associated with a higher fracture risk. Sex hormones are important for maintaining skeletal health. It is not clear which sex hormone(s) contribute(s) to bone mineral density (BMD) and fracture risk in ma
Publikováno v:
Digestive Diseases and Sciences. 65:470-479
Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by the highly selective autoimmune injury of small intrahepatic bile ducts. Studies reported that the cholangiocytes from PBC patients expressed significantly higher level
Autor:
Gwendalyn J. Randolph, Li-Hao Huang, Brad W. Warner, W. Sean Davidson, Mary Wohltmann, Robert W. Sprung, Yong-Hyun Han, Emily J. Onufer, Mary G. Sorci-Thomas, Rafael S. Czepielewski
Publikováno v:
Science
Intestinal HDL is hepatoprotective High-density lipoprotein (HDL) is important for cholesterol metabolism and may have anti-inflammatory and antimicrobial properties. Although HDL is mainly produced by the liver, the intestine is also a source. Han e
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1825, p 1825 (2021)
Volume 22
Issue 4
International Journal of Molecular Sciences, Vol 22, Iss 1825, p 1825 (2021)
Bam32 (B cell adaptor molecule of 32 kDa) functions in the immune responses of various leukocytes. However, the role of neutrophil Bam32 in inflammation is entirely unknown. Here, we determined the role of Bam32 in chemokine CXCL2-induced neutrophil
Publikováno v:
Journal of Leukocyte Biology. 106:1117-1127
PI3K has been indicated in regulating microvascular permeability changes during inflammation. However, its role in neutrophil-driven microvascular leakage in acute inflammation remains unclear. Using intravital microscopy in mice, we examined the rol
Autor:
Li Hao, Wenna Zhang, Baoan Wang, Qiulei Zhang, Yi Zhang, Shengnan Wang, Feng Jiang, Shengyuan Wang, Chaoran Xu, Yunfei Yu, Tianzhong Li
Publikováno v:
Plant Science. 280:424-432
The grafting of horticultural crops enables breeders to induce phenotypic changes in rootstocks and scions. A number of signaling molecules, including RNAs and proteins, were recently shown to underlie these changes; however, little is known about th
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-16 (2019)
BMC Pulmonary Medicine
BMC Pulmonary Medicine
Background Reactive oxygen species (ROS) levels largely determine pulmonary fibrosis. Antioxidants have been found to ameliorate lung fibrosis after long-term paraquat (PQ) exposure. The effects of antioxidants, however, on the signalling pathways in
Autor:
Yu-ying Yang, Wei Qing Wang, Chang Shan, Yan yun Gu, Qian qian Zhuang, Xiao ke Kong, Jian-min Liu, Hong Yan Zhao, Yan ling Gong, Si yue Zhuang, Shu-min Wang, Guang Ning, Bei Tao, Yan fang Hou, Sheng-Tian Li, Xing zhi Guo, Arijit Ghosh, Ke cheng Zhu, Li hao Sun
Publikováno v:
Microbiome
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Microbiome, Vol 9, Iss 1, Pp 1-17 (2021)
Background Parkinson’s disease (PD) is a neurodegenerative disorder with no absolute cure. The evidence of the involvement of gut microbiota in PD pathogenesis suggests the need to identify certain molecule(s) derived from the gut microbiota, which